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Dataset results
109 results for “high-throughput screening”
A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening
<h1>Pan-Canadian Chemical Library</h1> <p>This Zenodo repository contains the cheap and druglike subset of the Pan-Canadian Chemical Library (PCCL) project. For more information, visit <a href="https://pccl.thesgc.org/" rel="nofollow">https://pccl.thesgc.org</a>.</p> <h2>PCCL library</h2> <p>The PCCL library is splitted by reaction, then by number of heavy atoms. Two types of files are available in zip archives:</p> <ul> <li>The SMILES format files, with the SMILES string and their product name,</li> <li>The CSV format file, with all the information generated during their enumeration: reagents, druglike properties, etc.</li> </ul> <p>Note: Purchasability is defined according to two integers: 1 for products only composed of BB-50 reagents, and 2 for products composed of BB-40 or BB-50 reagents. Read more about the meaning of these reagents groups in the article below.</p> <h2><a href="https://github.com/cbedart/PCCL#citation"></a>Citation</h2> <p>If you find the PCCL useful or if you use it, please cite our paper:</p> <p>Bedart, C. <em>et al.</em> A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening. ChemRxiv (2023).<br>doi:10.26434/chemrxiv-2023-jgbgv<br>This content is a preprint and has not been peer-reviewed.</p>
Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling
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Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening
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Signature analysis of high-throughput transcriptomics screening data for mechanistic inference and chemical grouping
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High-throughput screening for cell binding and repulsion peptides on multifunctionalized surfaces
<p><a name="_GoBack"></a>Tables with fluorescent intensity values after cell incubation for each peptide from libraries synthesized on peptide chips. Excel file “Supplementary Data 1.xlsx” represents the numerical source data for graphs Fig 2, Fig3, suppl Fig 1, suppl Fig 2. Excel file “Supplementary Data 2.xlsx” represents the numerical source data for suppl Fig. 3.</p>
Multi-site HPV Screening by High-throughput Sequencing in Patients With Chronic HPV-HR Infection Followed by Gynecology
ClinicalTrials.gov study NCT04901351. IPD Sharing: NO. Countries: 1. Publications: 0.
Cancer Stem Cell High-Throughput Drug Screening Study
ClinicalTrials.gov study NCT02654964. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma
ClinicalTrials.gov study NCT05380349. IPD Sharing: NO. Countries: 1. Publications: 0.
3D collagen high-throughput screen identifies drugs that induce epithelial polarity and enhance chemotherapy response in colorectal cancer
GEO Series GSE304081. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Data from: High-throughput screening for ligands of the HEPN domain of sacsin
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A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling
GEO Series GSE140745. Homo sapiens. 21 samples. Type: Other.
High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility
GEO Series GSE61735. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CASCADE - Customizable high-throughput platform for profiling cofactor recruitment to DNA to characterize cis-regulatory elements and screen non-coding SNPs
GEO Series GSE148945. Homo sapiens. 38 samples. Type: Other.
A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X-chromosome reactivation
GEO Series GSE85103. Mus musculus musculus x Mus musculus castaneus. 8 samples. Type: Expression profiling by high throughput sequencing.
Molecular indicators of hepatocellular carcinoma resistance to Y-90 microspheres revealed through high-throughput screening of cell lines and transcriptomics
GEO Series GSE312144. Homo sapiens. 51 samples. Type: Expression profiling by high throughput sequencing.
Demonstrating the utility of the ex vivo murine mycobacterial growth inhibition assay (MGIA) for high-throughput screening of tuberculosis vaccine candidates against multiple Mycobacterium tuberculosi
GEO Series GSE224469. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Signature Analysis of High-Throughput Transcriptomics Screening Data for Mechanistic Inference and Chemical Grouping
GEO Series GSE272548. . 0 samples. Type: Expression profiling by high throughput sequencing.
Screening of differentially expressed genes and microRNAs in rabbits with traumatic proliferative vitreoretinopathy based on high-throughput sequencing
GEO Series GSE285957. Oryctolagus cuniculus. 6 samples. Type: Expression profiling by high throughput sequencing.
A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2’-dC upon inhibition of ribonucleotide reductase-wide
GEO Series GSE72295. Mus musculus; Homo sapiens. 28 samples. Type: Methylation profiling by high throughput sequencing.
RNA sequencing of murine C2C12 cell treated with high-throughput screening hit compound 6,8-dimethyl-3-(4-phenyl-1H-imidazol-5-yl)quinolin-2(1H)-one.
GEO Series GSE125052. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.