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1,391 results for “Liver cancer”
[18F]FMISO PET/CT After Transcatheter Arterial Embolization in Imaging Tumors in Patients With Liver Cancer
ClinicalTrials.gov study NCT02695628. IPD Sharing: NO. Countries: 1. Publications: 1.
Liver regeneration-associated hepatocellular YAP1 activation prevents colorectal cancer liver metastasis through glutamine competition
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Reshaping the landscape of locoregional treatments for breast cancer liver metastases: A novel, intratumoral, p21-targeted percutaneous therapy increases survival in BALB/c mice inoculated with 4T1 triple negative breast cancer cells in the liver
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Data from: Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma
The aim of the current study was to identify biomarkers that correlate with the Barcelona Clinic Liver Cancer (BCLC) staging system and prognosis of patients with hepatocellular carcinoma (HCC). We downloaded 4 gene expression datasets from the Gene Expression Omnibus database (http://www.ncbi.nlm.nih.gov/geo), and screened for genes that were differentially expressed between HCC and normal liver tissues, using significance analysis of the microarray algorithm. We used a weighted gene co-expression network analysis (WGCNA) to identify hub genes that correlate with BCLC staging, functional enrichment analysis to associate hub genes with their functions, protein-protein interaction network analysis to identify interactions among hub genes, UALCAN analysis to assess gene expression levels based on tumour stage, and survival analyses to clarify the effects of hub genes on patients' overall survival (OS). We identified 50 relevant hub genes using WGCNA; among them, 13 genes (including TIGD5, C8ORF33, NUDCD1, INSB8, and STIP1) correlated with OS and BCLC staging. Significantly enriched gene ontology biological process terms included RNA processing, non-coding RNA processing and phosphodiester bond hydrolysis, and 6 genes were found to interact with 10 or more hub genes. We identified several candidate biomarkers that correlate with BCLC staging and OS of HCC. These genes might be used for prognostic assessment and selection of HCC patients for surgery, especially those with intermediate or advanced disease.
An update on Radiomics Techniques in Primary Liver Cancers
<p>I uploaded the images of the manuscript "<strong>An update on Radiomics Techniques in Primary Liver Cancers</strong>" accepted on Infectious Agent and Cancer.</p>
Multi-region sequencing with spatial information enables accurate heterogeneity estimation and risk stratification in liver cancer
<p>We performed multi-region sampling and sequencing on 14 patients with HCC, collecting a total of 75 tumor samples with spatial information and molecular data. In addition, 21 matched adjacent liver samples were also collected. All samples were subjected to RNA sequencing (RNA-seq). RNA sequencing was performed on Illumina NovaSeq 6000 platform with 40M pair-end 150bp reads per sample. Whole-exome sequencing (WES) was performed on 36 samples from patients T10, T13 and T18 (n = 26) as well as adjacent non-tumor tissues (n = 10). Paired end, 150bp read-length sequencing was then performed on Illumina NovaSeq 6000 platform with a mean sequencing coverage of 100X. Raw sequencing data has been deposited at the National Omics Data Encyclopedia (NODE) under the accession code OEP002956 ( <a href="http://www.biosino.org/node/project/detail/OEP002956">http://www.biosino.org/node/project/detail/OEP002956</a>).</p>
Fig. 2. 1H–1H in Antitumoral activity of 1,2,4-oxadiazoles compounds isolated from the Neowerdermannia vorwerkii in liver and colon human cancer cells
Fig. 2. 1H–1H COSY and HMBC key correlations of 3-(pyridin-3-yl)-5-(tiophen-3-yl)-1,2,4-oxadiazole (1), 5-(3-methoxyphenyl)-3-(pyridin-3-yl)-1,2,4-oxadiazole (2) and 5-(3-hydroxyphenyl)-3-(pyridin-3-yl)-1,2,4-oxadiazole (3).
Fig. 1. 3 in Antitumoral activity of 1,2,4-oxadiazoles compounds isolated from the Neowerdermannia vorwerkii in liver and colon human cancer cells
Fig. 1. 3-(pyridin-3-yl)-5-(tiophen-3-yl)-1,2,4-oxadiazole (1), 5-(3-methoxyphenyl)-3-(pyridin-3-yl)-1,2,4-oxadiazole (2) and 5-(3-hydroxyphenyl)-3-(pyridin-3-yl)- 1,2,4-oxadiazole (3).
Small extrachromosomal circular DNA harboring targeted tumor suppressor gene mutations supports intratumor heterogeneity in mouse liver cancer induced by multiplexed CRISPR/Cas9
<p>These files include raw image data from our study titled "Small extrachromosomal circular DNA containing targeted tumor suppressor mutations supports intratumoral heterogeneity in multiplex CRISPR/Cas9-induced mouse liver cancer".</p>
National Liver Cancer Screening Trial
ClinicalTrials.gov study NCT06084234. IPD Sharing: NO. Countries: 1. Publications: 1.
Liver Cancer and Immunotherapy in the Liquid Biopsy Era
ClinicalTrials.gov study NCT05810402. IPD Sharing: NO. Countries: 1. Publications: 25.
Chemotherapy in Treating Children With Liver Cancer
ClinicalTrials.gov study NCT00003912. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Hepatic Arterial Infusion Plus Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver
ClinicalTrials.gov study NCT00026234. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Primary Liver Cancer Cohort of South China
ClinicalTrials.gov study NCT03297255. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Clinical Study of VG161 in Subjects with Advanced Primary Liver Cancer
ClinicalTrials.gov study NCT04806464. IPD Sharing: NO. Countries: 1. Publications: 1.
Bortezomib in Treating Patients With Advanced Cancer and Liver Dysfunction
ClinicalTrials.gov study NCT00091117. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
ClinicalTrials.gov study NCT02072486. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Thalidomide Plus Interferon Alfa in Treating Patients With Progressive Liver Cancer That Cannot be Surgically Removed
ClinicalTrials.gov study NCT00006006. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Implication of Long Non-coding RNA HOTTIP Haplotype on Liver Cancer Metastasis
ClinicalTrials.gov study NCT06544005. IPD Sharing: UNDECIDED. Countries: 1. Publications: 12.
Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases
ClinicalTrials.gov study NCT06200831. IPD Sharing: NO. Countries: 1. Publications: 3.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.