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821 results for “anticoagulant”
Figure 1 in Leech anticoagulants are ancestral and likely to be multifunctional
Figure 1. Diversity of transcripts putatively related to bloodfeeding in the transcriptomes of non-bloodfeeding hirudineans and non-leech relatives. Transcript diversity is shown as a percentage, followed by their protein family name and the percentage of transcripts in parenthesis. Blue areas belong to contigs with BLAST hits against non-archetypal leech anticoagulants; red areas represent contigs with BLAST hits against archetypal anticoagulants.
Figure 2 in Leech anticoagulants are ancestral and likely to be multifunctional
Figure 2. Best-scoring maximum likelihood trees resulting from the analysis of destabilase (A; log likelihood [ln L] = −8230.744), manillase (B; ln L = −27279.363), saratin and leech antiplatelet protein (LAPP) (C; ln L = −4758.748) and cystatin (D; ln L = −2474.943) datasets. Branches drawn in black represent non-leech lineages; branches in red represent bloodfeeding leech lineages; branches in blue represent non-bloodfeeding leech lineages. Red boxes represent putative orthologues of archetypal leech anticoagulants. For the remaining gene trees, see the Supporting Information (Fig. S1).
Analysis of the effectiveness and safety of conventional anticoagulants in preventing deep vein thrombosis after total knee arthroplasty in patients undergoing total knee arthroplasty at high altitudes
<p><strong><span>Analysis of the effectiveness and safety of conventional anticoagulants in preventing deep vein thrombosis after total knee arthroplasty in patients undergoing total knee arthroplasty at high altitudes</span></strong></p>
High rates of anticoagulant rodenticide exposure in California Barred Owls
<p>Pesticide use is pervasive and the exposure of non-target wildlife has been well documented over the past half century. Among pesticides, anticoagulant rodenticides (AR) have emerged as a particularly important threat in forests of the western United States, with exposure and mortality reported for several species of conservation concern. To further quantify this threat, we collected specimens of Barred Owls (<i>Strix varia</i>) and Barred Owl x Spotted Owl hybrids from the Klamath and Cascade Mountains and Sierra Nevada in California, USA to use as indicator species for environmental contamination with AR and to infer exposure of closely related and ecologically similar Northern and California Spotted Owls (<i>S. occidentalis caurina, and S. o. occidentalis, </i>respectively). We tested 115 Barred Owl and 12 Barred Owl x Spotted Owl hybrid livers for eight AR compounds and found high rates of exposure (62%) across our study area, and greater than previous studies in the Pacific Northwest. In addition, we sampled seven ovaries from seven females and 100% tested positive for AR. Female Barred Owls were more likely than males to be exposed (78% and 50%, respectively). Unlike previous studies, we found no clear link between illegal cannabis cultivation and AR exposure. However, Barred Owls sampled in proximity to the wildland-urban interface (WUI) were more likely to be exposed to AR. Though the exact source (e.g., cannabis cultivation or application around human dwellings) and location is unknown, the association of AR exposure with the WUI was supported from GPS data from Barred Owls, Northern and California Spotted Owls, and hybrids using the WUI for foraging. The high rate of AR exposure in Barred Owls and hybrids provides mounting evidence of an additional stressor that ARs may pose to Spotted Owls – including the first evidence for California Spotted Owls – and fauna native to western forest ecosystems.</p>
Anticoagulation and Activation - Comparison in Continuous Renal Replacement Therapy
ClinicalTrials.gov study NCT01276392. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Evaluation of Complication Rates Using Filter vs. Centrifuge and Heparin vs. Citrate Anticoagulation
ClinicalTrials.gov study NCT04351438. IPD Sharing: NO. Countries: 1. Publications: 8.
Monotherapy Anticoagulation To Expedite Home Treatment of Venous Thromboembolism
ClinicalTrials.gov study NCT03404635. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Intermediate-dose vs Standard Prophylactic Anticoagulation and Statin vs Placebo in ICU Patients With COVID-19
ClinicalTrials.gov study NCT04486508. IPD Sharing: NO. Countries: 1. Publications: 6.
Better Outcomes for Anticoagulation Treatment Through Observation of Atrial Rhythm
ClinicalTrials.gov study NCT03515083. IPD Sharing: NO. Countries: 1. Publications: 10.
Optimal Anticoagulation for Higher Risk Patients Post-Catheter Ablation for Atrial Fibrillation Trial
ClinicalTrials.gov study NCT02168829. IPD Sharing: UNDECIDED. Countries: 6. Publications: 1.
Regional Anticoagulation of Dialysis Circuits With a Calcium-free Citrate-containing Dialysate
ClinicalTrials.gov study NCT03842657. IPD Sharing: NO. Countries: 1. Publications: 1.
Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress
ClinicalTrials.gov study NCT03968393. IPD Sharing: UNDECIDED. Countries: 18. Publications: 0.
Safety and Efficacy of Therapeutic Anticoagulation on Clinical Outcomes in Hospitalized Patients With COVID-19
ClinicalTrials.gov study NCT04377997. IPD Sharing: NO. Countries: 1. Publications: 20.
Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection
ClinicalTrials.gov study NCT04508439. IPD Sharing: NO. Countries: 1. Publications: 1.
Citrate-based Regional Anticoagulation Versus Heparin for Continuous Renal Replacement Therapy
ClinicalTrials.gov study NCT01269112. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Vitamin K Antagonist Versus Direct Oral Anticoagulant Treatments in Hemophilia
ClinicalTrials.gov study NCT05804734. IPD Sharing: NO. Countries: 1. Publications: 7.
Outpatient Treatment of Low-Risk Venous Thromboembolism With Target Specific Anticoagulant
ClinicalTrials.gov study NCT02079584. IPD Sharing: NO. Countries: 1. Publications: 3.
Citrate Versus Heparin Anticoagulation in Continuous Venovenous Hemofiltration
ClinicalTrials.gov study NCT00209378. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Pharmacokinetics and Point of Care Testing of Direct Oral Anticoagulants Subjects
ClinicalTrials.gov study NCT05491460. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Anticoagulation Therapy in Non-device-related Intra-cardiac Thrombus
ClinicalTrials.gov study NCT05825573. IPD Sharing: NO. Countries: 2. Publications: 1.
ScienceDex guides
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International Brain Laboratory public data
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OpenNeuro
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