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1,740 results for “long-term study”
Vonoprazan Study in Patients With Erosive Esophagitis to Evaluate Long-term Safety
ClinicalTrials.gov study NCT02679508. IPD Sharing: YES. Countries: 1. Publications: 1.
An Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of LOU064 in Subjects With CSU
ClinicalTrials.gov study NCT04109313. IPD Sharing: YES. Countries: 15. Publications: 1.
A Safety Extension Study to Evaluate the Long-term Safety of QGE031 in Chronic Spontaneous Urticaria (CSU) Patients
ClinicalTrials.gov study NCT02649218. IPD Sharing: UNDECIDED. Countries: 10. Publications: 2.
Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogepant for the Prevention of Migraine in Participants With Episodic Migraine
ClinicalTrials.gov study NCT03939312. IPD Sharing: YES. Countries: 1. Publications: 4.
Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis
ClinicalTrials.gov study NCT03668613. IPD Sharing: YES. Countries: 9. Publications: 4.
Long-term Safety and Efficacy Study of DX-2930 (SHP643) to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAE
ClinicalTrials.gov study NCT02741596. IPD Sharing: YES. Countries: 7. Publications: 5.
Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study
ClinicalTrials.gov study NCT04084314. IPD Sharing: YES. Countries: 1. Publications: 1.
Long-term Extension Study of Ligelizumab in Food Allergy
ClinicalTrials.gov study NCT05678959. IPD Sharing: YES. Countries: 9. Publications: 1.
Data from: Demographic, behavioral, and ecological data from a long-term field study of wild baboons in Amboseli, Kenya
Open the record for dataset details and reuse information.
Long-term studies of secondary succession and community assembly in the prairie-forest ecotone of eastern Kansas, Old-field succession experiment
Local and regional-scale processes interact to govern the assembly, diversity and functioning of ecological communities. Evaluating the interplay of these differently-scaled processes in the regulation of ecological systems is a challenging problem, but is crucial towards understanding and predicting the potential effects of accelerated human activity on biological diversity and ecosystem sustainability. Since 2000, two long-term field experiments have been underway in grasslands of eastern Kansas to investigate the interplay of soil resource availability, species interactions and regional processes governing plant secondary succession, community assembly, biodiversity, and ecosystem functioning. Both experiments involve manipulations of soil nutrients in permanent grassland study plots and employ multi-species seed addition treatments to evaluate the contribution of dispersal limitation and regional constraints on local species pools to the regulation of plant community dynamics. Old-field succession experiment, previously funded by the National Science Foundation, was initiated in 2001 in a section of the abandoned hay field that was sprayed with herbicide, plowed and disked prior to the start of the study to investigate plant community dynamics in the context of old-field succession initiated on bare soil. The experimental design involves factorial experimental gradients of nitrogen (N) supply (four levels of N fertilization), phosphorus (P) supply (two levels of P fertilization) and plant propagule input achieved by adding seeds of 50+ native and naturalized species to half of the study plots. With annual sampling this experiment allows us to examine old-field succession and community assembly unfolding along gradients of N and P fertilization and under conditions of ambient and experimentally-enriched species pools.
Long-term study of tree cholla demography in the Los Pinos mountains, Sevilleta National Wildlife Refuge
This study was initiated in 2004 by TEX Miller to quantify individual-level demographic rates of tree cholla cacti (Cylindriopuntia imbricata) at the Sevilleta National Wildlife Refuge, Socorro Co., NM. This data package spans 2004-2018, though the study is maintained through the present. In each year, censuses were conducted over several days in the last week of May and/or the first week of June. Individuals were marked with aluminum tags and tracked longitudinally through time, with annual measures of survival, size, reproductive output, and interactions with insect herbivores and mutualists (extra-floral nectar-feeding ants). For the years 2004-2008, plants were grouped into spatial blocks (T1, T2, T3) lacking defined boundaries. Beginning in 2009, the study design changed to 30m x 30m plots (Plots 1-8) with an entirely new cohort of individuals that does not overlap with the 2004-2008 data. From 2009 onward, plots were searched each year and new plants were added to the census as they were discovered. Seedlings typically require several years of growth before they are detectable in our census, so counts of new plants in a given year do not necessarily reflect recruitment in that year. The data frame is set up such that one row is a transition year (May of year t to May of year t+1) for one individual; this means that all but the first and last years’ observations occur twice, once as the start of a transition year and once as the end.
SGS-LTER Long-Term Montioring Project: Arthropod Pitfall Trapping on Small Mammal Trapping Webs on the Central Plains Experimental Range, Nunn, Colorado, USA 1998-2006, ARS Study Number 118
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. Additional information and referenced materials can be found: http://hdl.handle.net/10217/83450. With the exception of heteromyids, eg kangaroo rats and pocket mice, most small rodents in shortgrass steppe are omnivorous. Depending on season, arthropods (insects and arachnids) make up 40-85% of the diet of grasshopper mice and thirteen-lined ground squirrels, the most widespread rodents in northern shortgrass steppe. Small mammals are among the most important predators of ground-dwelling macroarthropods and herbivorous insects provide a direct resource link between weather and plant production. Understanding temporal variability in the abundance of arthropods is central to determining the mechanisms that drive small rodent populations. At present, there are no long-term studies of arthropods in shortgrass steppe, despite the important role that these taxa play in grassland food webs. Beginning in 1998, we implemented field protocols to track changes in relative abundance of terrestrial macroarthropods in grassland and shrub-dominated habitats of shortgrass steppe. Sampling was conducted on the six trapping webs (three upland prairie, three lowland saltbush) where we studied rodent populations, and was conducted approximately monthly from May-September (4-5 sessions/ye
SGS-LTER Long-term Monitoring Project: Carnivore Scat Count on the Central Plains Experimental Range, Nunn, Colorado, USA 1997 -2006, , ARS Study Number 98
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. Additional information and referenced materials can be found: http://hdl.handle.net/10217/83392 Carnivores are among the most conspicuous, charismatic and economically important mammals in shortgrass steppe, yet relatively is little is known about their populations or of the ecological factors that determine their distribution and abundance, in part because densities tend to be low. Mammalian carnivores represent the top predators in grassland food webs, consuming rodents, rabbits, young ungulates and other small vertebrates. In addition, shortgrass steppe is the primary habitat of the swift fox (Vulpes velox), a species of special conservation concern throughout most of its range. Fox populations are thought to be limited by predation from coyotes (Canis latrans), the most common carnivore in these grasslands and a species of interest, both for its ecological roles and well as a target species for human exploitation, ie hunting and predator control. In 1994, we implemented a low-intensity sampling scheme to monitor long-term changes in relative abundance of mammalian carnivores and help us examine interactions between these predators and their small mammal prey, including rodents and rabbits. We estimated relative abundance of carnivores using scat surveys along a fi
SGS-LTER Long-term Monitoring Project: Spotlight Rabbit Count on the Central Plains Experimental Range, Nunn, Colorado, USA 1994-2006, ARS Study Number 98
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. Additional information and referenced materials can be found: http://hdl.handle.net/10217/83448. Rabbits are the most important small-mammal herbivores in shortgrass steppe, and may significant influence the physiognomy and population dynamics of herbaceous plants and woody shrubs. Rabbits also are the most important prey of mammalian carnivores such as coyotes and large raptors such as golden eagles and great horned owls. Two hares (Lepus californicus, L. townsendii) and one cottontail rabbit (Sylvilagus audubonii) occur in shortgrass steppe. In 1994, we initiated long-term studies to track changes in relative abundance of rabbits on the Central Plains Experimental Range (CPER). On four nights each year (one night each season, usually on new moon nights in January, April, July, October), we drove a 32-km route consisting of pasture two-track and gravel roads on the CPER. This was the same route as that driven for carnivore scat counts. Surveys began at twilight. Observers with two spotlights sat in the back of a 4WD pick-up driven at <15 mph. We recorded the perpendicular distance (in m) to each rabbit using a meter tape or range finder; the direction of the rabbit relative to the road; and noted if individuals were solitary or in clusters. We also recorded any carni
SGS-LTER Long-Term Monitoring Project: Small Mammals on Trapping Webs on the Central Plains Experimental Range, Nunn, Colorado, USA 1994 -2006, ARS Study Number 118
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. Additional information and referenced materials can be found: http://hdl.handle.net/10217/83452. Small mammals (rabbits, rodents) are integral components of semiarid ecosystems because of their roles as consumers of plants, seeds and arthropods, as soil disturbance agents, and as food for raptors, snakes and mammalian carnivores. Because of their vagility and intermediate trophic position, populations of small mammals may track changes in vegetation and the abiotic environment that may result from shifts in land-use and other anthropogenic disturbances. However, these populations are variable over space and time, and their response to environmental changes may not be immediately apparent given their behavioral flexibility and relatively long life-spans and generation times. Patterns in the distribution and abundance of small mammals thus may simultaneously reflect and affect the stability of the shortgrass-steppe ecosystem. Long-term studies of population and community dynamics therefore are needed to fully understand the role of small mammals in grassland ecosystems. In 1994, we implemented a sampling scheme to monitor long-term changes in relative abundance of small mammals in representative habitats of shortgrass steppe. We live-trapped nocturnal rodents twice each
SGS-LTER Long-Term Monitoring Project: Spermophilus tridecemlineatus on Small Mammal Trapping Webs on the Central Plains Experimental Range, Nunn, Colorado, USA 1999 -2006, ARS Study Number 118
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. Additional information and referenced materials can be found: http://hdl.handle.net/10217/83456. Small mammals (rabbits, rodents) are integral components of semiarid ecosystems because of their roles as consumers of plants, seeds and arthropods, as soil disturbance agents, and as food for raptors, snakes and mammalian carnivores. Because of their vagility and intermediate trophic position, populations of small mammals may track changes in vegetation and the abiotic environment that may result from shifts in land-use and other anthropogenic disturbances. However, these populations are variable over space and time, and their response to environmental changes may not be immediately apparent given their behavioral flexibility and relatively long life-spans and generation times. Patterns in the distribution and abundance of small mammals thus may simultaneously reflect and affect the stability of the shortgrass-steppe ecosystem. Long-term studies of population and community dynamics therefore are needed to fully understand the role of small mammals in grassland ecosystems. Thirteen-lined ground squirrels (Spermophilus tridecemlineatus, SPTR) are the most widely distributed rodent species in shortgrass steppe and the most important in terms of abundance and biomass. Like mo
SGS-LTER Long-Term Monitoring Project: Vegetation Cover on Small Mammal Trapping Webs on the Central Plains Experimental Range, Nunn, Colorado, USA 1999 -2006, ARS Study Number 118
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. Additional information and referenced materials can be found: http://hdl.handle.net/10217/83458. The abundance and diversity of small mammals in shortgrass steppe is strongly influenced by the structure and composition of vegetation. Vegetation structure provides cover from predators and harsh abiotic conditions. Plant species composition affects the types of seeds and herbaceous material available to granivores and herbivores, and influences arthropod populations, which are important prey for the omnivorous species that dominate in shortgrass steppe. Both vegetation structure and plant community composition are sensitive to the availability of precipitation as well as the activity of large mammalian herbivores. In 1999, we began measuring vegetation structure and plant community composition on the three grassland and three shrubland trapping webs where we live-trap small mammals. Vegetation measurements are made once each year, usually in mid-July. Percent canopy cover of each plant species was estimated visually in 30 0.10-m2 Daubenmire quadrats on each web. To estimate habitat structure, we measured the height of grass, forb and shrub plants adjacent to each quadrat, the density of half-shrubs, small mammal mounds and burrows, harvester ant mounds and the dimension
SGS-LTER Long-Term Monitoring Project: Vegetation Structure on Small Mammal Trapping Webs on the Central Plains Experimental Range, Nunn, Colorado, USA 1999 -2006, ARS Study Number 118
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. Additional information and referenced materials can be found: http://hdl.handle.net/10217/83458. The abundance and diversity of small mammals in shortgrass steppe is strongly influenced by the structure and composition of vegetation. Vegetation structure provides cover from predators and harsh abiotic conditions. Plant species composition affects the types of seeds and herbaceous material available to granivores and herbivores, and influences arthropod populations, which are important prey for the omnivorous species that dominate in shortgrass steppe. Both vegetation structure and plant community composition are sensitive to the availability of precipitation as well as the activity of large mammalian herbivores. In 1999, we began measuring vegetation structure and plant community composition on the three grassland and three shrubland trapping webs where we live-trap small mammals. Vegetation measurements are made once each year, usually in mid-July. Percent canopy cover of each plant species was estimated visually in 30 0.10-m2 Daubenmire quadrats on each web. To estimate habitat structure, we measured the height of grass, forb and shrub plants adjacent to each quadrat, the density of half-shrubs, small mammal mounds and burrows, harvester ant mounds and the dimension
SGS-LTER Long-term Seasonal Root Biomass on the Central Plains Experimental Range, Nunn, Colorado, USA 1985-2007, ARS Study Number 3
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. The belowground system in arid and semiarid regions can be of relatively greater importance than in more mesic systems because plant competition is most often for soil water rather than for light in aboveground canopies. Belowground plant biomass in the shortgrass steppe represents approximately 80% of the total. These data, entitled Long-Term Seasonal Root Biomass, were obtained in section 21 of the Central Plains Experimental Range from 1985-2008 in conjunction with a 14C labeling experiment designed to test isotope methods of estimating root production. Paired plots for each of eight replicate 14C labeled plots were established and cored on average six times per year over 13 years (five cores each plot each date as above). There were two primary objectives for collecting these data, 1) to compare estimates of root production (or belowground net primary production - BNPP) obtained using the sequential coring of biomass methods with various isotope, minirhizotron, ingrowth, and other methods, and 2) to examine long-term controls on the temporal dynamics of root biomass. This shortgrass steppe LTER site is the only place we are aware of that has compared most methods of estimating BNPP, including sequential coring, ingrowth cores, and ingrowth donuts, 14C pulse-isotop
SGS-LTER Ecosystem Stress Area - long-term density dataset following nutrient enrichment stress on the Central Plains Experimental Range in Nunn, Colorado, USA 1975-2011, ARS Study Number 3
This data package was produced by researchers working on the Shortgrass Steppe Long Term Ecological Research (SGS-LTER) Project, administered at Colorado State University. Long-term datasets and background information (proposals, reports, photographs, etc.) on the SGS-LTER project are contained in a comprehensive project collection within the Digital Collections of Colorado (http://digitool.library.colostate.edu/R/?func=collections&collection_id=3429). The data table and associated metadata document, which is generated in Ecological Metadata Language, may be available through other repositories serving the ecological research community and represent components of the larger SGS-LTER project collection. Water, nitrogen, and water-plus-nitrogen at levels beyond the range normally experience by shortgrass steppe communities were applied from 1971 through 1975, plant densities were sampled through 1977, and then sampling resumed in 1982, with sampling frequencies changing from annually to every other year. The initial sampling from 1970 to 1974 showed that the water and water plus nitrogen treatments had the strongest effect on plant community structure, both treatments increased biomass, and exotic weed species were noted on the water plus nitrogen treatment. Later sampling from 1982 to 1991 showed a ten-fold increase in exotic weed species on the water plus nitrogen plots as compared to the controls (Milchunas and Lauenroth 1995), a community change that has persisted on this site due to a chronic elevation of soil nitrogen caused by a plant tissue/soil organic matter feedback mechanism (Vinton and Burke 1995). In 1998, Six new treatments were superimposed on the historic study site. The six new treatments were: control, sugar, lignin, sawdust, lignin and sugar, and sawdust and sugar.In 2010, plots will be sampled every 5 years. Our objective in this study is to examine how plant communities change through time and explore implications of these changes for monitoring
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.