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1,387 results for “acupuncture”
A Pilot Study of Acupuncture Treatment for Dysphagia
ClinicalTrials.gov study NCT00797732. IPD Sharing: NO. Countries: 1. Publications: 4.
Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer
ClinicalTrials.gov study NCT00656513. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Acupuncture for Reduction of Inflammation
ClinicalTrials.gov study NCT01937520. IPD Sharing: NO. Countries: 1. Publications: 1.
Acupuncture and Nausea/Vomiting in Pediatric Patients
ClinicalTrials.gov study NCT01417741. IPD Sharing: NO. Countries: 1. Publications: 1.
Acupuncture Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean
ClinicalTrials.gov study NCT02959840. IPD Sharing: NO. Countries: 1. Publications: 16.
An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect
ClinicalTrials.gov study NCT01079390. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Acupuncture Using Yamamoto's Method for the Treatment of Acute Nonspecific Low Back Pain
ClinicalTrials.gov study NCT01124955. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effects of Acupuncture for Senile Pruritus
ClinicalTrials.gov study NCT06506240. IPD Sharing: YES. Countries: 1. Publications: 1.
Acupuncture for Female IC/PBSyndrome and Its Effect on the Urinary Microbiome: A Randomized Controlled Trial
ClinicalTrials.gov study NCT02232282. IPD Sharing: NO. Countries: 1. Publications: 38.
Preoperative Acupuncture for Total Knee or Hip Arthroplasty
ClinicalTrials.gov study NCT06099223. IPD Sharing: NO. Countries: 1. Publications: 40.
Efficacy of Acupuncture for Shoulder Pain Based on Remote Point Selection According to the Meridians
ClinicalTrials.gov study NCT06939309. IPD Sharing: NO. Countries: 1. Publications: 7.
Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Randomized Controlled Trial
ClinicalTrials.gov study NCT02047045. IPD Sharing: YES. Countries: 0. Publications: 3.
Acupuncture on Chemotherapy-induced Peripheral Neuropathy
ClinicalTrials.gov study NCT03626220. IPD Sharing: NO. Countries: 1. Publications: 4.
Acupressure and Acupuncture as an Intervention With Children With Autism II
ClinicalTrials.gov study NCT00935701. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Laser Acupuncture for Postpartum Weight Retention
ClinicalTrials.gov study NCT02840916. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Acupuncture in the Treatment of Gulf War Illness
ClinicalTrials.gov study NCT01305811. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Acupuncture for Chemotherapy-Induced Nausea and Vomiting
ClinicalTrials.gov study NCT02195921. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Acupuncture for Pain Management During Uterine Aspiration
ClinicalTrials.gov study NCT03391986. IPD Sharing: NO. Countries: 1. Publications: 43.
acusim: a synthetic dataset for cervicocranial acupuncture points localisation
Open the record for dataset details and reuse information.
Effect of acupuncture and metformin on insulin sensitivity in women with polycystic ovary syndrome and insulin resistance: a three-armed randomized controlled trial
<p>STUDY QUESTION</p> <p>Does acupuncture improve insulin sensitivity more effectively than metformin or sham acupuncture in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR)?</p> <p>SUMMARY ANSWER</p> <p>Among women with PCOS and IR, acupuncture was not more effective than metformin or sham acupuncture in improving insulin sensitivity.</p> <p>WHAT IS KNOWN ALREADY</p> <p>Uncontrolled trials have shown that acupuncture improved insulin sensitivity with fewer side effects compared with metformin in women with PCOS and IR. However, data from randomized trials between acupuncture and metformin or sham acupuncture are lacking.</p> <p>STUDY DESIGN, SIZE, DURATION</p> <p>This was a three-armed randomized controlled trial enrolling a total of 342 women with PCOS and IR from three hospitals between November 2015 and February 2018, with a 3-month follow-up until October 2018.</p> <p>PARTICIPANTS/MATERIALS, SETTING, METHODS</p> <p>Women aged from 18 to 40 years with PCOS and homeostasis model assessment of insulin resistance (HOMA-IR) ≥2.14 were randomly assigned (n = 114 per group) to receive true acupuncture plus placebo (true acupuncture), metformin plus sham acupuncture (metformin, 0.5 g three times daily) or sham acupuncture plus placebo (sham acupuncture) for 4 months, with an additional 3-month follow-up. True or sham acupuncture was given three times per week, and 0.5 g metformin or placebo was given three times daily. The primary outcome was change in HOMA-IR from baseline to 4 months after baseline visit. Secondary outcomes included changes in the glucose AUC during an oral glucose tolerance test, BMI and side effects at 4 months after baseline visit.</p> <p>MAIN RESULTS AND THE ROLE OF CHANCE</p> <p>After 4 months of treatment, the changes of HOMA-IR were –0.5 (decreased 14.7%) in the true acupuncture group, –1.0 (decreased 25.0%) in the metformin group and –0.3 (decreased 8.6%) in the sham acupuncture group, when compared with baseline. True acupuncture is not as effective as metformin in improving HOMA-IR at 4 months after baseline visit (difference, 0.6; 95% CI, 0.1–1.1). No significant difference was found in change in HOMA-IR between true and sham acupuncture groups at 4 months after baseline visit (difference, –0.2; 95% CI, –0.7 to 0.3). During the 4 months of treatment, gastrointestinal side effects were more frequent in the metformin group, including diarrhea, nausea, loss of appetite, fatigue, vomiting and stomach discomfort (31.6%, 13.2%, 11.4%, 8.8%, 14.0% and 8.8%, respectively). Bruising was more common in the true acupuncture group (14.9%).</p> <p>LIMITATIONS, REASONS FOR CAUTION</p> <p>This study might have underestimated the sample size in the true acupuncture group with 4 months of treatment to enable detection of statistically significant changes in HOMA-IR with fixed acupuncture (i.e. a non-personalized protocol). Participants who withdrew because of pregnancy did not have further blood tests and this can introduce bias.</p> <p>WIDER IMPLICATIONS OF THE FINDINGS</p> <p>True acupuncture did not improve insulin sensitivity as effectively as metformin in women with PCOS and IR, but it is better than metformin in improving glucose metabolism (which might reduce the risk of type 2 diabetes) and has less side effects. Metformin had a higher incidence of gastrointestinal adverse effects than acupuncture groups, and thus acupuncture might be a non-pharmacological treatment with low risk for women with PCOS. Further studies are needed to evaluate the effect of acupuncture combined with metformin on insulin sensitivity in these women.</p> <p>STUDY FUNDING/COMPETING INTEREST(S)</p> <p>This work was supported by grants 2017A020213004 and 2014A020221060 from the Science and Technology Planning Project of Guangdong Province. The authors have no conflicts of interest.</p> <p>TRIAL REGISTRATION NUMBER</p> <p>Clinicaltrials.gov number: NCT02491333.</p> <p>TRIAL REGISTRATION DATE</p> <p>8 July 2015.</p> <p>DATE OF FIRST PATIENT'S ENROLLMENT</p> <p>11 November 2015.</p>
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