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71 results for “bacterial production”
Data from: Individual- versus group-optimality in the production of secreted bacterial compounds
How unicellular organisms optimize the production of compounds is a fundamental biological question. While it is typically thought that production is optimized at the individual-cell level, secreted compounds could also allow for optimization at the group level, leading to a division of labor where a subset of cells produces and shares the compound with everyone. Using mathematical modelling, we show that the evolution of such division of labor depends on the cost function of compound production. Specifically, for any trait with saturating benefits, linear costs promote the evolution of uniform production levels across cells. Conversely, production costs that diminish with higher output levels favor the evolution of specialization – especially when compound shareability is high. When experimentally testing these predictions with pyoverdine, a secreted iron-scavenging compound produced by Pseudomonas aeruginosa, we found linear costs and, consistent with our model, detected uniform pyoverdine production levels across cells. We conclude that for shared compounds with saturating benefits, the evolution of division of labor is facilitated by a diminishing cost function. More generally, we note that shifts in the level of selection from individuals to groups do not solely require cooperation, but critically depend on mechanistic factors, including the distribution of compound synthesis costs.
Latitudinal variations in leaf bacterial functions majorly affect the biomass production of a submerged macrophytes
<p><span>Although microbial biogeography has been extensively explored in free-living communities, our understanding of the large-scale latitudinal diversity patterns of host-associated bacteria remained limited in freshwater ecosystems. To fill this knowledge gap, we conducted a field survey spanning a 2,800 km transect along a latitudinal gradient and explored the composition and structure of bacterial communities on the surfaces of <em>Myriophyllum spicatum</em>. </span></p>
Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease
ClinicalTrials.gov study NCT06548399. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer
ClinicalTrials.gov study NCT06616597. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Individual- versus group-optimality in the production of secreted bacterial compounds
Open the record for dataset details and reuse information.
A stress sensor IRE1α is required for bacterial exotoxin-induced interleukin-1β production in tissue-resident macrophages
GEO Series GSE228915. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
TPL-2;ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I interferon production
GEO Series GSE47674. Mus musculus. 158 samples. Type: Expression profiling by array.
Gene editing of the E3 ligase PIRE1 fine-tunes ROS production for enhanced bacterial disease resistance in tomato.
<p>Original data and images for figures and quantification in this manuscript.</p>
Differences in major bacterial taxa in three high Arctic soils lead to different CO2 production rates
GEO Series GSE24800. Archaea; environmental samples; environmental samples; environmental samples; Bacteria; environmental samples; environmental samples; environmental samples. 20 samples. Type: Other.
Homeostatic pockets of interferon lambda-stimulated gene production in the intestine are associated with localized exposure to bacterial microbiota
GEO Series GSE269701. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Suppression of mitochondrial energy production by peptide from photosynthetic bacterial protein inhibits tumor growth
GEO Series GSE285854. Homo sapiens. 12 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.