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826 results for “low level”
Pilot Study of Adding Raltegravir (MK-0518) to Antiretroviral Therapy in Patients With Low Level Viremia
ClinicalTrials.gov study NCT00618371. IPD Sharing: NO. Countries: 1. Publications: 7.
A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1)
ClinicalTrials.gov study NCT01333436. IPD Sharing: NO. Countries: 1. Publications: 1.
Low levels of genetic differentiation with isolation by geography and environment in populations of Drosophila melanogaster from across China
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Low levels of hybridization between domestic and wild Mallards wintering in the Lower Mississippi Flyway
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Genetic assessment reveals inbreeding, possible hybridization, and low levels of genetic structure in a declining goose population
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Low circulating levels of miR-451a in girls with Polycystic Ovary Syndrome: different effects of randomized treatments
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Data from: Low levels of hypertension screening in HIV care clinics in rural Uganda: a mixed methods study
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Low oxygen levels can help to prevent the detrimental effect of acute warming on mitochondrial efficiency in fish
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Data from: Low levels of outdoor recreation alter wildlife behavior
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Long-term low-level nutrient additions significantly impact a low arctic mesic tundra plant community, but species responses differ from high-level fertilization: Implications for predicting climate warming impacts
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Database for Study: Shear-wave elastography for assessment of trapezius muscle stiffness: reliability and association with low-level muscle activity
<p>This is the database for the study entitled <strong>Shear-wave elastography for assessment of trapezius muscle stiffness: reliability and association with low-level muscle activity. </strong>In this study, we explored the reliability of shear-wave elastography for assessment of the trapezius muscle stiffness and its relationship with low-level muscle activity.Twenty participants were included in a two-session experiment. Measurements of shear modulus and muscle activity were performed at rest and during low-level activity, induced by shoulder abduction without additional external resistance. Good to excellent intra-session repeatability (ICC > 0.80) and moderate inter-rater and inter-session reproducibility (ICC = 0.66-0.74) were observed. Typical errors were acceptable only for intra-session measurements in resting conditions. Inverse relationships between shear modulus and muscle activity at 40° and 60° of shoulder abduction (r = -0.53 and -0.57) were observed on a group level. We also found lower shear modulus in females, for perpendicular probe position and for the non-dominant side of the body. Previous studies have demonstrated positive within-individual relationships between muscle activity and shear modulus. Our results suggested that, at least when the activity levels are low, an inverse relationship exists between muscle activity and shear modulus on a group level, suggesting inherent passive stiffness could account for a larger portion of the variance (compared to muscle activity) in shear modulus when the muscle activity is low. Our results imply that shear-wave elastography can be used in research exploring muscle stiffness, however, caution is needed since only intra-session examination in resting conditions showed acceptable within-participant typical errors.</p>
Analysis of well water level response to atmospheric loading from low- to high-frequency band
<p>Data used in manuscript "Analysis of well water level response to atmospheric loading from low- to high-frequency band"</p>
Data from: Chloroplast population genetics reveals low levels of genetic variation and conformation to the central–marginal hypothesis in Taxus wallichiana var. mairei, an endangered conifer endemic to China
The central–marginal hypothesis predicts that geographically peripheral populations should exhibit reduced genetic diversity and increased genetic differentiation than central populations due to smaller effective population size and stronger geographical isolation. We evaluated these predictions in the endangered conifer Taxus wallichiana var. mairei. Eight plastid simple sequence repeats (cpSSRs) were used to investigate plastid genetic variation in 22 populations of Taxus wallichiana var. mairei, encompassing nearly its entire distribution range. Low levels of plastid genetic variation and differentiation were detected in the populations, and the findings were attributed to low mutation rates, small population sizes, habitat fragmentation and isolation, and effective pollen or seed dispersal. Hunan and Hubei were identified as major refugia based on the number of private haplotypes and species distribution modeling. Trends in plastid genetic diversity and genetic differentiation from central to peripheral populations supported the predictions of the central–marginal hypothesis. In scenarios wherein the future climate becomes warmer, we predict that some peripheral populations will disappear and southern and southeastern regions will become significantly less habitable. Factors that include the levels of precipitation during the driest month, annual precipitation level, and annual temperature range will be decisive in shaping the future distribution of these populations. This study provides a theoretical basis for the conservation of T. wallichiana var. mairei.
Genotypes of 6 InDel markers for species identification from the Calanus culture at the EMBRC-ERIC laboratory for low-level trophic interactions, NTNU SeaLab
<p><span><span><span><span><span><span><span><span><span><span><span>Late developmental stages of marine copepods in the genus <i>Calanus</i> can spend extended periods in a dormant stage (diapause). During the growth season, copepods must accumulate sufficient lipid stores to survive diapause. Predation risk is often overlooked as a potential diapause-inducing cue. We tested experimentally if predation risk in combination with high or low food availability leads to differences in lipid metabolism, and potentially diapause initiation. Expression of lipid metabolism genes showed that food availability influences the copepods' ability to cope with predator stress. Predation caused upregulation of lipid catabolism with high food, and downregulation with low food. Stage development and molecular markers demonstrated that copepods did not enter diapause, instead, development occurred faster in copepods with predator stress. This study demonstrates that lipid metabolism may be a sensitive endpoint for changes in the environment. Our findings can contribute towards understanding the mechanisms behind diapause timing. </span></span></span></span></span></span></span></span></span></span></span></p>
Data from: Early life exposure to low levels of AHR agonist PCB126 (3,3',4,4',5-pentachlorobiphenyl) reprograms gene expression in adult brain
Early life exposure to environmental chemicals can have long-term consequences that are not always apparent until later in life. We recently demonstrated that developmental exposure of zebrafish to low, non-embryotoxic levels of 3,3',4,4',5-pentachlorobiphenyl (PCB126) did not affect larval behavior, but caused changes in adult behavior. The objective of this study was to investigate the underlying molecular basis for adult behavioral phenotypes resulting from early life exposure to PCB126. We exposed zebrafish embryos to PCB126 during early development and measured transcriptional profiles in whole embryos, larvae and adult male brains using RNA-sequencing. Early life exposure to 0.3 nM PCB126 induced cyp1a transcript levels in 2-dpf embryos, but not in 5-dpf larvae, suggesting transient activation of aryl hydrocarbon receptor with this treatment. No significant induction of cyp1a was observed in the brains of adults exposed as embryos to PCB126. However, a total of 2209 and 1628 genes were differentially expressed in 0.3 nM and 1.2 nM PCB126-exposed groups, respectively. KEGG pathway analyses of upregulated genes in the brain suggest enrichment of calcium signaling, MAPK and notch signaling, and lysine degradation pathways. Calcium is an important signaling molecule in the brain and altered calcium homeostasis could affect neurobehavior. The downregulated genes in the brain were enriched with oxidative phosphorylation and various metabolic pathways, suggesting that the metabolic capacity of the brain is impaired. Overall, our results suggest that PCB exposure during sensitive periods of early development alters normal development of the brain by reprogramming gene expression patterns, which may result in alterations in adult behavior.
Data from: Low levels of hybridization in two species of African driver ants
Hybridization in ants can have consequences different from those observed in most other species, with many of the potential deleterious effects being mitigated due to haplodiploidy and eusociality. In some species where colonies are either headed by multiple queens or single queens that mate with many males, hybridization is associated with genetic caste determination, where hybrids develop into workers and purebred individuals develop into queens. A previous study suggested that hybridization occurs between two Dorylus army ant species with multiply mate queens. However, the extent and exact pattern of hybridization has remained unclear, and its possible effect on caste determination has not been investigated. In this study we aimed to determine the extent and direction of hybridization by measuring how frequently hybrids occur in colonies of both species, and to investigate the possibility of genetic caste determination. We show that hybridization is bidirectional and occurs at equal rates in both species. Hybrid workers make up only 1-2% of the population, and interspecific matings represent approximately 2% of all matings in both species. This shows that, while interspecific matings that give rise to worker offspring occur regularly, they are much rarer than intraspecific mating. Finally, we find no evidence of an association between hybridization and genetic caste determination in this population. This means that genetic caste determination is not a necessary outcome of hybridization in ants, even in species where queens mate with multiple males.
Data and codes for figures in "Open water in sea ice causes high bias in polar low-level clouds in GFDL CM4"
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Multiscale large-eddy simulations of a low-level jet interacting with a wind farm and terrain (vertical slices of potential temperature)
<p>Multiscale large-eddy simulations of a low-level jet interacting with a wind farm and terrain (vertical slices of potential temperature) using the WRF-LES-GAD approach. Supplementary material part of the paper "Influence of simple terrain on the spatial variability of a low-level jet and wind farm performance in the AWAKEN field campaign", submitted to the Wind Energy Science journal.</p>
Multiscale large-eddy simulations of a low-level jet interacting with a wind farm and terrain (vertical slices of wind speed)
<p>Multiscale large-eddy simulations of a low-level jet interacting with a wind farm and terrain (vertical slices of wind speed) using the WRF-LES-GAD approach. Supplementary material part of the paper "Influence of simple terrain on the spatial variability of a low-level jet and wind farm performance in the AWAKEN field campaign", submitted to the Wind Energy Science journal.</p>
Multiscale large-eddy simulations of a low-level jet interacting with a wind farm and terrain (wind speed at 90 m AGL)
<p>Multiscale large-eddy simulations of a low-level jet interacting with a wind farm and terrain (wind speed at 90 m AGL) using the WRF-LES-GAD approach. Supplementary material part of the paper "Influence of simple terrain on the spatial variability of a low-level jet and wind farm performance in the AWAKEN field campaign", submitted to the Wind Energy Science journal.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.