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119
datasets available to search
ShareScore release 0.9.0
Dataset results
119 results for “disease susceptibility”
Singel cell RNA sequencing of an F1 cross of Marek’s disease resistant and susceptible chickens
GEO Series GSE278696. Gallus gallus. 6 samples. Type: Expression profiling by high throughput sequencing.
Comparative transcriptomics reveals the different gene expression pattern related to wilt disease resistance and susceptibility in biodiesel plants of Vernicia
GEO Series GSE80228. Vernicia montana; Vernicia fordii. 24 samples. Type: Expression profiling by high throughput sequencing.
Single-cell transcriptomics and in vitro lineage tracing reveals differential susceptibility of human iPSC-derived midbrain dopaminergic neurons in a cellular model of Parkinson’s disease
GEO Series GSE247600. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Next-generation interaction screening to discover Mla6aa1-161 related protein-protein interactions regulating barley powdery mildew disease immunity and susceptibility.
GEO Series GSE164814. Hordeum vulgare; Blumeria hordei. 6 samples. Type: Other.
Next-generation interaction screening to discover Mla6aa1-225 related protein-protein interactions regulating barley powdery mildew disease immunity and susceptibility.
GEO Series GSE164815. Hordeum vulgare; Blumeria hordei. 6 samples. Type: Other.
Data from: Common variants in CLDN2 and MORC4 genes confer disease susceptibility in patients with chronic pancreatitis
A recent genome-wide association study (GWAS) identified association with variants in X-linked CLDN2 and MORC4, and PRSS1-PRSS2 loci with chronic pancreatitis (CP) in North American patients of European ancestry. We selected 9 variants from the reported GWAS and replicated the association with CP in Indian patients by genotyping 1807 unrelated Indians of Indo-European ethnicity, including 519 patients with CP and 1288 controls. The etiology of CP was idiopathic in 83.62% and alcoholic in 16.38% of 519 patients. Our study confirmed a significant association of 2 variants in CLDN2 gene (rs4409525—OR 1.71, P = 1.38 x 10-09; rs12008279—OR 1.56, P = 1.53 x 10-04) and 2 variants in MORC4 gene (rs12688220—OR 1.72, P = 9.20 x 10-09; rs6622126—OR 1.75, P = 4.04x10-05) in Indian patients with CP. We also found significant association at PRSS1-PRSS2 locus (OR 0.60; P = 9.92 x 10-06) and SAMD12-TNFRSF11B (OR 0.49, 95% CI [0.31–0.78], P = 0.0027). A variant in the gene MORC4 (rs12688220) showed significant interaction with alcohol (OR for homozygous and heterozygous risk allele -14.62 and 1.51 respectively, P = 0.0068) suggesting gene-environment interaction. A combined analysis of the genes CLDN2 and MORC4 based on an effective risk allele score revealed a higher percentage of individuals homozygous for the risk allele in CP cases with 5.09 fold enhanced risk in individuals with 7 or more effective risk alleles compared with individuals with 3 or less risk alleles (P = 1.88 x 10-14). Genetic variants in CLDN2 and MORC4 genes were associated with CP in Indian patients.
Identifying Shared Genetic Susceptibility Regions in Chronic Beryllium Disease and Sarcoidosis
ClinicalTrials.gov study NCT00560989. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Familial Intrahepatic Cholestasis-related Genes Associated with Disease Susceptibility in Hepato-biliary Cancers
ClinicalTrials.gov study NCT06777914. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Genetic Variants and Susceptibility to Diseases of Prematurity in Very Low Birth-Weight Infants
ClinicalTrials.gov study NCT00710112. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers
ClinicalTrials.gov study NCT04722835. IPD Sharing: NO. Countries: 1. Publications: 0.
Genetic Susceptibility to Rheumatic Heart Disease in the Pacific Region
ClinicalTrials.gov study NCT02188862. IPD Sharing: Not stated. Countries: 3. Publications: 0.
Genome-wide Study for Disease Susceptibility Gene(s) in Patients With Hand Osteoarthritis
ClinicalTrials.gov study NCT01981265. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Toll-like Receptor 2 Gene Polymorphism, Serum Cytokines and Susceptibility to Disease Severity or Treatment Response of Pulmonary Tuberculosis
ClinicalTrials.gov study NCT00772408. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Correlation of Genetic Susceptibility Genes to Inflammatory Bowel Disease in Chinese Han Population
ClinicalTrials.gov study NCT05071742. IPD Sharing: NO. Countries: 1. Publications: 0.
Newborn Screening for Genetic Susceptibility to Type 1 Diabetes and Celiac Disease and Prospective Follow-up Study
ClinicalTrials.gov study NCT04958356. IPD Sharing: NO. Countries: 1. Publications: 0.
Parkinson's Diseases Susceptibility Genes and Pesticides
ClinicalTrials.gov study NCT00044590. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Susceptibility to Infectious Diseases in Obesity
ClinicalTrials.gov study NCT05975541. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Long-term Aspirin Therapy as a Predictor of Decreased Susceptibility to SARS-CoV-2 Infection in Aspirin-Exacerbated Respiratory Disease
ClinicalTrials.gov study NCT05797597. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Whole-transcriptome microarray to identify sexually dimorphic RNA transcripts that are differentially expressed in disease-susceptible versus nonsusceptible CNS regions of male and female SJL mice
GEO Series GSE55718. Mus musculus. 24 samples. Type: Expression profiling by array.
Toxicity of atrazine and nonylphenol in juvenile rainbow trout (Oncorhynchus mykiss): Effects on general health, disease susceptibility and gene expression
GEO Series GSE38726. Oncorhynchus mykiss; Salmo salar. 24 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.