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1,087 results for “aneurysm”
Figure 5 in Retraction to "Protocatechuic acid attenuates cerebral aneurysm formation and progression by inhibiting TNF-alpha/Nrf-2/NF-kB-mediated inflammatory mechanisms in experimental rats".
Figure 5: Pairwise distance values for divergence within the genus CtenomYS, including interspecific (range 0.029–0.077, with an average of 0.046) and intraspecific (range = 0–0.049, with an average of 0.008) ranges and values for divergence within C. dorSaliS and between C. dorSaliS and various other members of the genus.
Figure 4 in Retraction to "Protocatechuic acid attenuates cerebral aneurysm formation and progression by inhibiting TNF-alpha/Nrf-2/NF-kB-mediated inflammatory mechanisms in experimental rats".
Figure 4: Garli tree inferred from the maximum likelihood (ML) analysis of the 1140 bp Cytb dataset, partitioned by first, second and third codon position, under the GTR + G4 + I model for the three codon positions of sequence evolution. Node values represent Garli1000 bootstrap replicate percentages (BPs).
Differences in local immune cell landscape between Q fever and atherosclerotic abdominal aortic aneurysms identified by multiplex immunohistochemistry
<p><strong>Background:</strong> Chronic Q fever is a zoonosis caused by the bacterium <em>Coxiella burnetii</em> which can manifest as infection of an abdominal aortic aneurysm (AAA). Antibiotic therapy often fails, resulting in severe morbidity and high mortality. Whereas previous studies have focused on inflammatory processes in blood, the aim of this study was to investigate local inflammation in aortic tissue.</p> <p><strong>Methods:</strong> Multiplex immunohistochemistry was used to investigate local inflammation in Q fever AAAs compared to atherosclerotic AAAs in aorta tissue specimen. Two six-plex panels were used to study both the innate and adaptive immune system.</p> <p><strong>Results: </strong>Q fever AAAs and atherosclerotic AAAs contained similar numbers of CD68<sup>+</sup> macrophages and CD3<sup>+</sup> T cells. However, in Q fever AAAs the number of CD68<sup>+</sup>CD206<sup>+</sup> M2 macrophages was increased, while expression of GM-CSF was decreased compared to atherosclerotic AAAs. Furthermore, Q fever AAAs showed an increase in both the number of CD8<sup>+</sup> cytotoxic T cells and CD3<sup>+</sup>CD8<sup>-</sup>FoxP3<sup>+</sup> regulatory T cells. Lastly, Q fever AAAs did not contain any well-defined granulomas.</p> <p><strong>Conclusions:</strong> These findings demonstrate that despite the presence of pro-inflammatory effector cells, persistent local infection with <em>C. burnetii</em> is associated with an immune suppressed micro environment.</p> <p><strong>Funding:</strong> This work was supported by SCAN consortium: European Research Area - CardioVascualar Diseases (ERA-CVD) grant [JTC2017-044] and TTW-NWO open technology grant [STW-14716].</p>
Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety and Efficacy of Cerebrolysin™ in Patients With Aneurysmal Subarachnoid Hemorrhage
ClinicalTrials.gov study NCT01787123. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms
ClinicalTrials.gov study NCT01524211. IPD Sharing: NO. Countries: 1. Publications: 1.
Paraclinoid ANeurysm Prospectively Driven ObseRvational Analysis (PANDORA) Study
ClinicalTrials.gov study NCT02553109. IPD Sharing: NO. Countries: 1. Publications: 6.
Determinants of Vasospasm and Delayed Ischemic Deficits in Aneurysmal Subarachnoid Hemorrhage
ClinicalTrials.gov study NCT02829398. IPD Sharing: NO. Countries: 1. Publications: 1.
Prediction of Abdominal Aortic Aneurysm Shrinkage After Stent-placement With Artificial Intelligence
ClinicalTrials.gov study NCT06250998. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Prospective, Single-Arm, Multicenter Study to Evaluate the Effectiveness and Safety of Endovascular Treatment in Patients With Cerebral Aneurysms Using P64 and P48 Flow-Diverter Stents
ClinicalTrials.gov study NCT06201598. IPD Sharing: NO. Countries: 1. Publications: 16.
Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
ClinicalTrials.gov study NCT00339053. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Endovascular Treatment of TAAA and Aortic Arch Aneurysms Using Fenestrated and Branched Stent Grafts
ClinicalTrials.gov study NCT02323581. IPD Sharing: Not stated. Countries: 1. Publications: 26.
Prevention of Colon Ischemia During Aortic Aneurysm (AAA) Repair
ClinicalTrials.gov study NCT00671203. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Barrow Ruptured Aneurysm Trial
ClinicalTrials.gov study NCT01593267. IPD Sharing: NO. Countries: 1. Publications: 12.
Metabolomic Profile and Proteasic Activity as Biomarkers for Early Detection of Arterial Vasospas in Arterial Vasospasm After Aneurysmal Subarachnoid Hemorrhage
ClinicalTrials.gov study NCT02397759. IPD Sharing: Not stated. Countries: 1. Publications: 2.
STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft
ClinicalTrials.gov study NCT00111176. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Remote Ischemic Conditioning in Aneurysmal SAH
ClinicalTrials.gov study NCT06032533. IPD Sharing: YES. Countries: 1. Publications: 2.
Application of Linkage Analysis in the Identification of Novel Hereditary Factors in Familial Aneurysms
ClinicalTrials.gov study NCT06783803. IPD Sharing: NO. Countries: 1. Publications: 2.
Treatment of Unruptured Intracranial Aneurysms in China
ClinicalTrials.gov study NCT03133598. IPD Sharing: NO. Countries: 1. Publications: 1.
Fibroblasts and Thoracic Aortic Aneurysms: in Vitro Characterization in With Marfan Syndrome and Genetic Aortic Diseases
ClinicalTrials.gov study NCT06786754. IPD Sharing: NO. Countries: 1. Publications: 3.
Brain Low-risk Aneurysm Stereotactic Radiosurgical Trial
ClinicalTrials.gov study NCT06047951. IPD Sharing: NO. Countries: 1. Publications: 25.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.