Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
86
datasets available to search
ShareScore release 0.9.0
Dataset results
86 results for “Novel Environment”
Data from: Escherichia coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity
There is considerable understanding about how laboratory populations respond to predictable (constant or deteriorating environment) selection for single environmental variables such as temperature or pH. However, such insights may not apply when selection environments comprise multiple variables that fluctuate unpredictably, as is common in nature. To address this issue, we grew replicate laboratory populations of Escherichia coli in nutrient broth whose pH and concentrations of salt (NaCl) and hydrogen peroxide (H2O2) were randomly changed daily. After ~170 generations, the fitness of the selected populations had not increased in any of the three selection environments. However, these selected populations had significantly greater fitness in four novel environments which have no known fitness-correlation with tolerance to pH, NaCl or H2O2. Interestingly, contrary to expectations, hypermutators did not evolve. Instead, the selected populations evolved an increased ability for energy-dependent efflux activity that might enable them to throw out toxins, including antibiotics, from the cell at a faster rate. This provides an alternate mechanism for how evolvability can evolve in bacteria and potentially lead to broad-spectrum antibiotic resistance, even in the absence of prior antibiotic exposure. Given that environmental variability is increasing in nature, this might have serious consequences for public health.
Data from: Sexually antagonistic genetic variance for fitness in an ancestral and a novel environment
Open the record for dataset details and reuse information.
Data from: Fluctuating temperature leads to evolution of thermal generalism and preadaptation to novel environments
Open the record for dataset details and reuse information.
Data from: Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles
Open the record for dataset details and reuse information.
Data from: Escherichia coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity
Open the record for dataset details and reuse information.
Data from: Quantitative genetics of female mate preferences in an ancestral and a novel environment
Open the record for dataset details and reuse information.
Data from: A simple genetic basis of adaptation to a novel thermal environment results in complex metabolic rewiring in Drosophila
Open the record for dataset details and reuse information.
Data from: Hormonal, behavioral, and life-history traits exhibit correlated shifts in relation to population establishment in a novel environment
Open the record for dataset details and reuse information.
Data from: Meek mothers with powerful daughters: effects of novel host environments and small trait differences on parasitoid competition
Open the record for dataset details and reuse information.
Association with a novel protective microbe facilitates host adaptation to a stressful environment
Open the record for dataset details and reuse information.
A quantitative genetics approach to cross-validate lab- versus field-based behavior in novel environments
Open the record for dataset details and reuse information.
Behavioural repertoire of high-shore littorinid snails reveals novel adaptations to an extreme environment
Open the record for dataset details and reuse information.
Data from: Genomic evidence that sexual selection impedes adaptation to a novel environment
Open the record for dataset details and reuse information.
Data from: Rapid responses of soil microorganisms improve plant fitness in novel environments
Open the record for dataset details and reuse information.
Hippocampal RNA-Seq Data and Behavioral Data from an F2 intercross of Rats Selectively-Bred to Show High or Low Levels of Locomotor Activity in a Novel Environment (bred High Responders vs. bred Low R
GEO Series GSE225746. Rattus norvegicus. 250 samples. Type: Expression profiling by high throughput sequencing.
Hippocampal RNA-Seq Data and Behavioral Data from Rats Selectively-Bred to Show High or Low Levels of Locomotor Activity in a Novel Environment (bred High Responders vs. bred Low Responders)
GEO Series GSE225744. Rattus norvegicus. 24 samples. Type: Expression profiling by high throughput sequencing.
Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression programs in the hippocampus
GEO Series GSE283483. Mus musculus. 160 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
The growth factor environment defines distinct pluripotent ground states in novel blastocyst derived stem cells
GEO Series GSE12519. Mus musculus. 3 samples. Type: Expression profiling by array.
Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments
ClinicalTrials.gov study NCT05764759. IPD Sharing: NO. Countries: 1. Publications: 0.
Use of a Novel Digital Therapeutic Intervention for the Management of Delirium in the Acute Care Environment
ClinicalTrials.gov study NCT04652622. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.