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330
datasets available to search
ShareScore release 0.9.0
Dataset results
330 results for “anticancer”
A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activ
ClinicalTrials.gov study NCT06052306. IPD Sharing: NO. Countries: 8. Publications: 1.
Immune Cells Role in Lung Cancer and Their Use in Anticancer Immunotherapies and Inflammatory Lung Disease
ClinicalTrials.gov study NCT07384897. IPD Sharing: NO. Countries: 1. Publications: 5.
Granisetron Transdermal Patch for Prophylaxis of Nausea and Vomiting in Patients Receiving Oral Anticancer Agents
ClinicalTrials.gov study NCT04472143. IPD Sharing: NO. Countries: 1. Publications: 2.
Combined Anticancer Treatment of Advanced Colon Cancer
ClinicalTrials.gov study NCT01540344. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Identification of Anticancer Drugs Associated With Cancer Therapy-related Cardiac Dysfunction: a Pharmacovigilance Study
ClinicalTrials.gov study NCT06268535. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Mobile Application to Assist Adherence to Oral Anticancer Agents and Symptom Management
ClinicalTrials.gov study NCT04626830. IPD Sharing: NO. Countries: 1. Publications: 1.
Anticancer Activity of Nicotinamide on Lung Cancer
ClinicalTrials.gov study NCT02416739. IPD Sharing: NO. Countries: 1. Publications: 18.
Reporting, Evaluating, Preventing and Treating the Cardiotoxicity Induced by Anticancer Drugs During a Specific Cardio-oncology Consult and Follow up in Routine Care
ClinicalTrials.gov study NCT03882580. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Study of Oral Rucaparib With Other Anticancer Agents in Metastatic Castration Resistant Prostate Cancer Patients (RAMP)
ClinicalTrials.gov study NCT04179396. IPD Sharing: YES. Countries: 1. Publications: 0.
Collaborative Network to Take Responsibility for Oral Anticancer Therapy
ClinicalTrials.gov study NCT02861209. IPD Sharing: NO. Countries: 1. Publications: 1.
Evaluation of Clinical Safety of Combining Metformin With Anticancer Chemotherapy
ClinicalTrials.gov study NCT01442870. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With L
ClinicalTrials.gov study NCT05081609. IPD Sharing: NO. Countries: 10. Publications: 1.
Irradiation Modulates the Pharmacokinetics of Anticancer Drugs for Head and Neck Cancer
ClinicalTrials.gov study NCT01609114. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)
ClinicalTrials.gov study NCT04914897. IPD Sharing: YES. Countries: 11. Publications: 0.
Data from: Joining up the scattered anticancer knowledge on auraptene and umbelliprenin: A meta-analysis
Open the record for dataset details and reuse information.
Synthesis and in vitro anticancer activities of substituted N-(4'-Nitrophenyl)-L-prolinamides
<p>Prolinamides are present in secondary metabolites and have wide-ranging biological properties as well as antimicrobial and cytotoxic activities.</p> <p><i>N</i>-(4'-substituted phenyl)-<b>L</b>-prolinamides <b>4a</b>–<b>4w</b> were synthesised in two steps, starting from the condensation of <i>p</i>-fluoronitrobenzene <b>1a</b>–<b>1b</b> with <b>L</b>-proline <b>2a</b>–<b>2b</b>, under aqueous–alcoholic basic conditions to afford <i>N</i>-aryl-<b>L</b>-prolines <b>3a</b>–<b>3c</b>, which underwent amidation via a two-stage, one-pot reaction involving SOCl<sub>2</sub> and amines, to furnish <b>L</b>-prolinamides in 20–80% yield.</p> <p>The cytotoxicities of <b>4a</b>–<b>4w</b> against four human carcinoma cell lines (SGC7901, HCT-116, HepG2 and A549) were evaluated by MTT assay; with good tumour inhibitory activities (79.50 ± 1.24%–50.04 ± 1.45%) against HepG2. <b>4a</b> exhibited the best antitumour activity against A549 with % cell inhibition of 95.41 ± 0.67% at 100 µM. Likewise, <b>4s</b> (70.13 ± 3.41%) and<b> 4u</b> (83.36 ± 1.70%) displayed stronger antineoplastic potencies against A549 than the standard, 5-fluorouracil (64.29 ± 2.09%) whereas <b>4a</b> (93.33 ± 1.36%) and <b>4u</b> (81.29 ± 2.32%) outperformed the reference (81.20 ± 0.08%) against HCT-116. SGC7901 showed lower % cell viabilities with <b>4u</b> (8.02 ± 1.54%) and <b>4w</b> (27.27 ± 2.38%). These results underscore the antiproliferative efficacies of <b>L</b>-prolinamides whilst exposing <b>4a</b> and <b>4u</b> as promising broad-spectrum anticancer agents. SAR studies are discussed.</p>
Supplementary material for "Compounds with antiviral, anti-inflammatory and anticancer activity identified in wine via high resolution mass spectrometry and bioinformatics analyses"
<p>Wine contains a variety of molecules with potential beneficial effects on human health. Our aim was to examine the wine components with high-resolution mass spectrometry including high-resolution tandem mass spectrometry in two wine types made from grapes with or without the fungus <em>Botrytis cinerea</em>, or “noble rot.” For LC-MS/MS analysis, 12 wine samples (7 without and 5 with noble rotting) from 4 different wineries were used and wine components were identified and quantified. Results: 288 molecules were identified in the wines and the amount of 169 molecules was statistically significantly different between the two wine types. A database search was carried out to find the molecules, which were examined in functional studies so far, with high emphasis on molecules with antiviral, anti-inflammatory and anticancer activities. Conclusions: A comprehensive functional dataset related to identified wine components is also provided highlighting the importance of components with potential health benefits.</p>
Supplementary material 2 from: Abdullah AH, Alarareh AK, Al-Sha'er MA, Habashneh AY, Awwadi FF, Bardaweel SK (2024) Docking, synthesis, and anticancer assessment of novel quinoline-amidrazone hybrids. Pharmacia 71: 1-12. https://doi.org/10.3897/pharmacia.71.e117192
Scanned IR, 1H NMR and 13C NMR spectra of all new compounds
Supplementary material 1 from: Abdullah AH, Alarareh AK, Al-Sha'er MA, Habashneh AY, Awwadi FF, Bardaweel SK (2024) Docking, synthesis, and anticancer assessment of novel quinoline-amidrazone hybrids. Pharmacia 71: 1-12. https://doi.org/10.3897/pharmacia.71.e117192
Docking, synthesis, and anticancer assessment of novel quinoline-amidrazone hybrids
Figure 7 from: Abdullah AH, Alarareh AK, Al-Sha'er MA, Habashneh AY, Awwadi FF, Bardaweel SK (2024) Docking, synthesis, and anticancer assessment of novel quinoline-amidrazone hybrids. Pharmacia 71: 1-12. https://doi.org/10.3897/pharmacia.71.e117192
Figure 7 A. Diagram of receptor-ligand interaction between compound (10d) and c-Abl kinase (PDB code: 1IEP); B. 3D diagram of receptor-ligand interaction between compound (10d) c-Abl kinase enzyme (PDB code: 1IEP).
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.