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166
datasets available to search
ShareScore release 0.9.0
Dataset results
166 results for “Stem growth”
Human umbilical cord matrix mesenchymal stem cells suppress the growth of breast cancer by expression of tumor suppressor genes [human]
GEO Series GSE64827. Homo sapiens. 6 samples. Type: Expression profiling by array.
miR-125b: A Rheostat of Growth versus Stress-Induced MAPKs That Governs Stemness and OncomiR Addiction in Skin
GEO Series GSE54704. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Regulatory T cells in skin promote hair follicle stem cell activation and hair growth through glucocorticoid signaling (RNA-Seq)
GEO Series GSE183805. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
ANILLIN REGULATES BREAST CANCER CELL MIGRATION, GROWTH AND METASTASIS BY NON-CANONICAL MECHANISMS INVOLVING CONTROL OF CELL STEMNESS AND DIFFERENTIATION
GEO Series GSE131120. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Division-Independent Differentiation of Muscle Stem Cells During a Growth Stimulus
GEO Series GSE235102. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates
GEO Series GSE77260. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Mechanical Tension Mobilizes Lgr6+ Epidermal Stem Cells to Drive Skin Growth
GEO Series GSE186774. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing; Expression profiling by array.
Control of Paneth cell function by HuR regulates gut mucosal growth by altering stem cell activity
GEO Series GSE242410. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Clemastine suppresses proneural glioblastoma stem cell growth
GEO Series GSE186319. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Hair growth is induced by blockade of macrophage-derived oncostatin M and JAK-STAT5 signaling in hair follicle stem cells.
GEO Series GSE108709. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Intracrine Vascular Endothelial Growth Factor Maintains Hippocampal Neural Stem Cell Quiescence
GEO Series GSE220871. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
The growth factor environment defines distinct pluripotent ground states in novel blastocyst derived stem cells
GEO Series GSE12519. Mus musculus. 3 samples. Type: Expression profiling by array.
Premature aging in growth-plate and periosteum resident skeletal stem cells is responsible for bone loss
GEO Series GSE182540. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
PROX1 transcription factor is a master transcriptional regulator and essential for the stemness and growth of rhabdomyosarcoma
GEO Series GSE145171. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth
GEO Series GSE301009. Drosophila melanogaster. 2 samples. Type: Expression profiling by high throughput sequencing.
KMT9 controls growth and stemness of colorectal cancer
GEO Series GSE150506. Homo sapiens; Mus musculus. 72 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Knockdown of NAT12/NAA30 decreases glioblastoma stem cell growth and tumorigenicity by regulating hypoxia response, p-MTOR (Ser2448) and p53 pathway
GEO Series GSE60706. Homo sapiens. 12 samples. Type: Expression profiling by array.
Data from: Models of knot and stem development in black spruce trees indicate a shift in allocation priority to branches when growth is limited
The branch autonomy principle, which states that the growth of individual branches can be predicted from their morphology and position in the forest canopy irrespective of the characteristics of the tree, has been used to simplify models of branch growth in trees. However, observed changes in allocation priority within trees towards branches growing in light-favoured conditions, referred to as 'Milton's Law of resource availability and allocation,' have raised questions about the applicability of the branch autonomy principle. We present models linking knot ontogeny to the secondary growth of the main stem in black spruce (Picea mariana (Mill.) B.S.P.), which were used to assess the patterns of assimilate allocation over time, both within and between trees. Data describing the annual radial growth of 445 stem rings and the three-dimensional shape of 5,377 knots were extracted from optical scans and X-ray computed tomography images taken along the stems of 10 trees. Total knot to stem area increment ratios (KSR) were calculated for each year of growth, and statistical models were developed to describe the annual development of knot diameter and curvature as a function of stem radial increment, total tree height, stem diameter, and the position of knots along an annual growth unit. KSR varied as a function of tree age and of the height to diameter ratio of the stem, a variable indicative of the competitive status of the tree. Simulations of the development of an individual knot showed that an increase in the stem radial growth rate was associated with an increase in the initial growth of the knot, but also with a shorter lifespan. Our results provide support for 'Milton's Law,' since they indicate that allocation priority is given to locations where the potential return is the highest. The developed models provided realistic simulations of knot morphology within trees, which could be integrated into a functional-structural model of tree growth and above-ground resource partitioning.
Data from: Resting zone of the growth plate harbors a unique class of skeletal stem cells
Skeletal stem cells regulate bone growth and homeostasis by generating diverse cell types including chondrocytes, osteoblasts and marrow stromal cells. The emerging model postulates a distinct type of skeletal stem cells closely associated with the growth plate1-4, a special cartilaginous tissue playing critical roles in bone elongation5. The resting zone maintains the growth plate by expressing parathyroid hormone-related protein (PTHrP) that interacts with Indian hedgehog (Ihh) released from the hypertrophic zone6-10, while providing a source of other chondrocytes11. However, the identity of skeletal stem cells and how they are maintained in the growth plate are unknown. Here we show that skeletal stem cells are formed among PTHrP+ chondrocytes within the resting zone of the postnatal growth plate. PTHrP+ chondrocytes expressed a panel of markers for skeletal stem/progenitor cells and uniquely possessed the properties as skeletal stem cells in cultured conditions. Cell lineage analysis revealed that PTHrP+ resting chondrocytes continued to form columnar chondrocytes long term, which underwent hypertrophy and became osteoblasts and marrow stromal cells beneath the growth plate. Transit-amplifying chondrocytes in the proliferating zone, which was concertedly maintained by a forward signal from undifferentiated cells (PTHrP) and a reverse signal from hypertrophic cells (Ihh), provided instructive cues to maintain cell fates of PTHrP+ resting chondrocytes. Our findings unravel a unique somatic stem cell type that is initially unipotent and acquires multipotency at the post-mitotic stage, underscoring the malleable nature of the skeletal cell lineage. This system provides a model in which functionally dedicated stem cells and their niche are specified postnatally and maintained throughout tissue growth by a tight feedback regulation system.
Role of Hyaluronic Acid in Causing Cancer Stem Cell Growth in the Bones of Patients With Breast Cancer
ClinicalTrials.gov study NCT02331212. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.