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289 results for “Phosphatase”
Search Elevated Serum Alkaline Phosphatase as a Marker of Prenatal Intervillositis Chronic Histiocytic
ClinicalTrials.gov study NCT02668120. IPD Sharing: NO. Countries: 1. Publications: 1.
Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis
ClinicalTrials.gov study NCT00430859. IPD Sharing: Not stated. Countries: 2. Publications: 10.
Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)
ClinicalTrials.gov study NCT00739505. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Gingival Crevicular Fluid Alkaline Phosphatase as Skeletal Growth Indicator
ClinicalTrials.gov study NCT04452071. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Prostatic Acid Phosphatase (PAP) Vaccine in Patients With Prostate Cancer
ClinicalTrials.gov study NCT00582140. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Safety/Efficacy Study of Bovine Intestinal Alkaline Phosphatase in Patients With Moderate to Severe Ulcerative Colitis
ClinicalTrials.gov study NCT00727324. IPD Sharing: Not stated. Countries: 2. Publications: 4.
Data from: Alkaline phosphatase, lactic dehidrogenase, inflammatory variables and apparent diffusion coefficients from MRI for prediction of chemotherapy response in osteosarcoma
<p><span><b><i>Background</i></b><b>. </b>This present study aimed to assess if clinical, laboratory and MRI were an accurate benchmark in assessing the effectiveness of neoadjuvant chemotherapy in osteosarcoma patients.<b> <i>Methods. </i></b>This was an observational analytic study with a cross-sectional design. Research subjects were selected using the total sampling method from osteosarcoma patients who underwent neoadjuvant chemotherapy during the period between January 2017– July 2019. <b><i>Results</i>.</b>Of the 58 patients included in this study, 38 were male and 20 were female aged 5 - 67 years (mean,16-year-old. 37(63.8%) patients underwent neoadjuvant chemotherapy with CAI regimens and 13 (36.2%) with CA. The tumors were classified as stage <b>IIB </b>in 43 (74.1%) patients and stage III in15 (25.9%) patients. After undergoing neoadjuvant chemotherapy, 4 patients had poor MSTS, 30 patients had fair MSTS, 17 and 7 patients had good and excellent MSTS score, respectively. Spearman's test revealed no correlation between tumor necrosis after neoadjuvant chemotherapy with a reduction in tumor size and MSTS score. Wilcoxon test showed significant differences between ALP, ESR, and NLR before and after neoadjuvant chemotherapy in the poor-response group. We found no significant difference between L<b>DH</b> and LMR before and after neoadjuvant chemotherapy in the good-response group. We had 9 patients for ADC value only. No significant statistical differences were found in tumor volumes after chemotherapy in both groups. <b><i>Conclusion.</i></b> We demonstrated that ALP level after neoadjuvant chemotherapy was markedly decreased, and was statistically significant in the poor-response group. We also demonstrated that LDH value before neoadjuvant chemotherapy had a strong correlation with degree of necrosis and could be used as a predictive indicator. NLR and LMR cannot be independent prognostic factors. MRI plays an important role in evaluating tumor volumes and preoperative radiological changes, using DWI and water diffusion to predict histological necrosis. </span></p> <p> </p> <p> </p>
Data from: Greater root phosphatase activity in nitrogen-fixing rhizobial but not actinorhizal plants with declining phosphorus availability
1. The abundance of nitrogen (N)-fixing plants in ecosystems where phosphorus (P) limits plant productivity poses a paradox because N fixation entails a high P cost. One explanation for this paradox is that the N-fixing strategy allows greater root phosphatase activity to enhance P acquisition from organic sources, but evidence to support this contention is limited. 2. We measured root phosphomonoesterase (PME) activity of 10 N-fixing species, including rhizobial legumes and actinorhizal Allocasuarina species, and eight non-N-fixing species across a retrogressive soil chronosequence showing a clear shift from N to P limitation of plant growth and representing a strong natural gradient in P availability. 3. Legumes showed greater root PME activity than non-legumes, with the difference between these two groups increasing markedly as soil P availability declined. By contrast, root PME activity of actinorhizal species was always lower than that of co-occurring legumes and not different from non-N-fixing plants. 4. The difference in root PME activity between legumes and actinorhizal plants was not reflected in a greater or similar reliance on N fixation for N acquisition by actinorhizal species compared to co-occurring legumes. 5. Synthesis. Our results support the idea that N-fixing legumes show high root phosphatase activity, especially at low soil P availability, but suggest that this is a phylogenetically conserved trait rather than one directly linked to their N-fixation capacity.
External RNA-seq dataset for manuscript entitled "Downregulated dual-specificity protein phosphatase 1 in ovarian carcinoma: a comprehensive study with multiple methods"
<p>RNA-seq dataset of ovarian cancer from TCGA and normal ovary from GTEx database</p>
External microarray datasets for manuscript entitled "Downregulated dual-specificity protein phosphatase 1 in ovarian carcinoma: a comprehensive study with multiple methods"
<p>Microarrays related to ovarian carcinoma from GEO database</p>
Fig. 3 in Oleanane hemiacetal glycosides from Gymnema latifolium and their inhibitory effects on protein tyrosine phosphatase 1B
Fig. 3. Key COSY and HMBC correlations of compounds 1, 5, 6 and 7.
Fig. 2 in Oleanane hemiacetal glycosides from Gymnema latifolium and their inhibitory effects on protein tyrosine phosphatase 1B
Fig. 2. Chemical structure of isolated compounds 1–9 isolated from Gymnema latifolium.
Fig. 2 in Azaphilones with protein tyrosine phosphatase inhibitory activity isolated from the fungus Aspergillus deflectus
Fig. 2. Key HMBC and NOESY correlations of 1.
Fig. 1 in Azaphilones with protein tyrosine phosphatase inhibitory activity isolated from the fungus Aspergillus deflectus
Fig. 1. The structures of azaphilones 1–11.
Fig. 1. Alboluteins A-C in Protein tyrosine phosphatase 1B inhibitors from the fungus Malbranchea albolutea
Fig. 1. Alboluteins A-C (1–3) isolated from M. albolutea.
Serum Alkaline Phosphatase Levels In Healthy Turkish Children
ClinicalTrials.gov study NCT06689709. IPD Sharing: NO. Countries: 0. Publications: 4.
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease
ClinicalTrials.gov study NCT04284878. IPD Sharing: NO. Countries: 0. Publications: 1.
Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma
ClinicalTrials.gov study NCT03027388. IPD Sharing: YES. Countries: 1. Publications: 0.
Data from: Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss
Open the record for dataset details and reuse information.
Data from: Greater root phosphatase activity in nitrogen-fixing rhizobial but not actinorhizal plants with declining phosphorus availability
Open the record for dataset details and reuse information.
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International Brain Laboratory public data
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.