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190
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ShareScore release 0.9.0
Dataset results
190 results for “Inner ear”
Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease
ClinicalTrials.gov study NCT03587701. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Healthy Subjects (HYDROPS)
ClinicalTrials.gov study NCT02529475. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Inner and Middle Ear Effects of Hyperbaric Oxygen Thrapy
ClinicalTrials.gov study NCT04186741. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Inner Ear Function in Psoriatic Patients
ClinicalTrials.gov study NCT03865030. IPD Sharing: NO. Countries: 1. Publications: 6.
Data from: Inner ear morphology of diadectomorphs and seymouriamorphs (Tetrapoda) uncovered by high‐resolution x‐ray microcomputed tomography, and the origin of the amniote crown group
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Rapid mechanical stimulation of inner-ear hair cells by photonic pressure
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Hearing from the ocean and into the river: The evolution of the inner ear of Platanistoidea (Cetacea, Odontoceti)
<p>The inner ear of the two higher clades of modern cetaceans (Neoceti) is highly adapted for hearing infrasonic (mysticetes) or ultrasonic (odontocetes) frequencies. Within odontocetes, Platanistoidea comprises a single extant riverine representative, <i>Platanista gangetica</i>, and a diversity of mainly extinct marine species from the late Oligocene onward. Recent studies, drawing on features including the disparate tympanoperiotic, have not yet provided a consensus phylogenetic hypothesis for platanistoids. Further, cochlear morphology and evolutionary patterns have never been reported. Here, we describe for the first time the inner ear morphology of late Oligocene–early Miocene extinct marine platanistoids and their evolutionary patterns. We initially hypothesized that extinct marine platanistoids lacked a specialised inner ear like <i>Platanista gangetica</i> and thus, their morphology and inferred hearing abilities were more similar to pelagic odontocetes. Our results reveal there is no "typical" platanistoid cochlear type as the group displays a disparate range of cochlear anatomies, but all are consistent with high-frequency hearing. Stem odontocete <i>Prosqualodon australis</i> and platanistoid <i>Otekaikea huata </i>present a tympanal recess in their cochlea, of yet uncertain function in the hearing mechanism in cetaceans. The more basal morphology of <i>Aondelphis talen</i> indicates it had lower high-frequency hearing than other platanistoids. Finally, <i>Platanista </i>has the most derived cochlear morphology, adding to evidence that it is an outlier within the group and consistent with a >9 Myr long separation from its sister genus <i>Zarhachis</i>. The evolution of a singular sound production morphology within Platanistidae may have facilitated the survival of <i>Platanista </i>to the present day.</p>
IE-Map: A novel in-vivo atlas and template of the human inner ear
<p>Brain atlases and templates are core tools in scientific research with increasing importance also in clinical applications. Advances in neuroimaging now allowed us to expand the atlas domain to the vestibular and auditory organ, the inner ear. In this study, we present IE-Map, an in-vivo template and atlas of the human labyrinth derived from multi-modal high-resolution magnetic resonance imaging (MRI) data, in a fully non-invasive manner without any contrast agent or radiation. We reconstructed a common template from 126 inner ears (63 normal subjects) and annotated it with 94 established landmarks and semi-automatic segmentations of all relevant macroscopic vestibular and auditory substructures. We validated the atlas by comparing MRI templates to a novel CT/micro-CT atlas, which we reconstructed from 21 publicly available post-mortem images of the bony labyrinth. Templates in MRI and micro-CT have a high overlap, and several key anatomical measures of the bony labyrinth in IE-Map are in line with micro-CT literature of the inner ear. A quantitative substructural analysis based on the new template, revealed a correlation of labyrinth parameters with total intracranial volume. No effects of gender or laterality were found. We provide the validated templates, atlas segmentations, surface meshes and landmark annotations as open-access material, to provide neuroscience researchers and clinicians in neurology, neurosurgery, and otorhinolaryngology with a widely applicable tool for computational neuro-otology.</p>
Transcriptome analysis of wild-typ and Osbpl2-/- OC1 cells/ wild-typ and osbpl2b-/- zebrafish inner ear tissues
<p>wild-typ:T01, T02, T03</p> <p>Osbpl2-/-: T04, T05, T06</p>
Figure 1 in The petrosal and inner ear of the Late Jurassic cladotherian mammal Dryolestes leiriensis and implications for ear evolution in therian mammals
Figure 1. Phylogeny of the main comparative taxa and names of major clades used in this study.
Comparative Study of Superficial Cervical Plexus Block and Nerve of Arnold Block and Incidence of PONV for Inner Ear Surgery
ClinicalTrials.gov study NCT02724033. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of a Hearing Device for Transmitting Sound to the Inner Ear
ClinicalTrials.gov study NCT05628285. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Bony labyrinth morphometry reveals hidden diversity in lungless salamanders (Family Plethodontidae): structural correlates of ecology, development, and vision in the inner ear
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Data from: The morphology of the inner ear of squamate reptiles and its bearing on the origin of snakes
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Hearing from the ocean and into the river: The evolution of the inner ear of Platanistoidea (Cetacea, Odontoceti)
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Characterization of mouse melanocytes reveals ultrastructural and immunological insights into the inner ear function
GEO Series GSE306457. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs
GEO Series GSE214099. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
RNA expression data of inner ear tissues in SOX10 p.R109W mutation pigs with inner ear malformation and wild-type pigs
GEO Series GSE110103. Sus scrofa. 5 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of the zebrafish inner ear points to growth hormone mediated regeneration following acoustic trauma
GEO Series GSE29669. Danio rerio. 9 samples. Type: Expression profiling by array.
Characterization of mouse melanocytes reveals ultrastructural and immunological insights into the inner ear function [RNA-Seq]
GEO Series GSE307045. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.