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3,223 results for “Human Study”
Deadly dormmate: a case study on Bungarus candidus living among a student dormitory with implications for human safety
<p>Movement and observation data gained through radio-telemetry of a single Malayan krait (<em>Bungarus candidus</em>) among a suburban landscape (a university dormitory complex) in NE Thailand. Included: movement spatial data .csv file and photographic evidence of foraging observations, a predation events, and conflicts with humans, camera trap footage, and snakebite incident data .csv file.</p> <p> </p> <p>B.candidus_observation_data.csv file column headings:</p> <p>folderID: The Zenodo folder ID containing the photographic evidence of events.</p> <p>obvdate: Date of observation (mm/dd/yyyy)</p> <p>obvtime: Time of observation (24hr)</p> <p>easting_utm: UTM easting (UTM Zone 48N; Datum WGS84)</p> <p>northing_utm: UTM northing (UTM Zone 48N; Datum WGS84)</p> <p>gps_accuracy: Accuracy of GPS location (m)</p> <p>notes: Comments and details on events/observations</p> <p> </p> <p>BUCA28_movement_data.csv file column headings:</p> <p>Datetime: Date and time when the snake was located (mm/dd/yyyy hh:mm)</p> <p>Easting: UTM easting (UTM Zone 48N; Datum WGS84)</p> <p>Northing: UTM northing (UTM Zone 48N; Datum WGS84)</p> <p>Behavior: Either the animal’s behavior observed during the location check (sheltering, foraging, or feeding) or type of other significant locations (capture or release sites)</p> <p>Habitat_Type: Land-use type where the snake was located</p> <p> </p> <p>Snakebite_incident_data_SUT_Dormitories.csv file column headings:</p> <p>Date: Date the snakebite occurred was located (mm/dd/yyyy)</p> <p>Time: Time (ICT) the snakebite occurred (hh:mm)</p> <p>Location: Brief location description where the incident occurred at Suranaree University of Technology</p> <p>Mesohabitat Description: Brief description of the scene where the bite occurred</p> <p> Snake species confirmed?: if responsible species known (Yes) or unknown (No)</p> <p>Snake Species: Identified responsible snake species (if known)</p> <p>If not confirmed, suspected species responsible: Species most likely to be responsible based on known snake species at SUT, the time the bite occurred, and bite symptoms.</p> <p>Bite Location: Where on the body the victim was bitten</p> <p>Envenomation Symptoms: Brief description of bite symptoms (note: none were severe/dangerous cases)</p> <p>Fang Puncture Marks?: Brief description of whether fang puncture marks were visible, and if so, how many punctures</p> <p>Notes and Photos: Brief further notes on how the bite occurred, and in the case of the bite by C. maculiceps, the corresponding Zenodo folder ID containing the photographic evidence (of the snake and dormitory bite location [during daylight]).</p> <p> </p> <p> </p>
AnnData files for "Human dermal fibroblast subpopulations are conserved across single-cell RNA sequencing studies"
<p>AnnData files for "Human dermal fibroblast subpopulations are conserved across single-cell RNA sequencing studies". </p> <p>Includes Joined dataset with all four datasets at once.</p>
Data sharing in Human ancient DNA studies
<p>The dataset contains information on data sharing regarding mitochondrial, Y chromosomal and autosomal polymorphisms in a total of 162 papers on ancient human DNA published between 1988 and 2013.</p>
Computational Studies of Human Class V Alcohol Dehydrogenase - The Odd Sibling
<p>A number of class I-VI ADH protein sequences were obtained from the UniProt, NCBI protein database, and Ensembl databases in October 2015. The sequences were aligned using the L-INS-i approach of MAFFT 7.266.</p> <p>The tree was generated using Phyml release 20151210. In the published figure, the tree was visualised as a radial phylogram in Dendroscope 3.</p>
Dataset supporting "Violating instructed human agency: an fMRI study on oculomotor tracking of biological and nonbiological motion stimuli."
<p>Here we provide fMRI data used for the following project (for details see data description file): Gertz, H., Hilger, M., *Hegele, M., & *Fiehler, K. (2016). Violating instructed human agency: an fMRI study on oculomotor tracking of biological and nonbiological motion stimuli. Neuroimage, doi: 10.1016/j.neuroimage.2016.05.043. (*shared last authorship)</p> <p> </p> <p>Previous studies have shown that beliefs about the human origin of a stimulus are capable of modulating the coupling of perception and action. Such beliefs can be based on top-down recognition of the identity of an actor or bottom-up observation of the behavior of the stimulus. Instructed human agency has been shown to lead to superior tracking performance of a moving dot as compared to instructed computer agency, especially when the dot followed a biological velocity profile and thus matched the predicted movement, whereas a violation of instructed human agency by a nonbiological dot motion impaired oculomotor tracking (Zwickel et al., 2012). This suggests that the instructed agency biases the selection of predictive models on the movement trajectory of the dot motion. The aim of the present fMRI study was to examine the neural correlates of top-down and bottom-up modulations of perception–action couplings by manipulating the instructed agency (human action vs. computer-generated action) and the observable behavior of the stimulus (biological vs. nonbiological velocity profile). To this end, participants performed an oculomotor tracking task in an MRI environment. Oculomotor tracking activated areas of the eye movement network. A right-hemisphere occipito-temporal cluster comprising the motion-sensitive area V5 showed a preference for the biological as compared to the nonbiological velocity profile.Importantly,a mismatch between instructed human agency and a nonbiological velocity profile primarily activated medial-frontal areas comprising the frontal pole, the paracingulate gyrus, and the anterior cingulate gyrus, as well as the cerebellum and the supplementary eye field as part of the eye movement network. This mismatch effect was specific to the instructed human agency and did not occur in conditions with a mismatch between instructed computer agency and a biological velocity profile. Our results support the hypothesis that humans activate a specific predictive model for biological movements based on their own motor expertise. A violation of this predictive model causes costs as the movement needs to be corrected in accordance with incoming (nonbiological) sensory information.</p>
Wildlife Diversity and the Impact of Human Disturbance on Activity Patterns: A Case Study of the Labagoumen Nature Reserve, Beijing, China
<p>This version updates the dataset to reflect revised analyses in the resubmitted manuscript to Ecology and Evolution.</p> <p><strong>Title:</strong><br><strong>Data and Code for "Wildlife Diversity and the Impact of Human Disturbance on Activity Patterns: A Case Study of the Labagoumen Nature Reserve, Beijing, China"</strong></p> <p><strong>Description:</strong><br>This dataset contains the raw data and R scripts used to generate specific figures in the manuscript <em>"Wildlife Diversity and the Impact of Human Disturbance on Activity Patterns: A Case Study of the Labagoumen Nature Reserve, Beijing, China,"</em> submitted to <em>Ecology and Evolution</em>. The data were collected from infrared camera traps deployed in the Labagoumen Nature Reserve, Beijing, China, between 2019 and 2022. The dataset includes species detection records, timestamps, and information relevant to assessing the effects of human disturbance on wildlife activity patterns.</p> <p>The accompanying R scripts facilitate data processing, statistical analyses, and figure generation, enabling reproduction of the key results. This dataset may be useful for researchers interested in spatiotemporal wildlife monitoring, human-wildlife interactions, and disturbance ecology.</p> <p><strong>Contents:</strong></p> <ul> <li>raw data (Excel format, <code>.xlsx</code>)</li> <li>R scripts for data analysis and figure generation of <strong>Figures 3-5</strong> (from the raw data file "raw data.xlsx") (Text format, .doc).</li> <li> <p><strong>Figure 1</strong>: Created using <span>ArcMap 10.8 software</span> and Photoshop software. <span>ArcMap 10.8 software </span>was used for processing spatial data and map creation, while Photoshop was used for post-processing and image enhancement.</p> </li> <li> <p><strong>Figure 2 and Appendix Figure. A1</strong>: Designed and modified using Photoshop software.</p> </li> </ul>
A data repository for the study of Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
<p><span>This repository contains data associated with the study:</span></p> <p><span><strong>"Alpha-synuclein Aggregates Trigger Anti-Viral Immune Pathways and RNA Editing in Human Astrocytes"</strong></span></p> <p><span>Published as a <strong>bioRxiv preprint</strong>: <a href="https://doi.org/10.1101/2024.02.26.582055"><span>DOI: 10.1101/2024.02.26.582055</span></a></span></p>
Additional data repository for the study of Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
<p>Zip file 1: astrocytes calcium data measured using Fura 2</p> <p>Zip file2: astrocytes ROS measured using DHE (Dihydroethidium)</p> <p>Zip file 3: astrocytes cell death measured using Sytox green</p>
Interactive study of human PTCD2 protein
<p>We investigated the intractome of human PTCD2 protein, a putative key player in non-canonical mitochondrial RNA processing, by Proximity-dependent Biotin Identification (BioID) followed by ESI-LC-MSMS. The dataset includes the results of the Mass spec analysis with detailed reports made by the proteomics core facility, University of Geneva. </p>
A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2
<p>Data produced and analyzed in the manuscript "A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2" by Pasquadibisceglie et al.</p> <p><br> If you include these data in your manuscript, please cite: Pasquadibisceglie A, Leccese A and Polticelli F (2022) A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2. <em>Front. Chem.</em> 10:1004815. doi: 10.3389/fchem.2022.1004815</p>
Real-time magnetic resonance imaging to study orthostatic intolerance mechanisms in human beings: Proof of concept
<p>This dataset was acquired at DLR, Cologne, Germany. The study complied with the Declaration of Helsinki, and was approved by the local ethics committee. All subjects gave written informed consent.</p> <p> </p> <p><strong>Data acquisition</strong><br> <em>MRI data</em></p> <p>All MR images were acquired on a Siemens 3T mMR Biograph using cardiac, spine and head coils. The scanning protocol consisted of the following sequences.</p> <ul> <li><strong>MPI70_SA20_FOV320_16X6MM_33MS</strong>: cardiac real-time MRI of the short axis (TR=2.56 ms; TE=1.62 ms; FA= 10°; 1.6x1.6 mm; 6 mm slice thickness; 20 slices; FoV320x320 mm; radial spokes 13)</li> <li><strong>MPI70_TP_PCMV100_FOV320_15X6MM_33MS</strong>: blood flow real-time MRI of the pulmonary trunk (TR=3.33 ms; TE=2.24 ms; FA= 10°; 1.5x1.5 mm; 6 mm slice thickness; FoV=320x320 mm; VENC=100 cm/s; radial spokes 5)</li> <li><strong>MPI70_PCMV100_FOV192_075X6MM_80MS:</strong> blood flow real-time MRI of the middle cerebral artery (TR=4.44 ms; TE=3.10 ms; FA= 12°; 0.75x0.75 mm; 6 mm slice thickness; FoV=192x192 mm; VENC=100 cm/s; radial spokes 9)</li> </ul> <p> </p> <p>Cinematic real-time MRI of the short axis view and blood flow measurements of the pulmonary trunk and in the left and right middle cerebral artery were acquired at baseline and during -30mmHg LBNP.</p> <p> </p> <p>Video files:</p> <p><a href="https://zenodo.org/record/7066642/files/Series_040_mpi70_SA20_FOV320_16x6mm_33ms_Slice_14.wmv?download=1">https://zenodo.org/record/7066642/files/Series_040_mpi70_SA20_FOV320_16x6mm_33ms_Slice_14.wmv?download=1</a></p> <p><a href="https://zenodo.org/record/7066642/files/Series_103_mpi70_SA20_FOV320_16x6mm_33ms_Slice_14.wmv?download=1">https://zenodo.org/record/7066642/files/Series_103_mpi70_SA20_FOV320_16x6mm_33ms_Slice_14.wmv?download=1</a></p> <p> </p> <p> </p>
Combining Dipole and Loop Coil Elements for 7 T Magnetic Resonance Studies of the Human Calf Muscle - Dataset
<p>Data necessray to reprodice and to verify the results of the publication "Combining Dipoles and Loops for High SNR and Parallel Imaging Performance in Human Calf Muscle Studies at 7 T".</p>
Data for "A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studies"
<p>Data for the manuscript: A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studies (see also https://doi.org/10.1101/2022.05.09.491139)</p>
Questionnaire data from a study on the perception of breathing in the human brain
<p>This dataset contains anonymized data (questionnaire scores) from a set of questionnaires acquried in a previous study. Version 1 of this dataset (<span><a href="https://doi.org/10.5281/zenodo.10992529" target="_blank" rel="noopener"><span>https://doi.org/10.5281/zenodo.10992529</span></a>)</span> contained summary data of a subset of all participants for a subset of the questionnaires. For details see the Readme.pdf. Version 2 contains all subscores of all questionnaires assessed in this study. See Readme_v2.pdf for details. </p>
A 3D multi-cellular tissue model of the human omentum to study mechanisms of ovarian cancer metastasis
<p>Here, the design of 3D multi-cellular tissue model of the human omentum is presented to study mechanisms of ovarian cancer metastasis.</p>
Dataset part two to the publication "CAL-1 as Cellular Model System to Study CCR7-Guided Human Dendritic Cell Migration"
<p>Additional dataset to dataset part one (doi: 10.5281/zenodo.4719596) to the publication "CAL-1 as Cellular Model System to Study CCR7-Guided Human Dendritic Cell Migration"</p>
Dataset for the study Sensitive period for the plasticity of alpha activity in humans
<p>Raw EEG data in european data format (EDF) format. Descriptive and clinical data of the subjects in textual tab delimited format. Columns report for each subject: group (blind/severely impaired, BSI or sighted, S), code, gender, age expressed in decimal years, age bin, degree of visual impairment, diagnosis, motor coordination impairment classification (MCI, 1 = not impaired, 2 = impaired), and hypotonia classification (1 = not impaired, 2 = impaired). NA correspond to undefined classification.</p> <p>Visual experience is crucial for the development of neural processing. For example, alpha activity development is a vision-dependent mechanism. Indeed, studies report no alpha activity is present in blind adults. Nevertheless, studies have not investigated the developmental trajectory of this activity in infants and children with blindness. Here, we hypothesize that the difference in neural activity of blind compared to sighted subjects is: absent at birth, progressive with age, specifically occipital and linked to a gradual motor impairment. Therefore, we consider spectral power of resting-state EEG and its association with motor impairment indices, in blind subjects and in sighted controls between 0 and 11 years of age. Blind subjects show posterior alpha activity during the first three years of life, although weaker and slower maturing compared to sighted subjects. The first great differentiation between blind and sighted subjects occurs between 3 and 6 years of age. Starting in this period, reduced alpha activity increases the probability of motor impairment in blind subjects, likely because of impaired perception/interaction. These results show that visual experience mediates the neural mechanisms generating alpha oscillations during the first years of life, suggesting that it is a sensitive period for the plasticity of this process.</p>
Integrating socio-ecological suitability with human-wildlife conflict risk: Case study for translocation of a large ungulate
<p>1. Translocations are essential for reestablishing wildlife populations. As they sometimes fail, it is critical to assess factors that influence their success pre-translocation.</p> <p>2. Socio-ecological suitability models (SESMs) integrate social acceptance and ecological suitability to enable identification of areas where wildlife populations will expand, which makes it likely that SESMs will also be useful for predicting translocation success.</p> <p>3. To inform site-selection for potential elk (Cervus canadensis) reintroduction to northeastern Minnesota, USA, we developed broad-scale maps of social acceptance from surveys of local residents and landowners, animal use equivalence (AUE) from forage measured in the field, and empirical conflict risk from geospatial data. Resulting SESMs integrated social acceptance favorability scores, AUE, and conflict risk, and weighted SESMs showed the relative influences of acceptance and conflict.</p> <p>4. Social acceptance was positive for local residents and landowners (mean ≥ 5.4; scale of 1 to 7). AUE (scaled to an elk home range) ranged between 1 and 9 elk/16 km2 during winter, and from 14 to 83 elk/16 km2 during summer. Human-elk conflict risk was low (mean ≤ 0.10; scaled 0 to 1), increasing from north to south. Geographical distributions differed for social acceptance, AUE, and conflict risk, and weighted SESMs revealed unsuitable areas that were otherwise obscured.</p> <p>5. <em>Synthesis and applications</em>. Integrating human-wildlife conflict risk into SESMs shows where social acceptance of translocated species is likely to erode, even where viewed favorably pre-translocation, to inform translocation planning by highlighting interactions between key factors. Such integrated models supplement existing reintroduction biology frameworks by supporting decision-making and knowledge development. In northeastern Minnesota, natural resource managers who are considering elk reintroductions are using SESMs reported here to identify where human-elk conflict is likely to result in an isolated elk population and where addressing concerns for area residents about conflict risk is essential.</p>
Knockout mice represent an important tool for the multisystemic study of human monogenic heart disease
<p>Supplementary data to support a manuscript entitled "Knockout mice represent an important tool for the multisystemic study of human monogenic heart disease"</p>
Isothermal titration calorimetric study on the binding of iron to human serum transferrin - experimental data
<p>Experimental data for a paper entitled <em>Glycoproteomics meets thermodynamics: a calorimetric study of the effect of sialylation and synergistic anion on the binding of iron to human serum transferrin</em> (<a href="https://doi.org/10.1016/j.jinorgbio.2023.112207">https://doi.org/10.1016/j.jinorgbio.2023.112207</a>).<br> <br> Separate files are provided with the following information:<br> <br> 1. ITC titrations of native (Tf+s) and desialylated (Tf-s) apo-transferrin with FeNTA in the presence of carbonate and oxalate.<br> <br> a) Raw data with corresponding fit results are available in .apj file format: <a href="https://zenodo.org/api/files/188f4399-e839-4710-8a28-996af05961aa/Borko et al. ITC - Malvern Microcal format.zip?versionId=e1a08c09-9401-42fa-a626-683a2fcc1be5">Borko et al. ITC - Malvern Microcal format.zip </a><br> <br> The files can be accessed using MicroCal PEAQ-ITC Analysis software, which can be downloaded here:<br> <br> <a href="https://www.malvernpanalytical.com/en/support/product-support/microcal-range/microcal-itc-range/microcal-peaq-itc#software">https://www.malvernpanalytical.com/en/support/product-support/microcal-range/microcal-itc-range/microcal-peaq-itc#software</a><br> <br> b) The raw data including control experiments are also available in ASCII (.csv) format: <a href="https://zenodo.org/api/files/188f4399-e839-4710-8a28-996af05961aa/Borko et al. ITC - ASCII format.zip?versionId=20ecf17b-54d9-4b33-8de9-a6f256211cc6">Borko et al. ITC - ASCII format.zip</a></p> <p>2. Overview of titration results, including error propagation and inputs for statistical analysis: <a href="https://zenodo.org/api/files/188f4399-e839-4710-8a28-996af05961aa/Borko%20et%20al.%20-%20Results.xlsx">Borko et al. - Results.xlsx</a><br> <br> 3. Graph of the overall effect of desialylation and synergistic anion on the thermodynamic parameters for the reaction of native (Tf+s) and desialylated (Tf-s) apotransferrin with FeNTA, based on the values of ∆<sub>r</sub><em>H</em>° and -<em>T</em>∆<sub>r</sub><em>S</em>°: <a href="https://zenodo.org/api/files/188f4399-e839-4710-8a28-996af05961aa/Borko%20et%20al.%20-%20dH%20vs.%20-TdS%20plot.xlsx">Borko et al. - dH vs. -TdS plot.xlsx</a></p> <p>4. Complete statistical analysis of results: <a href="https://zenodo.org/api/files/188f4399-e839-4710-8a28-996af05961aa/Borko%20et%20al.%20-%20Statistics.xlsx">Borko et al. - Statistics.xlsx </a><br> <br> a) Shapiro-Wilk test for normality of data.<br> b) Brown-Forsythe test for homogeneity of variances.<br> c) One-way and two-way ANOVA for all parameters, including Welch-James one-way ANOVA with approximate degrees of freedom and an overview of the obtained results.<br> d) Hedges' d values for effect size.<br> <br> All calculations were performed using the built-in functions in Excel 365 or the Real Statistics Resource Pack, which can be downloaded here:<br> <br> <a href="https://www.real-statistics.com/free-download/real-statistics-resource-pack/">https://www.real-statistics.com/free-download/real-statistics-resource-pack/</a><br> <br> After installation, it may be necessary to change the source of the XRealStats add-in to automatically update the calculations using the Edit Links dialogue. The location of the installed XRealStats.xlam file may need to be added to the Trusted Locations in the Excel Trust Center settings.<br> <br> 5. Welch-James Two-way ANOVA with approximate degrees of freedom performed with Rstudio (version 2022.01.1 build554) using the welchADF package for R (version 4.2.1): <a href="https://zenodo.org/api/files/188f4399-e839-4710-8a28-996af05961aa/Borko%20et%20al.%20-%20WelchADF%202-way%20ANOVA%20%28Rstudio%29.zip">Borko et al. - WelchADF 2-way ANOVA (Rstudio).zip</a><br> <br> More details about the welchADF package can be found here: <a href="https://doi.org/10.32614/RJ-2017-049">https://doi.org/10.32614/RJ-2017-049</a><br> <br> 6. UHPLC chromatograms used to assign the structures and content of N-glycans in native and desialylated apo-transferrin, including the Python script for peak integration: <a href="https://zenodo.org/api/files/188f4399-e839-4710-8a28-996af05961aa/Borko%20et%20al.%20-%20UHPLC%20chromatograms.zip">Borko et al. - UHPLC chromatograms.zip</a></p> <p>For additional details and background, please visit: <a href="https://glymech.pharma.hr//GlyMech.html">https://glymech.pharma.hr//GlyMech.html</a>.</p> <p> </p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.