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Dataset results
84 results for “HCMV”
N6-methyladenosine modification of HCMV IE1 transcript promotes the repressive state of viral genome to achieve latent infection
GEO Series GSE279262. Homo sapiens; Human betaherpesvirus 5. 12 samples. Type: Other.
Role of the HCMV immediate early proteins in controlling the HCMV transcriptome
GEO Series GSE171521. Homo sapiens; Human betaherpesvirus 5. 4 samples. Type: Expression profiling by high throughput sequencing.
Cytomegalovirus promotes maintenance and growth of glioblastoma stem cells [HCMV gene expression]
GEO Series GSE56750. Homo sapiens; Human betaherpesvirus 5. 2 samples. Type: Expression profiling by array.
HCMV infected Human Fibroblasts UL84 IE2 ChIPSeq
GEO Series GSE169634. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
HCMV transcriptome during early lytic infection
GEO Series GSE171520. Homo sapiens; Human betaherpesvirus 5. 2 samples. Type: Expression profiling by high throughput sequencing.
Pol2 and H3K27Ac and H3K27me3 occupancy of the viral genome in HCMV infected Kasumi-3 cells at early times post infection
GEO Series GSE164844. Human betaherpesvirus 5. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Differential Genome Expression in AhR-KD and Control HCMV-Infected Fibroblasts
GEO Series GSE159375. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Time course analysis of response to HCMV infection
GEO Series GSE675. Homo sapiens. 12 samples. Type: Expression profiling by array.
Expression Data From HCMV-Infected Human Monocytes: Role of EGFR
GEO Series GSE17948. Homo sapiens. 16 samples. Type: Expression profiling by array.
RNA-seq profiling of gene expression in mock-infected and human cytomegalovirus (HCMV)–infected human embryonic lung fibroblasts (HELF) at 72 hours post infection (two biological replicates per condit
GEO Series GSE307100. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcription start site profiling of HCMV infected cells using dRNA-seq and STRIPE-seq with temporal kinetics using SLAM-seq
GEO Series GSE191299. Homo sapiens. 36 samples. Type: Other.
DNA virus infections shape transposable element activity in vitro and in vivo (HCMV,KSHV,DUX4)
GEO Series GSE280380. Homo sapiens. 54 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
HCMV-UV and SeV-UV infection of IFNAR KO and wildtype human fibroblasts
GEO Series GSE149705. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
CAGE-seq Profiling of Transcription Start Site Usage in mock-infected and human cytomegalovirus (HCMV) infected human embryonic lung fibroblasts (HELF) cells (human)
GEO Series GSE307101. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT"
<p>This record contains data set related to the article "Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT"</p> <p>Haploidentical hematopoietic stem cell transplantation (h-HSCT) represents an efficient curative approach for patients affected by hematologic malignancies in which the reduced intensity conditioning induces a state of immunologic tolerance between donor and recipient. However, opportunistic viral infections greatly affect h-HSCT clinical outcomes. NK cells are the first lymphocytes that recover after transplant and provide a prompt defense against human cytomegalovirus (HCMV) infection/reactivation. By undertaking a longitudinal single-cell computational profiling of multiparametric flow cytometry, we show that HCMV accelerates NK cell immune reconstitution together with the expansion of CD158b1b2jpos/NKG2Aneg/NKG2Cpos/NKp30lo NK cells. The frequency of this subset correlates with HCMV viremia, further increases in recipients experiencing multiple episodes of viral reactivations, and persists for months after the infection. The transcriptional profile of FACS-sorted CD158b1b2jpos NK cells confirmed the ability of HCMV to deregulate NKG2C, NKG2A, and NKp30 gene expression, thus inducing the expansion of NK cells with adaptive traits. These NK cells are characterized by the downmodulation of several gene pathways associated with cell migration, the cell cycle, and effector-functions, as well as by a state of metabolic/cellular exhaustion. This profile reflects the functional impairments of adaptive NK cells to produce IFN-γ, a phenomenon also due to the viral-induced expression of lymphocyte-activation gene 3 (LAG-3) and programmed cell death protein 1 (PD-1) checkpoint inhibitors.</p>
RNA-seq transcriptome analysis of HCMV (AD169) and mock infected MRC5 fibroblasts
GEO Series GSE210989. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Comparative transcriptome analysis implicates IL1R8-associated upregulation of myeloid leukocyte pathways in latent HCMV infection
GEO Series GSE173290. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Human gene expression altered by Human cytomegalovirus (HCMV) Entry
GEO Series GSE27974. Homo sapiens. 2 samples. Type: Expression profiling by array.
RNA-sequencing of HCMV-infected ARPE-19 and MCF10A cells
GEO Series GSE290998. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
HCMV infection of human neural precursor cells
GEO Series GSE31142. unidentified; Homo sapiens; Human betaherpesvirus 5. 5 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.