Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
4,683
datasets available to search
ShareScore release 0.9.0
Dataset results
4,683 results for “embryonic”
(08)-Strobl2021A-DS0002 – Tribolium castaneum ACOS{ATub'H2B-mRuby} #1 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy
<p>(08)-Strobl2021A-DS0002 – <em>Tribolium castaneum</em> ACOS{ATub'H2B-mRuby} #1 subline long-term live imaging data of embryonic development acquired with light sheet fluorescence microscopy</p>
(08)-Strobl2021A-DS0001 – Tribolium castaneum AGOC{Zen1'#O(LA)-mEmerald} #1 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy
<p>(08)-Strobl2021A-DS0001 – <em>Tribolium castaneum</em> AGOC{Zen1'#O(LA)-mEmerald} #1 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy</p>
(07)-Ratke2020A-DS0005 – Tribolium castaneum AGOC{Zen1'#O(LA)-mEmerald} #2 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy
<p>(07)-Ratke2020A-DS0005 – <em>Tribolium castaneum</em> AGOC{Zen1'#O(LA)-mEmerald} #2 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy</p>
(07)-Ratke2020A-DS0004 – Tribolium castaneum AGOC{Zen1'#O(LA)-mEmerald} #1 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy
<p>(07)-Ratke2020A-DS0004 – <em>Tribolium castaneum</em> AGOC{Zen1'#O(LA)-mEmerald} #1 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy</p>
(07)-Ratke2020A-DS0003 – Drosophila melanogaster w[*]; P{w[+mC]=His2Av-EGFP.C}2/SM6a line long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy
<p>(07)-Ratke2020A-DS0003 – <em>Drosophila melanogaster</em> w[*]; P{w[+mC]=His2Av-EGFP.C}2/SM6a line long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy</p>
(07)-Ratke2020A-DS0001 – Drosophila melanogaster y[1] w[67c23]; P{w[+mC]=Ubi-GFP.nls}ID-2; P{Ubi-GFP.nls}ID-3 line long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy
<p>(07)-Ratke2020A-DS0001 – <em>Drosophila melanogaster</em> y[1] w[67c23]; P{w[+mC]=Ubi-GFP.nls}ID-2; P{Ubi-GFP.nls}ID-3 line long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy</p>
(08)-Strobl2021A-DS0003 – Tribolium castaneum Gruul #1 hybrid line long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy
<p>(08)-Strobl2021A-DS0003 – <em>Tribolium castaneum</em> Gruul #1 hybrid line long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy</p>
(07)-Ratke2020A-DS0006 – Tribolium castaneum AGOC{Zen1'#O(LA)-mEmerald} #3 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy
<p>(07)-Ratke2020A-DS0006 – <em>Tribolium castaneum</em> AGOC{Zen1'#O(LA)-mEmerald} #3 subline long-term live imaging dataset of embryonic development acquired with light sheet fluorescence microscopy</p>
Systematic Scoping Literature Review of Embryonic Stem Cells In Vitro Developmental Toxicity Tests: Included publications library
<p>The publications included in the systematic scoping review conducted according to the protocol:<a href="https://zenodo.org/record/2528920">https://zenodo.org/record/2528920</a></p> <p> </p>
Figure 1 in Embryo retention, character optimization, and the origin of the extra-embryonic membranes of the amniotic egg
Figure 1. Sarcopterygian phylogeny showing an optimization of embryo retention (character 1), as previously advocated by Laurin and Girondot (1999). The only modification is that all terminal taxa are in the present tree, instead of collapsing Monotremata and Theria into Mammalia, to better match the character distribution shown in Table I, and that Actinistia is coded as unknown (as shown by the absence of a data box below that taxon).
Figure 3 in Embryo retention, character optimization, and the origin of the extra-embryonic membranes of the amniotic egg
Figure 3. Sarcopterygian phylogeny showing an optimization of the developmental stage at oviposition (character 2, with ordered states). This optimization suggests that the ancestral amniote laid its eggs at the gastrula developmental stage (equivalent to absence of extended embryo retention). If the character is left unordered, the ancestral condition for amniotes is to lay eggs in the post-neurula embryonic stage (equivalent to presence of extended embryo retention).
FIG. 5 in New data on embryonic development of Halisarca dujardini Johnston, 1842 (Demospongiae, Halisarcida)
FIG. 5. — Scheme of H. dujardini embryonic development; A, mature egg; B, early cleavage; C, beginning of blastomere polarization; D, multipolar immigration; E, stage larval polarization; F, formation of internal sphere and migration of maternal eosinophilic granular amoebocytes into larva; G, disphaerula, larva of H. dujardini. Abbreviations: bi, blastocoel; ec, embryonic capsule; efa, eosinophilic amoebocytes; ic, internal cells; isp, internal sphere; mc, migrated cells; ppc, posterior pole cells; tc, transition cells; yg, yolk granules.
FIG. 4. — A in New data on embryonic development of Halisarca dujardini Johnston, 1842 (Demospongiae, Halisarcida)
FIG. 4. — A, internal flagellate cells of disphaerula; B, flagellated cell that migrated from internal sphere. Abbreviations: f, flagellum; isc, internal sphere cavity; n, nucleus; yg, yolk granules; ba, bacteria. Scale bars: A, 4 µm; B, 1 µm.
FIG. 3. — A in New data on embryonic development of Halisarca dujardini Johnston, 1842 (Demospongiae, Halisarcida)
FIG. 3. — A, division of external flagellate cells in prelarva; B, maternal eosinophilic granular amoebocyte between internal cells of disphaerula; C, posterior pole of larva; D, external flagellate epithelium of larva. Abbreviations: ba, bacteria; ic, internal cells; ec, embryonic capsule; ppc, posterior pole cells; tc, transition cells; dc, divided cell; ecc, embryonic capsule cell; f, flagellum; n, nucleus; yg, yolk granules. Scale bars: A, 5 µm; B, 5 µm; C, 10 µm; D, 5 µm.
FIG. 2. — A in New data on embryonic development of Halisarca dujardini Johnston, 1842 (Demospongiae, Halisarcida)
FIG. 2. — A, cleaving embryos in 8-cell stage; B, blastula after immigration of external cells; C, stage of invagination of flagellate cells forming internal sphere; D, disphaerula of H. dujardini. Abbreviations: ec, embryonic capsule; ic, internal cells; n, nucleus; efc, external flagellate cells; b, blastomere; bi, blastocoel; ifc, internal flagellate cells; is, internal sphere; ppc, posterior pole cells; tc, transition cells. Scale bars: A, 20 µm; B, 15 µm; C, 20 µm; D, 10 µm.
Example of determination of C. niloticus embryonic age through the egg band during an artificial incubation at 30.5°C
<p>Example of determination of C. niloticus embryonic age through the egg band during an artificial incubation at 30.5°C.</p> <p>(valid only for eggs incubated at a temperature around 30.5°C)</p>
Circuit mechanisms underlying embryonic retinal waves
<p>Spontaneous activity is a hallmark of developing neural systems. In the retina, spontaneous activity comes in the form of retinal waves, comprised of three stages persisting from embryonic day 16 (E16) to eye opening at postnatal day 14 (P14). Though postnatal retinal waves have been well characterized, little is known about the spatiotemporal properties or the mechanisms mediating embryonic retinal waves, designated Stage 1 waves. Using a custom-built macroscope to record spontaneous calcium transients from whole embryonic retinas, we show that Stage 1 waves are initiated at several locations across the retina and propagate across a broad range of areas. A gap junction antagonist, meclofenamic acid, reduced the frequency and size of Stage 1 waves, nearly abolishing them. The general nAChR antagonist, hexamethonium similarly nearly abolished Stage 1 waves. Application of the α4β2 nAChR antagonist dihydro-ß-erythroidine only slightly reduced the frequency of waves but significantly reduced the number of cells that participated in waves. Thus, Stage 1 waves are mediated by a complex circuitry involving subtypes of nAChRs and gap junctions. Stage 1 waves in mice lacking the β2 subunit of the nAChRs (β2-nAChR-KO) were reduced, but in contrast to WT mice, they persisted in the hexamethonium and were completely blocked by meclofenamic acid. To assay the impact of Stage 1 waves on retinal development, we compared the spatial distribution of a subtype of retinal ganglion cells, intrinsically photosensitive retinal ganglion cells (ipRGCs), which undergo a significant amount of cell death, in WT and β2-nAChR-KO mice. We found that the developmental decrease of ipRGC density is preserved between WT and β2-nAChR-KO mice, indicating that processes regulating ipRGC distribution are not influenced by spontaneous activity.</p>
Bulk RNA-seq dataset of human embryonic stem cells (hESCs) differentiation
<p>The dataset consists of 31 bulk samples obtained from human embryonic stem cells undergoing undirected differentiation. The samples were collected at 16 time points on days 0 and 7-21 of differentiation. The file contains the raw read counts.</p> <p>More details can be found in:</p> <p>SPIRAL: Significant Process InfeRence ALgorithm for single cell RNA-sequencing and spatial transcriptomics\<br> Hadas Biran, Tamar Hashimshony, Tamar Lahav, Or Efrat, Yael Mandel-Gutfreund, and Zohar Yakhini</p> <p> <a href="https://doi.org/10.1101/2022.05.24.493189">https://doi.org/10.1101/2022.05.24.493189</a></p>
Figure 3 in The study of exposure times and dose-escalation of tick saliva on mouse embryonic stem cell proliferation
Figure 3. Effect of D. marginatus SGE (0-160 µg/ml) on mouse embryonic stem cell proliferation and viability. Values represent relative fold change of cell viability normalized to untreated negative control. The Geisser–Greenhouse correction and Dunnett´s test on multiple comparison were used. All experiments have the P value <0.05, on three different time laps. The results are mean ± standard deviation (SD) from a representative experiment carried out in triplicate and were seeded in equal amount in 3 different 96-well cultured plates.
Figure 2 in The study of exposure times and dose-escalation of tick saliva on mouse embryonic stem cell proliferation
Figure 2. Effect of R. bursa SGE (0-160 µg/ml) on mouse embryonic stem cell proliferation and viability. Values represent relative fold change of cell viability normalized to untreated negative control. The Geisser–Greenhouse correction and Dunnett´s test on multiple comparison were used. The results are mean ± standard deviation (SD) from a representative experiment carried out in triplicate and were seeded in equal amount in 3 different 96-well cultured plates.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.