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datasets available to search
ShareScore release 0.9.0
Dataset results
95 results for “diffuse intrinsic pontine glioma”
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
ClinicalTrials.gov study NCT03605550. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma
ClinicalTrials.gov study NCT04749641. IPD Sharing: NO. Countries: 1. Publications: 0.
A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma
ClinicalTrials.gov study NCT04978727. IPD Sharing: YES. Countries: 2. Publications: 0.
Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma
ClinicalTrials.gov study NCT01165333. IPD Sharing: NO. Countries: 1. Publications: 0.
Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma
ClinicalTrials.gov study NCT01952769. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG)
ClinicalTrials.gov study NCT05630209. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma
ClinicalTrials.gov study NCT02992015. IPD Sharing: NO. Countries: 1. Publications: 0.
Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
ClinicalTrials.gov study NCT02359565. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Generation of diffuse intrinsic pontine glioma mouse models by brainstem targeted in utero electroporation
GEO Series GSE128807. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Histone H3 K27M mediated Regulation of Cancer Cell Stemness and Differentiation in Diffuse Intrinsic Pontine Glioma (DIPG)
GEO Series GSE216961. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Oncohistone H3.3K27M-driven CREB5/ID1 Axis Mediates the Malignant Cell States of Diffuse Intrinsic Pontine Glioma (DIPG) [ATAC-seq]
GEO Series GSE250461. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
SUV39H1 inhibition by Chaetocin targets stemness and oncogenic networks and synergizes with ONC201 against Diffuse intrinsic pontine gliomas [CUT&RUN]
GEO Series GSE225028. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting SWI/SNF ATPases in H3.3K27M Diffuse Intrinsic Pontine Gliomas [ATAC-Seq]
GEO Series GSE229453. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
SUV39H1 inhibition by Chaetocin targets stemness and oncogenic networks and synergizes with ONC201 against Diffuse intrinsic pontine gliomas
GEO Series GSE225029. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide Analyses of Diffuse Intrinsic Pontine Gliomas
GEO Series GSE26576. Homo sapiens. 126 samples. Type: Expression profiling by array; Genome variation profiling by SNP array.
Oncohistone H3.3K27M-driven CREB5/ID1 Axis Mediates the Malignant Cell States of Diffuse Intrinsic Pontine Glioma (DIPG)
GEO Series GSE250467. Mus musculus; Homo sapiens. 52 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Affymetrix SNP 6.0 array data for Diffuse Intrinsic Pontine Glioma
GEO Series GSE50024. Homo sapiens. 72 samples. Type: SNP genotyping by SNP array; Genome variation profiling by SNP array.
Functionally-defined Therapeutic Targets in Diffuse Intrinsic Pontine Glioma
Diffuse Intrinsic Pontine Glioma (DIPG) is a universally fatal childhood cancer. Here, we performed a chemical screen in patient-derived DIPG cell cultures along with RNAseq expression analysis and integrated computational modeling to identify potentially effective therapeutic strategies. Panobinostat, among the more promising agents identified, demonstrated efficacy in pontine orthotopic xenograft models of both H3K27M and histone WT DIPG. These data suggest the potential utility of specific drug combinations and provides evidence of in vivo treatment efficacy of the multi-histone deacetylase inhibitor panobinostat.
Oncohistone H3.3K27M-driven CREB5/ID1 Axis Mediates the Malignant Cell States of Diffuse Intrinsic Pontine Glioma (DIPG) [CUT&Tag]
GEO Series GSE250464. Homo sapiens. 26 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
131I-omburtamab Delivered by Convection-Enhanced Delivery in Patients With Diffuse Intrinsic Pontine Glioma
ClinicalTrials.gov study NCT05063357. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.