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ShareScore release 0.9.0
Dataset results
71 results for “dimethyl fumarate”
Study to Explore the Onset of Efficacy on Magnetic Resonance Disease Activity of BG00012 (Dimethyl Fumarate) in Patients With Relapsing remitTing Multiple Sclerosis
ClinicalTrials.gov study NCT02472938. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Combination of the Immune Modulator Dimethyl Fumarate With Intraarterial Treatment in Acute Ischemic Stroke
ClinicalTrials.gov study NCT04891497. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Observational Study in Patients With Relapsing-Remitting Multiple Sclerosis Switched to Bafiertam® From Dimethyl Fumarate
ClinicalTrials.gov study NCT04925778. IPD Sharing: NO. Countries: 0. Publications: 0.
Study to Evaluate Fatigue in Participants With Relapsing Remitting Multiple Sclerosis When Treated With Dimethyl Fumarate
ClinicalTrials.gov study NCT02090348. IPD Sharing: Not stated. Countries: 0. Publications: 0.
A Phase IV Study of Dimethyl Fumarate Enteric-coated Capsules for Relapsing Multiple Sclerosis (RMS)
ClinicalTrials.gov study NCT07138833. IPD Sharing: Not stated. Countries: 0. Publications: 0.
A sensitization-free dimethyl fumarate (DMF) pro-drug, isosorbide di-(methyl fumarate) (IDMF), provides a topical treatment candidate for psoriasis
GEO Series GSE175474. Homo sapiens; Mus musculus. 8 samples. Type: Expression profiling by array; Expression profiling by high throughput sequencing.
Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2
GEO Series GSE269610. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
A sensitization-free dimethyl fumarate (DMF) pro-drug, isosorbide di-(methyl fumarate) (IDMF), provides a topical treatment candidate for psoriasis [RNA-seq]
GEO Series GSE175471. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Circulating microRNAs in relapsing MS patients treated with dimethyl fumarate in the phase 4 TREMEND trial
GEO Series GSE215450. Homo sapiens. 211 samples. Type: Non-coding RNA profiling by array.
A sensitization-free dimethyl fumarate (DMF) pro-drug, isosorbide di-(methyl fumarate) (IDMF), provides a topical treatment candidate for psoriasis [microarray]
GEO Series GSE175473. Homo sapiens. 4 samples. Type: Expression profiling by array.
Evidence for novel cell defense mechanisms sustained by dimethyl fumarate in multiple sclerosis patients: the HuR/SOD2 cascade
<p><strong>Introduction - T</strong>his database includes the raw data linked with the paper <em>Evidence for novel cell defense mechanisms sustained by dimethyl fumarate in multiple sclerosis patients: the HuR/SOD2 cascade.</em></p> <p>In this paper, we reported the HuR protein levels in peripheral blood mononuclear cells (PBMCs) from MS patients before and after dimethyl fumarate (DMF) treatment compared to healthy controls (HC). Considering that HuR may act on different targets playing a protective role against oxidative stress, we had the goal of disclosing whether MnSOD could represent a new molecular target of HuR and the potential influence of DMF treatment on this interaction .</p> <p><strong>Methods - </strong>PBMCs from 20 patients with MS and 20 matched HC were used to evaluate HuR, MnSOD and Nrf2 protein content by Western blot, before and after 12 months of DMF treatment.</p> <p>Immunoprecipitation experiments coupled with RNA extraction in PBMCs were performed to explore whether MnSOD mRNA could be physically bound by HuR and whether this binding could be affected by 12 months of DMF treatment.</p> <p><strong>Results </strong>- In PBMCs, HuR protein interacts with MnSOD transcript both in HC and in MS patients naïve to disease modifying treatment. This interaction is positively affected by 12 months of DMF treatment. PBMCs from MS patients have a lower HuR and MnSOD protein content compared to matched HC (HuR: p<0.01, MnSOD p<0.01). Of interest, 12 months of DMF treatment in MS patients restore the amount of both HuR protein and MnSOD enzyme to the levels observed in HC. We also confirmed that Nrf2 is an HuR target, and we report that its levels are significantly increased in MS patients naïve to disease modifying treatment and remain elevated following DMF administration.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.