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Dataset results
79 results for “Wistar; .”
Wistar Rat
Drawing uploaded to scidraw.io on: 21 January 2020
Differential susceptibility of Wistar Kyoto and spontaneously hypertensive rats to diesel exhaust particle exposure.
GEO Series GSE9694. Rattus norvegicus. 16 samples. Type: Expression profiling by array.
SAGE profile of rat hippocampus mRNA from Wistar rats
GEO Series GSE25750. Rattus norvegicus. 1 samples. Type: Expression profiling by SAGE.
Single-cell RNA-sequencing of mesenteric artery and aorta of 16-18 week old Wistar Kyoto rats or Spontaneously hypertensive rats
GEO Series GSE149777. Rattus norvegicus. 4 samples. Type: Expression profiling by high throughput sequencing.
Chronic subacute (incl. one subchronic study) exposure of Wistar rats to (non-)carcinogenic compound
GEO Series GSE68128. Rattus norvegicus. 123 samples. Type: Expression profiling by array.
Effects of low-doses of antiandrogenic substances on Wistar Rat testes [Transcriptome analysis]
GEO Series GSE73606. Rattus norvegicus. 120 samples. Type: Expression profiling by array.
The lncRNA and mRNA microarray analysis of Specific-pathogen-free (SPF) male wistar rats
GEO Series GSE151613. Mus musculus; Rattus norvegicus. 3 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Balloon injury-induced gene expression in common carotid arteries of wistar rat
GEO Series GSE48279. Rattus norvegicus. 3 samples. Type: Expression profiling by array.
Expression data from RVLM of Wistar-Kyoko (WKY) rats and spontaneously hypertensive rats (SHR)
GEO Series GSE194325. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
Effect of 2-ITX on mRNA expression in the liver of male Wistar rats
GEO Series GSE94770. Rattus norvegicus. 44 samples. Type: Expression profiling by array.
Radiation effects on lung carcinogenesis in neonatal, juvenile, and adult Wistar rats after thoracic X-ray irradiation
GEO Series GSE78869. Rattus norvegicus. 12 samples. Type: Genome variation profiling by genome tiling array.
Microarray analysis in vessels from control rat (Wistar rat, WT) and transgenic rat (PKCbeta deletion rat, KO) with angiotensin II
GEO Series GSE272022. Rattus norvegicus. 4 samples. Type: Expression profiling by array.
Effects of low-doses of antiandrogenic substances on Wistar Rat testes
GEO Series GSE73607. Rattus norvegicus. 238 samples. Type: Non-coding RNA profiling by array; Expression profiling by array.
Effects of low-doses of antiandrogenic substances on Wistar Rat testes [miRNome analysis]
GEO Series GSE73605. Rattus norvegicus. 118 samples. Type: Non-coding RNA profiling by array.
Temporal dysregulation of cortical gene expresssion in the isolation-reared Wistar rat
GEO Series GSE19653. Rattus norvegicus. 47 samples. Type: Expression profiling by array.
Expression data of brain arteries from Wistar rats
GEO Series GSE266601. Rattus norvegicus. 13 samples. Type: Expression profiling by array.
Cardiac Effects of Rosiglitazone in Male Wistar Rats
GEO Series GSE22553. Rattus norvegicus. 62 samples. Type: Expression profiling by array.
MicroRNA expression in mandibles of Wistar and Spontaneously Hypertensive rats with periodontal disease
GEO Series GSE241787. Rattus norvegicus; synthetic construct. 12 samples. Type: Non-coding RNA profiling by array.
Electronegativity in substituted-4(H)-quinazolinones causes anxiolysis without sedative- hypnotic adverse reaction in Female wistar rats"
<p>Objectives: In the current study, we report the synthesis, characterization and neuropharmacology of quinalozinones tethered with aromatic (3a- 3i) and heteroaromatic substitution (3j, 3k and 3l) as effective anxiolytic agents. Background: Anxiety and depression are often co-morbid with neurological as well as other medical maladies. Clinically popular anxiolytics (Benzodiazepines) are accompanied by untoward sedation and other CNS depressive actions. The quinazolinone moiety is a privileged pharmacophore with a wide pharmacological spectrum. we herein report the synthesis, characterization and pharmacological evaluation of some 2-substituted quinazolinone derivatives. Methods: The synthesized compounds were characterized using 1H-NMR and TLC analysis. Behavioral analysis was performed using EPM, OFT, PIST and FST bioassay. For further justifying the therapeutic claim, we performed systemic and neurotoxicological analysis of the most potent members of the series using OECD mandated protocols. The studies advocated the compounds to have a wide therapeutic window with >1000mg/kg and >500mg/kg LD50 and NOAEL respectively. Results: The compounds with an electronegative group in the quinazolinone nucleus (3f, 3e, 3d and 3c) induces anxiolysis devoid of sedative adverse reaction. In addition, Anti-depressant efficacy of 3f, 3e, 3d and 3c observed in rodents is a result of decrease in anxiety level. It has been found that Neurotoxicology of the potent members (3f, 3e, 3d and 3c) advocates their wide therapeutic window with >1000mg/kg LD50 and >5000mg/kg NOAEL. Conclusion: Our findings in behavioral bioassays reveal that inducing an electronegative group into the Quinazolinone nucleus yields the most potent members of the series (3f, 3e, 3d and 3c). The said compounds were found to render anxiolysis and anti-depressive action without sedative-hypnotic side effects in rodent models. In summary, we state that extending the studies in clinical setting would furbish the contours of current anxiolytic therapy especially in anxiety co morbid with medical maladies.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.