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ShareScore release 0.9.0
Dataset results
206 results for “functional MRI”
Measuring Distress Tolerance With Functional MRI
ClinicalTrials.gov study NCT01038232. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Functional MRI in the Nile crocodile: a new avenue for evolutionary neurobiology
Crocodilians are important for understanding the evolutionary history of amniote neural systems as they are the nearest extant relatives of modern birds and share a stem amniote ancestor with mammals. Although the crocodilian brain has been investigated anatomically, functional studies are rare. Here we employed fMRI, never tested in poikilotherms, to investigate crocodilian telencephalic sensory processing. Juvenile Crocodylus niloticus were placed in a 7T MRI scanner to record BOLD signal changes during presentation of visual as well as auditory stimuli. Visual stimulation increased BOLD signals in rostral to mid-caudal portions of the dorso-lateral anterior dorsal ventricular ridge (ADVR). Simple auditory stimuli led to signal increase in the rostromedial and caudocentral ADVR. These activation patterns are in line with previously described projection fields of diencephalic sensory fibers. Furthermore, complex auditory stimuli activated additional regions of the caudomedial ADVR. The recruitment of these additional, presumably higher-order, sensory areas reflect observations made in birds and mammals. Our results indicate that structural and functional aspects of sensory processing have been likely conserved during the evolution of sauropsids. In addition, our study shows that fMRI can be utilized to investigate neural processing in poikilotherms, providing a new avenue for neurobiological research in these critical species.
Dynamic pulmonary MRI using motion-state weighted motion-compensation (MostMoCo) reconstruction with ultrashort TE: A structural and functional study
<p>A volunteer lung UTE MRI dataset and SI navigators used in MostMoCo.</p>
Data from: Maximizing negative correlations in resting-state functional connectivity MRI by time-lag
This paper aims to better understand the physiological meaning of negative correlations in resting state functional connectivity MRI (r-fcMRI). The correlations between anatomy-based brain regions of 18 healthy humans were calculated and analyzed with and without a correction for global signal and with and without spatial smoothing. In addition, correlations between anatomy-based brain regions of 18 naïve anesthetized rats were calculated and compared to the human data. T-statistics were used to differentiate between positive and negative connections. The application of spatial smoothing and global signal correction increased the number of significant positive connections but their effect on negative connections was complex. Positive connections were mainly observed between cortical structures while most negative connections were observed between cortical and non-cortical structures with almost no negative connections between non-cortical structures. In both human and rats, negative connections were never observed between bilateral homologous regions. The main difference between positive and negative connections in both the human and rat data was that positive connections became less significant with time-lags, while negative connections became more significant with time-lag. This effect was evident in all four types of analyses (with and without global signal correction and spatial smoothing) but was most significant in the analysis with no correction for the global signal. We hypothesize that the valence of r-fcMRI connectivity reflects the relative contributions of cerebral blood volume (CBV) and flow (CBF) to the BOLD signal and that these relative contributions are location-specific. If cerebral circulation is primarily regulated by CBF in one region and by CBV in another, a functional connection between these regions can manifest as an r-fcMRI negative and time-delayed correlation. Similarly, negative correlations could result from spatially inhomogeneous responses of rCBV or rCBF alone. Consequently, neuronal regulation of brain circulation may be deduced from the valence of r-fcMRI connectivity.
Functional Applications of Hyperpolarized 129Xe MRI
ClinicalTrials.gov study NCT01697332. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Hyperpolarized Xenon MRI for Assessment of Pulmonary Function in Lung Resection
ClinicalTrials.gov study NCT03417687. IPD Sharing: NO. Countries: 1. Publications: 0.
A Functional MRI Study on Erenumab Treatment Effects in Episodic Migraine Patients
ClinicalTrials.gov study NCT03977649. IPD Sharing: YES. Countries: 1. Publications: 0.
Functional MRI Before and After Treatment for Depression
ClinicalTrials.gov study NCT00896441. IPD Sharing: NO. Countries: 1. Publications: 0.
Cardiac Function and Metabolism in Young Adults Born Premature (PET-MRI)
ClinicalTrials.gov study NCT03245723. IPD Sharing: NO. Countries: 1. Publications: 0.
Assessment of Renal Function by Multiparametric MRI
ClinicalTrials.gov study NCT06407375. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Dynamic Magnetic Resonance Imaging (MRI) for Lung Tumor Motion and Lung Function (GCC 0943)
ClinicalTrials.gov study NCT01016938. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Brain Activities Associated With Different Facial Expressions Using Blood Oxygenation Level Dependent Functional MRI
ClinicalTrials.gov study NCT00096564. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Study on Neuroepithelial Tumor Grading and Pseudoprogression After Glioma Therapy Using Advanced Functional MRI Techniques
ClinicalTrials.gov study NCT02622620. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Neural Changes of Exercise: a Functional MRI Study
ClinicalTrials.gov study NCT02541136. IPD Sharing: Not stated. Countries: 0. Publications: 7.
MRI Study of Musculoskeletal Function
ClinicalTrials.gov study NCT00051857. IPD Sharing: YES. Countries: 1. Publications: 0.
Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide
ClinicalTrials.gov study NCT03566511. IPD Sharing: NO. Countries: 1. Publications: 0.
Functional MRI Use in Prostate Radiation Treatment Planning
ClinicalTrials.gov study NCT01985932. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Functional MRI in the Nile crocodile: a new avenue for evolutionary neurobiology
Open the record for dataset details and reuse information.
Data from: Maximizing negative correlations in resting-state functional connectivity MRI by time-lag
Open the record for dataset details and reuse information.
Data from: Intracranial atherosclerosis on 7T MRI and cognitive functioning – the SMART-MR study
<p><strong>Objective:</strong> To investigate the association between intracranial atherosclerosis (ICAS) and cognitive functioning in patients with a history of vascular disease.</p> <p><strong>Methods:</strong> Within the SMART-MR study cross-sectional analyses were performed in 130 patients (mean±SD age 68±9 years) with 7T vessel wall–magnetic resonance imaging data. Vessel wall lesions were rated according to established criteria and summed into a circulatory and artery-specific ICAS burden. Associations between ICAS burden and Z-scores of memory, executive functioning, working memory and processing speed, were estimated using linear regression analyses adjusted for age, sex, education, reading ability, and vascular risk factors.</p> <p><strong>Results:</strong> A total of 125 patients (96%) had ≥1 vessel wall lesions; the mean ICAS burden was 8.5±5.7.</p> <p>A statistically non-significant association was found between total ICAS burden and memory (b = -0.03 per +1 lesion; 95% CI -0.05 to 0.00). No associations were found for the other domains.</p> <p>A statistically significant association was found for ICAS burden of the posterior cerebral artery (PCA) and memory (b= -0.12 per +1 lesion; 95%CI -0.23 to -0.01) and executive functioning (b= -0.10 per +1 lesion; 95%CI -0.19 to -0.01). Statistically non-significant associations were found for the anterior cerebral artery (ACA) burden and memory (b= -0.13 per +1 lesion; 95%CI -0.26 to 0.01) and executive functioning (b= -0.11 per +1 lesion; 95%CI -0.22 to 0.01).</p> <p>Additional adjustments for large infarcts, white matter hyperintensities, lacunes and ≥50% carotid stenosis, produced similar results.</p> <p><strong>Conclusions:</strong> Our results suggest an artery-specific vulnerability of memory and executive functioning to ICAS, possibly due to strategic brain regions involved with these cognitive domains, which are located in the arterial territory of the PCA and ACA.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.