Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
92
datasets available to search
ShareScore release 0.9.0
Dataset results
92 results for “host pathogen interaction”
Understanding Host-pathogen Interaction in the Respiratory Mucosa During Pregnancy
ClinicalTrials.gov study NCT04962477. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Phenotypic interactions between tree hosts and invasive forest pathogens in the light of globalization and climate change
Open the record for dataset details and reuse information.
Data from: Defining host–pathogen interactions employing an artificial intelligence workflow
Open the record for dataset details and reuse information.
Data from: The impact of bottlenecks on microbial survival, adaptation and phenotypic switching in host-pathogen interactions
Open the record for dataset details and reuse information.
Malaria Host Pathogen Interaction Center Experiment 04: Host and parasite gene transcript abundances, from bone marrow aspirate, of Macaca mulatta infected Plasmodium cynomolgi treated with artemether
GEO Series GSE94273. Macaca mulatta; Plasmodium cynomolgi strain B. 31 samples. Type: Expression profiling by high throughput sequencing.
The Staphylococcus aureus CamS lipoprotein is a repressor of toxin production that shapes host-pathogen interaction
GEO Series GSE239718. Staphylococcus aureus. 12 samples. Type: Expression profiling by high throughput sequencing.
Host and pathogen interaction: time course [zebrafish]
GEO Series GSE32118. Danio rerio. 27 samples. Type: Expression profiling by array.
Virome Data Explorer: A web resource to longitudinally explore respiratory viral infections, their interactions with other pathogens and host transcriptomic changes in over 100 people
GEO Series GSE223679. Homo sapiens. 847 samples. Type: Expression profiling by high throughput sequencing.
Combined transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions
GEO Series GSE83682. Mus musculus; Candida albicans. 80 samples. Type: Expression profiling by array.
An Integrated Approach to Understanding Host-Pathogen Interactions
GEO Series GSE94274. Macaca mulatta; Plasmodium coatneyi; Plasmodium cynomolgi strain B; Plasmodium cynomolgi ceylonensis; Macaca fascicularis; Plasmodium knowlesi. 556 samples. Type: Expression profiling by high throughput sequencing.
New insight into a host-pathogen interaction unveiled by transcriptomics response of the global insect pest Plutella xylostella to a fungal pathogen
GEO Series GSE72383. Plutella xylostella. 6 samples. Type: Expression profiling by high throughput sequencing.
Genomic Approaches to Dissect Human Host-pathogen Interactions in the Amazonian Rainforest
ClinicalTrials.gov study NCT05981378. IPD Sharing: NO. Countries: 0. Publications: 0.
Combined transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions [C. albicans]
GEO Series GSE83679. Candida albicans. 17 samples. Type: Expression profiling by array.
Host-pathogen interactions between Xanthomonas fragariae and its host Fragaria × ananassa investigated with a dual RNA-seq analysis
GEO Series GSE150636. Fragaria x ananassa. 6 samples. Type: Expression profiling by high throughput sequencing.
Spaceflight Analogue Culture Enhances the Host-Pathogen Interaction Between Salmonella and a 3-D Biomimetic Intestinal Co-Culture Model
Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian cells that can impact infection. However, our mechanistic understanding of how these environments regulate host-pathogen interactions in humans is poorly understood. Using a spaceflight analogue low fluid shear culture system, we investigated the effect of Low Shear Modeled Microgravity (LSMMG) culture on the colonization of Salmonella Typhimurium in a 3-D biomimetic model of human colonic epithelium containing macrophages. RNA-seq profiling of stationary phase wild type and delta hfq mutant bacteria alone indicated that LSMMG culture induced global changes in gene expression in both strains and that the RNA-binding protein Hfq played a significant role in regulating the transcriptional response of the pathogen to LSMMG culture. However, a core set of genes important for adhesion, invasion, and motility were commonly induced in both strains. LSMMG culture enhanced the colonization (adherence, invasion and intracellular survival) of Salmonella in this advanced model of intestinal epithelium using a mechanism that was independent of Hfq. Although S. Typhimurium delta hfq mutants are normally defective for invasion when grown as conventional shaking cultures, LSMMG conditions unexpectedly enabled high levels of colonization by an isogenic hfq mutant. In response to infection with either the wild type or mutant, host cells upregulated transcripts involved in inflammation, tissue remodeling, and wound healing during intracellular survival. Interestingly, infection by the hfq mutant led to fewer transcriptional differences between LSMMG- and control-infected host cells relative to infection with the wild type strain. This is the first study to investigate the effect of LSMMG culture on the interaction between S. Typhimurium and a 3-D model of human intestinal tissue. These findings advance our understanding of how physical forces can impact the early stages of human enteric salmonellosis.
Malaria Host Pathogen Interaction Center Experiment 04R: Host and parasite gene transcript abundances, from whole blood, of Macaca mulatta infected Plasmodium cynomolgi treated with artemether over 7
GEO Series GSE103507. Plasmodium cynomolgi strain B; Macaca mulatta. 33 samples. Type: Expression profiling by high throughput sequencing.
Malaria Host Pathogen Interaction Center Experiment 24: Host and parasite gene transcript abundances, from whole blood, of Macaca mulatta infected Plasmodium cynomolgi B strain treated with artemether
GEO Series GSE104101. Macaca mulatta; Plasmodium cynomolgi strain B. 15 samples. Type: Expression profiling by high throughput sequencing.
Malaria Host Pathogen Interaction Center Experiment 30: Pilot experiment for Macaca mulatta infected with Plasmodium knowlesi Malayan strain sporozoites to produce and integrate measures of acute prim
GEO Series GSE123495. Plasmodium knowlesi; Macaca mulatta. 63 samples. Type: Expression profiling by high throughput sequencing.
Host pathogen interaction between Staphylococcus aureus ATCC25923 and murine RAW264.7 macrophage-like cells
GEO Series GSE23538. Staphylococcus aureus; Mus musculus. 8 samples. Type: Expression profiling by array.
Accessible Homeostatic Gastric Organoids Reveal Secondary Cell Type-Specific Host-Pathogen Interactions in Helicobacter Pylori Infections
GEO Series GSE255276. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.