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220
datasets available to search
ShareScore release 0.9.0
Dataset results
220 results for “Topoisomerase”
Transcriptional repression by a secondary DNA binding surface of DNA topoisomerase I safeguards against hypertranscription
GEO Series GSE207163. Homo sapiens; Mus musculus. 62 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Distinct effects of topoisomerase II inhibitors on tumor cell lines (part 2)
GEO Series GSE33625. Homo sapiens. 4 samples. Type: Expression profiling by array.
Topo-Seq application for topoisomerases binding sites identification with a single-nucleotide resolution
GEO Series GSE117186. Escherichia coli. 31 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq]
GEO Series GSE114946. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Effects of DNA topoisomerase inhibitor acriflavine on endothelial gene expression under hypoxic conditions
GEO Series GSE186297. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
DNA topoisomerase and supercoil accumulation across yeast genome
GEO Series GSE114410. Saccharomyces cerevisiae. 68 samples. Type: Genome binding/occupancy profiling by genome tiling array.
DNA topological regulation by topoisomerase IIβ-DNA-PK interaction is important for controlled hypoxia-inducible gene expression [RNA-Seq]
GEO Series GSE285698. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Topoisomerase 3B Interacts with RNAi Machinery to Promote Heterochromatin Formation and Transcriptional Silencing
GEO Series GSE119185. Drosophila melanogaster. 6 samples. Type: Expression profiling by array.
Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase
GEO Series GSE85357. Mycobacterium tuberculosis H37Ra; Mycobacterium tuberculosis H37Rv. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Bacterial type II topoisomerases cleave DNA in a species-specific manner
GEO Series GSE303783. Synthetic plasmid. 36 samples. Type: Other.
Type II topoisomerases shape multi-scale 3D chromatin folding in regions of positive supercoils
GEO Series GSE255739. Homo sapiens. 42 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing.
The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells
GEO Series GSE74212. Homo sapiens. 9 samples. Type: Expression profiling by array.
Targeting DNA topoisomerases or checkpoint kinases forces a shift in global protein homeostasis, triggering widespread protein aggregation
GEO Series GSE173940. Homo sapiens. 32 samples. Type: Expression profiling by high throughput sequencing.
Dataset of docked structures for Topoisomerases-Histone Deacetylase-Dual Targeted Quinoline-Bridged Hydroxamates as Anticancer Agents
<p>The dataset contains docking poses of inhibitors 5C and 5G in the binding site of human TopoIIα, docking poses of inhibitors 5C and 5G in the binding site of human TopoI-DNA complex, docking poses of inhibitors 5C and 5G in the binding sites of HDAC1, HDAC6 and HDAC8 and protein-protein docking poses of hTopoIIα and HDAC1. All files are provided in pdb format. </p>
M9466 in Combination With Topoisomerase 1 Inhibitors-based Regimens in Advanced Solid Tumors and Colorectal Cancer (DDRiver 511)
ClinicalTrials.gov study NCT06509906. IPD Sharing: NO. Countries: 5. Publications: 0.
Clinical Benefit of Topoisomerase Downregulation
ClinicalTrials.gov study NCT00250094. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Topoisomerase II Alpha Gene Amplification and Protein Overexpression Predicting Efficacy of Epirubicin
ClinicalTrials.gov study NCT00162812. IPD Sharing: Not stated. Countries: 1. Publications: 0.
CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance [RNA-seq]
GEO Series GSE275117. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide prediction of topoisomerase IIB binding by architectural factors and chromatin accessibility
GEO Series GSE141528. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Topoisomerase 1 Nicking-dependent HP1gamma Engagement Mediates Acute Activation of Phase-separated Enhancers
GEO Series GSE135808. Homo sapiens; Mus musculus. 167 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.