Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
767
datasets available to search
ShareScore release 0.9.0
Dataset results
767 results for “High throughput sequencing”
Evaluation of the Diagnostic Contribution of High-throughput Exome Sequencing for Patients With Convulsive Encephalopathy of Unknown Etiology: Pilot Study to Improve Genetic Counselling
ClinicalTrials.gov study NCT03652246. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A confidence interval analysis of sampling effort, sequencing depth, and taxonomic resolution of fungal community ecology in the era of high-throughput sequencing.
Open the record for dataset details and reuse information.
Data from: High-throughput sequencing of nematode communities from total soil DNA extractions
Open the record for dataset details and reuse information.
Data from: High-throughput SNP genotyping of historical and modern samples of five bird species via sequence capture of ultraconserved elements
Open the record for dataset details and reuse information.
Data from: Changes in soil microbial communities in post mine ecological restoration: implications for monitoring using high throughput DNA sequencing
Open the record for dataset details and reuse information.
Data from: Targeted gene enrichment and high-throughput sequencing for environmental biomonitoring: a case study using freshwater macroinvertebrates
Open the record for dataset details and reuse information.
Data from: Digital fragment analysis of short tandem repeats by high-throughput amplicon sequencing
Open the record for dataset details and reuse information.
Data from: Comparison and validation of Oomycetes metabarcoding primers for Phytophthora high throughput sequencing
Open the record for dataset details and reuse information.
Data from: High-throughput sequencing of ancient plant and mammal DNA preserved in herbivore middens
Open the record for dataset details and reuse information.
Data from: Development, validation and high-throughput analysis of sequence markers in nonmodel species
Open the record for dataset details and reuse information.
Data from: High-throughput sequencing of transposable element insertions suggests adaptive evolution of the invasive Asian Tiger Mosquito towards temperate environments
Open the record for dataset details and reuse information.
Data from: Seasonal diversity and dynamics of haptophytes in the Skagerrak, Norway, explored by high-throughput sequencing
Open the record for dataset details and reuse information.
Data from: Diet assessment of two land planarian species using high-throughput sequencing data
Open the record for dataset details and reuse information.
A high-throughput skim-sequencing approach for genotyping, dosage estimation and identifying translocations
Open the record for dataset details and reuse information.
Data from: Who’s for dinner? High-throughput sequencing reveals bat diet differentiation in a biodiversity hotspot where prey taxonomy is largely undescribed
Open the record for dataset details and reuse information.
Data from: Use of genotyping-by-sequencing data to develop a high-throughput and multi-functional SNP panel for conservation applications in Pacific lamprey
Open the record for dataset details and reuse information.
Data from: High-throughput sequencing of Bacillus anthracis in France: investigating genome diversity and population structure using whole-genome SNP discovery
Open the record for dataset details and reuse information.
Data from: A phylogeny of birds based on over 1,500 loci collected by target enrichment and high-throughput sequencing
Open the record for dataset details and reuse information.
Data from: High-throughput amplicon sequencing of rRNA genes requires a copy number correction to accurately reflect the effects of management practices on soil nematode community structure
Open the record for dataset details and reuse information.
Data from: More affordable and effective noninvasive SNP genotyping using high-throughput amplicon sequencing
<p>Non-invasive genotyping methods have become key elements of wildlife research over the last two decades, but their widespread adoption is limited by high costs, low success rates, and high error rates. <span>The information lost when genotyping success is low may lead to decreased precision in animal population densities, which could misguide conservation and management actions.</span> <span>Single nucleotide polymorphisms (SNPs) provide a promising alternative to traditionally used microsatellites as SNPs allow amplification of shorter DNA fragments, are less prone to genotyping errors, and produce results that are easily shared among laboratories.</span> Here, we outline a detailed protocol for cost-effective and accurate noninvasive SNP genotyping using multiplexed amplicon sequencing optimized for degraded DNA. <span>We validated this method for individual identification by genotyping 216 scats, 18 hairs and 15 tissues from coyotes (<i>Canis latrans</i>) using 26 SNPs. </span><a name="_Hlk33181599">Our genotyping success rate for scat samples was 93%, and 100% for hair and tissue, representing a substantial increase compared to previous microsatellite-based studies while remaining at a low cost of under $5 per PCR replicate (excluding labor). </a>The accuracy of the genotypes was further corroborated in that genotypes from scats matching known, GPS-collared coyotes were always located within the territory of the known individual. We also show that different levels of multiplexing produced similar results, but that PCR product cleanup strategies can have substantial effects on genotyping success. By making noninvasive genotyping more affordable, accurate, and efficient, this research may allow for a substantial increase in the use of noninvasive methods to monitor and conserve free-ranging wildlife populations.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.