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1,237 results for “cell characterization”
Characterization of Circulating Tumor Cells (CTC-s) in Patients With Locally Advanced or Metastatic Stage IV Breast Cancer
ClinicalTrials.gov study NCT01048918. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Characterization of Breg Cells
ClinicalTrials.gov study NCT02615951. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Enumeration and Molecular Characterization of Circulating Tumour Cells in Women With Metastatic Breast Cancer
ClinicalTrials.gov study NCT01322893. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System
ClinicalTrials.gov study NCT05437679. IPD Sharing: NO. Countries: 1. Publications: 2.
Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease
ClinicalTrials.gov study NCT04983654. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Identification and Characterization of SARS-CoV-2 Specific CD8 T Cells in Humans
ClinicalTrials.gov study NCT04565067. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Characterization of Autoreactive Regulatory and Conventional CD4 T Cells in Recent Onset Type 1 Diabetes and Control Individuals
ClinicalTrials.gov study NCT06427421. IPD Sharing: NO. Countries: 1. Publications: 18.
Molecular Characterization and Outcomes of Aggressive B-Cell Lymphomas.
ClinicalTrials.gov study NCT07181785. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Establishment and Characterization of Patient-Derived Non-Small Cell Lung Cancer Xenografts and Cell Cultures
ClinicalTrials.gov study NCT01130571. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Intestinal Stem Cells Characterization
ClinicalTrials.gov study NCT02874365. IPD Sharing: NO. Countries: 1. Publications: 2.
Integrative Molecular Characterization Of MiT Family Translocation Renal Cell Carcinomas (IMCOR)
ClinicalTrials.gov study NCT05456074. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Morphological Parameters of Blood Cell's Activation in Characterization and Prognosis in a COPD Patients Cohort
ClinicalTrials.gov study NCT04923360. IPD Sharing: NO. Countries: 1. Publications: 22.
Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells
ClinicalTrials.gov study NCT04628806. IPD Sharing: YES. Countries: 1. Publications: 1.
Characterization and mutagenesis of Chinese hamster ovary cells endogenous retroviruses to inactivate viral particle release
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Metadata for the characterization of Platynereis dumerilii cephalic and non-cephalic sensory cell types
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Data from: A single 17D Yellow Fever vaccination provides lifelong immunity; characterization of Yellow-Fever-specific neutralizing antibody and T-cell responses after vaccination
Introduction: Prompted by recent amendments of Yellow Fever (YF) vaccination guidelines from boost to single vaccination strategy and the paucity of clinical data to support this adjustment, we used the profile of the YF-specific CD8+ T-cell subset profiles after primary vaccination and neutralizing antibodies as a proxy for potentially longer lasting immunity. Methods and Findings: PBMCs and serum were collected in six individuals on days 0, 3, 5, 12, 28 and 180, and in 99 individuals >10 years after YF-vaccination. Phenotypic characteristics of YF- tetramer+ CD8+ T-cells were determined using class I tetramers. Antibody responses were measured using a standardized plaque reduction neutralization test (PRNT). Also, characteristics of YF-tetramer positive CD8+ T-cells were compared between individuals who had received a primary- and a booster vaccination. YF-tetramer+ CD8+ T-cells were detectable on day 12 (median tetramer+ cells as percentage of CD8+ T-cells 0.2%, range 0.07–3.1%). On day 180, these cells were still present (median 0.06%, range 0.02–0.78%). The phenotype of YF-tetramer positive CD8+ T-cells shifted from acute phase effector cells on day 12, to late differentiated or effector memory phenotype (CD45RA-/+CD27-) on day 28. Two subsets of YF-tetramer positive T-cells (CD45RA+CD27- and CD45RA+CD27+) persisted until day 180. Within all phenotypic subsets, the T-bet: Eomes ratio tended to be high on day 28 after vaccination and shifted towards predominant Eomes expression on day 180 (median 6.0 (day 28) vs. 2.2 (day 180) p = 0.0625), suggestive of imprinting compatible with long-lived memory properties. YF-tetramer positive CD8+ T-cells were detectable up to 18 years post vaccination, YF-specific antibodies were detectable up to 40 years after single vaccination. Booster vaccination did not increase titers of YF-specific antibodies (mean 12.5 vs. 13.1, p = 0.583), nor induce frequencies or alter phenotypes of YF-tetramer+ CD8+ T-cells. Conclusion: The presence of a functionally competent YF-specific memory T-cell pool 18 years and sufficient titers of neutralizing antibodies 35–40 years after first vaccination suggest that single vaccination may be sufficient to provide long-term immunity.
Characterization of molecular toolkits for the control of gene expression in E. coli and E. coli-based cell-free expression system
<p>This dataset shows the characterization of 4 genetic elements designed to control gene expression in prokaryotic systems. DNA sequences carrying inducible promoters were rationally designed based on existing regulatory elements. Through fluorescent reporters, gene expression in the presence and absence of small regulatory molecules was followed over a time frame of 20 hours. The kinetics were followed in two settings: <i>in vivo</i> within <i>E. col</i>i cells and <i>in vitro</i> using cell-free systems derived from <i>E. coli</i> cell extracts. Finally, possible interferences among regulatory elements were evaluated following the expression of paired transcription and translation units carrying two different reporter genes under the control of different regulatory elements.</p>
Electrochemical Characterization and Modelling of Anode and Electrolyte Supported Solid Oxide Fuel Cells
<p>Datasets from the paper: "Electrochemical Characterization and Modelling of Anode and Electrolyte Supported Solid Oxide Fuel Cells", Front. Energy Res., 27 September 2021.</p> <p>The work was carried out within the framework of the European Project AD ASTRA. This project has received funding from the Fuel Cells and Hydrogen 2 Joint Undertaking under <strong>Grant Agreement No 825027</strong>. This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme and Hydrogen Europe.</p>
Degradation of Ni-YSZ and Ni-GDC fuel cells after 1000 h operation: Analysis of different overpotential contributions according to electrochemical and microstructural characterization
<p>Datasets from the paper:</p> <p>"Degradation of Ni-YSZ and Ni-GDC fuel cells after 1000 h operation: Analysis of different overpotential contributions according to electrochemical and microstructural characterization". E3S Web of Conferences <strong>334</strong>, 04011 (2022).</p> <p>The activity was carried out within the framework of the European Project AD ASTRA. This project has received funding from the Fuel Cells and Hydrogen 2 Joint Undertaking under <strong>Grant Agreement No 825027</strong>. This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme and Hydrogen Europe.</p>
Reanalysis of Single-Cell Sequencing Data from Healthy and Periodontitis Patients: Characterization of Oral Epithelial Cells
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.