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322
datasets available to search
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Dataset results
322 results for “chronic stress”
Contribution of Online Stress and Pain Mindfulness Treatment to ACT Process Change and Outcomes in Chronic Pain
ClinicalTrials.gov study NCT05498454. IPD Sharing: Not stated. Countries: 1. Publications: 29.
Evaluating Pathophysiological Mechanisms of Acute and Chronic Heat Stress on Maternal and Fetal Health
ClinicalTrials.gov study NCT07326176. IPD Sharing: NO. Countries: 1. Publications: 2.
Mindfulness-based Stress Reduction (MBSR) for Reduction of Chronic Pain and Drug Therapie
ClinicalTrials.gov study NCT05843409. IPD Sharing: NO. Countries: 1. Publications: 1.
Effectiveness of Cognitive Behavioral Treatment and Mindfulness Based Stress Reduction (MBSR) for Chronic Low Back Pain
ClinicalTrials.gov study NCT00360802. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Oxidative Stress in Chronic Kidney Disease: Diet and Exercise
ClinicalTrials.gov study NCT01150851. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Noradrenergic and Stress-Related Etiologies of Chronic Fatigue Syndrome
ClinicalTrials.gov study NCT03029377. IPD Sharing: NO. Countries: 1. Publications: 3.
Effects of Treatment of Chronic Stress in Patients With Lupus
ClinicalTrials.gov study NCT00483613. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Fetal Biomarkers of Chronic Maternal Stress During Pregnancy
ClinicalTrials.gov study NCT03389178. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Depression, anxiety and stress in chronic otitis media
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Data from: Gene expression under chronic heat stress in populations of the mustard hill coral (Porites astreoides) from different thermal environments
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Data from: Food restriction and chronic stress alter energy use and affect immunity in an infrequent feeder
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Data from: The insensitive dormouse: reproduction skipping is not caused by chronic stress in Glis glis
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Data from: Epistasis and maternal effects in experimental adaptation to chronic nutritional stress in Drosophila
Based on ecological and metabolic arguments some authors predict that adaptation to novel, harsh environments should involve alleles showing negative (diminishing return) epistasis and/or that it should be mediated in part by evolution of maternal effects. While the first prediction has been supported in microbes, there has been little experimental support for either prediction in multicellular eukaryotes. Here we use a line-cross design to study the genetic architecture of adaptation to chronic larval malnutrition in a population of Drosophila melanogaster which evolved on an extremely nutrient-poor larval food for 84 generations. We assayed three fitness-related traits (developmental rate, adult female weight and egg-to-adult viability) under the malnutrition conditions in 14 crosses between this selected population and a non-adapted control population originally derived from the same base population. All traits showed a pattern of negative epistasis between alleles improving performance under malnutrition. Furthermore, evolutionary changes in maternal traits accounted for half of the 68 % increase in viability and for the whole of 8 % reduction in adult female body weight in the selected population (relative to unselected controls). These results thus support both of the above predictions and point to the importance of non-additive effects in adaptive microevolution.
Data from: Cover, not caging, influences chronic physiological stress in a ground-nesting bird
Predator exclosures ('nest cages') around nests are increasingly used to enhance hatching success of declining ground-nesting birds. However, such exclosures are contentious and have been suggested to have detrimental effects on the species which they aim to protect. This study examines whether exclosures increase physiological stress of incubating birds, a hitherto unrecognised and untested potential drawback of exclosures. Red-capped plover Charadrius ruficapillus hatching success was radically altered and significantly higher for nests with exclosures (96.2%) compared with those without (6.8%). Chronic physiological stress in parents (as measured by the heterophil/lymphocyte [H/L] ratio in blood) did not vary between nests with and without exclosures, or between the sexes. However the absence of vegetative cover at the nest site was associated with a 62.7% elevation in H/L ratio, indicating that incubating birds which place their nests in the open are subject to increased levels of chronic stress. The results from this study demonstrate the fundamental importance of predation for the nesting success of this species and confirm that chronic stress levels are not a detrimental side effect of exclosure use.
Data from: Geographic variation in corticosterone response to chronic predator stress in tadpoles
Chronic stress often affects growth and development negatively and these effects are often mediated via glucocorticoid hormones, which elevate during stress. We investigated latitudinal variation in corticosterone (CORT)-response to chronic predator stress in Rana temporaria tadpoles along a 1500 km latitudinal cline in Sweden tadpoles, in a laboratory experiment. We hypothesised that more time-constrained high-latitude populations have evolved a lower CORT-response to chronic stress to maintain higher growth under stressful conditions. Southern tadpoles had higher CORT-content in response to predators after one day of exposure, whereas there was no increase in CORT in the northern populations. Two weeks later there were no predator-induced CORT elevations. Artificially elevated CORT levels strongly decreased growth, development and survival in both northern and southern tadpoles. We suggest that the lower CORT-response in high-latitude populations can be connected with avoidance of CORT-mediated reduction in growth and development, but also discuss other possible explanations.
Impact of chronic psychological stress on platelet membrane fatty acid composition in type 1 diabetes mellitus
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Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress
ClinicalTrials.gov study NCT02742532. IPD Sharing: NO. Countries: 1. Publications: 0.
Targeting Oxidative Stress in Chronic Beryllium Disease
ClinicalTrials.gov study NCT01088243. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Integrated Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)
ClinicalTrials.gov study NCT00127413. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Neurobiological Mechanisms of Stress in Youth With Chronic Widespread Pain
ClinicalTrials.gov study NCT04488757. IPD Sharing: YES. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.