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743 results for “clone”
FIGURE 14 in Laboratory Hybridization among North American Whiptail Lizards, Including Aspidoscelis inornata arizonae × A. tigris marmorata (Squamata: Teiidae), Ancestors of Unisexual Clones in Nature
FIGURE 14. Volume of the adrenal gland compared to the snout-vent length (SVL)
FIGURE 17 in Laboratory Hybridization among North American Whiptail Lizards, Including Aspidoscelis inornata arizonae × A. tigris marmorata (Squamata: Teiidae), Ancestors of Unisexual Clones in Nature
FIGURE 17. Mesonephros of laboratory hybrid
FIGURE 10 in Laboratory Hybridization among North American Whiptail Lizards, Including Aspidoscelis inornata arizonae × A. tigris marmorata (Squamata: Teiidae), Ancestors of Unisexual Clones in Nature
FIGURE 10. Testis, adrenal gland,
FIGURE 4 in Laboratory Hybridization among North American Whiptail Lizards, Including Aspidoscelis inornata arizonae × A. tigris marmorata (Squamata: Teiidae), Ancestors of Unisexual Clones in Nature
FIGURE 4. Three Aspidoscelis of
FIGURE 3 in Laboratory Hybridization among North American Whiptail Lizards, Including Aspidoscelis inornata arizonae × A. tigris marmorata (Squamata: Teiidae), Ancestors of Unisexual Clones in Nature
FIGURE 3. Parents of the Aspidoscelis hybrids
FIGURE 16 in Laboratory Hybridization among North American Whiptail Lizards, Including Aspidoscelis inornata arizonae × A. tigris marmorata (Squamata: Teiidae), Ancestors of Unisexual Clones in Nature
FIGURE 16. The testis of laboratory
Data - Attack of the clones: population genetics reveals clonality of Colletotrichum lupini, the causal agent of lupin anthracnose
<p><em>Colletotrichum lupini</em>, causing lupin anthracnose, is one of the worst pathogens to lupin cultivation worldwide. Understanding its population structure and evolutionary potential is crucial to design successful disease management strategies. The objective of this study was to employ population genetics to investigate the genetic diversity, evolutionary dynamics and molecular basis of host-speciation of this notorious lupin pathogen. A collection of globally representative <em>C. lupini </em>isolates was genotyped through triple digest restriction-site associated DNA sequencing (3D-RADseq), resulting in a dataset of unparalleled resolution. Phylogenetic and structural analysis could distinguish four (I – IV) independent lineages. The strong population structure, low recombination rate and slow linkage decay strongly indicate that <em>C. lupini</em> reproduces clonally. Different morphologies and virulence patterns on white and Andean lupin were observed between and within clonal lineages. Lineage II isolates were shown to have a mini chromosome which was also partly present in lineage III and IV, but not in lineage I isolates. Variation in the presence of this mini-chromosome could indicate a function related to virulence or host-speciation. All four lineages were present in the South American Andes region, which is concluded to be the center of origin of this species. Only members of lineage II have been found outside South America since the 1990s, indicating it as the current pandemic population. As a seed-borne pathogen, <em>C. lupini</em> has mainly spread through infected but symptomless seeds, stressing the importance of phytosanitary measures to prevent future outbreaks of strains that are yet confined to South America.</p>
The maternal effects of dietary restriction on Dnmt expression and reproduction in two clones of Daphnia pulex
<p>The inheritance of epigenetic marks induced by environmental variation in a previous generation is broadly accepted as a mediator of phenotypic plasticity. Transgenerational effects linking maternal experiences to changes in morphology, gene expression, and life history of successive generations are known across many taxa. While the number of studies linking epigenetic variation to ecological maternal effects is increasing rapidly, few if any attempts have been made to investigate molecular mechanisms governing epigenetic functions in the context of ecologically relevant maternal effects. <em>Daphnia</em> make an ideal model for investigating molecular epigenetic mechanisms and ecological maternal effects because they will reproduce asexually in the lab. <em>Daphnia</em> are also known to have strong maternal effects, involving a variety of traits and environmental variables. Using two clones of <em>Daphnia</em> <em>pulex</em>, we investigated the plasticity of life history and DNA methyltransferase (Dnmt) gene expression with respect to food limitation within- and across-generations. We found strong evidence of genotypic variation of responses of life history and Dnmt expression to low food diets, both within- and across-generations. In general, effects of offspring diet were larger than either the direct maternal effect or offspring-maternal environment interactions, but the direction of the maternal effect was usually in the opposite direction of the within-generation effect. For both life history and Dnmt expression, we also found that when offspring had low food, effects of the maternal environment were stronger than when offspring had high food.</p>
FIG. 1 in Morphological description and molecular phylogeny of two diatom clones from the genus Ulnaria (Kützing) Compère isolated from an ultraoligotrophic lake at the Pole of Cold in the Northern Hemisphere, Republic of Sakha (Yakutia), Russia
FIG. 1. — Study site (62°33'33"N; 143°36'27"E), Lake Labynkyr, Sakha Republic (Yakutia), Russia.
Flow cytometry data (Clone triplets experiment)
<p>Flow cytometry data of publication:</p> <blockquote> <p>Stelzer, C.P., M. Pichler, P. Stadler, Genome streamlining and clonal erosion in nutrient-limited environments: a test using genome-size variable populations, <em>Evolution</em>, Volume 77, Issue 11, November 2023, Pages 2378–2391, <a href="https://doi.org/10.1093/evolut/qpad144">https://doi.org/10.1093/evolut/qpad144</a></p> </blockquote> <p>Please cite this study if you use the data.</p> <p> </p> <p>Experiments with three clones differing in genome size</p> <p>First Run (05.07.2017-09.08.2017)</p> <p>Second Run (17.08.2017-27.09.2017)</p>
Speech-to-speech Voice-cloning Care (SVCC) to Improve ICU-acquired Anxiety for Critically Ill Patients
ClinicalTrials.gov study NCT06743321. IPD Sharing: NO. Countries: 1. Publications: 11.
The maternal effects of dietary restriction on Dnmt expression and reproduction in two clones of Daphnia pulex
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Data from: Comprehensive cDNA cloning and putative feature analysis of endogenous cellulases possessed by the Pacific oyster, Crassostrea gigas
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Are competitive interactions between aphid clones mediated by facultative endosymbionts?
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Effects of benign and heat-stress conditions on parent clones and their selfed offspring of the pea aphid
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Gene expression data from clones of FAO cells with different glucose production capability
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Subgenome annotations for allotetraploid potato wild relative Solanum acaule, clone AA9
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16S rDNA sequencing data for characterizing the endosymbionts of leaf curl plum aphid ( Brachycaudus helichrysi) clones
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An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
<p>Therapeutic antibiotic use drives the spread of antibiotic resistance, a major threat to public health. Ideally, clinicians could treat infections with antibiotics without fueling transmission of resistant pathogens. Here, we show proof of concept for an adjunctive therapy approach that allows treatment of target pathogens without the emergence and onward transmission of resistance. Like many of the bacterial species responsible for the antimicrobial resistance crisis, vancomycin-resistant <i>Enterococcus</i> (VRE) is a colonizing opportunistic pathogen and an important cause of drug-resistant healthcare-associated infections. VRE causes life-threatening infections in the bloodstream, but spreads via fecal-oral transmission because it asymptomatically colonizes the gastrointestinal (GI) tract. Thus, there is a physical separation between the VRE targeted by treatment (those in the blood) and the VRE contributing to onward transmission (those in the GI tract). An oral adjuvant that could eliminate or inactivate antibiotic in the GI tract would make possible intravenous patient treatment without promoting transmissible resistance. We tested this idea in a mouse model of VRE GI tract colonization using cholestyramine, which we show binds daptomycin, one of the few remaining front-line antibiotics against VRE. Adjunctive cholestyramine therapy reduced the fecal shedding of daptomycin-resistant VRE by up to 80-fold in mice treated with daptomycin. These results provide proof-of-concept for an approach that could reduce the spread of antibiotic resistance for many important hospital pathogens.</p>
Unique mode of cell division by the mycobacterial genetic resister clones emerging de novo from the antibiotic surviving population
<p>Live cell and timelapse microscopic images of the cells taken from different time points post antibiotic (Rifampicin and Moxifloxacin) exposure. The cells post antibiotic exposure, during their regrowth, showed multiple constriction to divide and generate sister antibiotic resister daughter cells with abrupt increased cell number within less division time by multiple septation. The phenomena of multiple septation can be seen in Miscellaneous Figures (MF. 1-4) and Miscellaneous Movies (MF. 1-4). </p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.