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136 results for “phenotypic integration”
Data from: An integrated model of phenotypic trait changes and site-specific sequence evolution
Recent years have seen a constant rise in the availability of trait data, including morphological features, ecological preferences, and life history characteristics. These phenotypic data provide means to associate genomic regions with phenotypic attributes, thus allowing the identification of phenotypic traits associated with the rate of genome and sequence evolution. However, inference methodologies that analyze sequence and phenotypic data in a unified statistical framework are still scarce. Here, we present TraitRateProp, a probabilistic method that allows testing whether the rate of sequence evolution is associated with a binary phenotypic character trait. The method further allows the detection of specific sequence sites whose evolutionary rate is most noticeably affected following the character transition, suggesting a shift in functional/structural constraints. TraitRateProp is first evaluated in simulations and then applied to study the evolutionary process of plastid plant genomes upon a transition to a heterotrophic lifestyle. To this end, we analyze 25 plastid genes across 85 orchid species, spanning different lifestyles and representing different genera in this large family of flowering plants. Our results indicate higher evolutionary rates following repeated transitions to a heterotrophic lifestyle in all but four of the loci analyzed.
Cardiovascular, Pulmonary, and Integrative Functional Phenotypes in COVID-19 Survivors - Effect of Fenofibrate
ClinicalTrials.gov study NCT05080192. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Convergent evolution of phenotypic integration and its alignment with morphological diversification in Carribean Anolis ecomorphs
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Data from: Relaxed predation results in reduced phenotypic integration in a suite of dragonflies
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Data from: Integrating genomic and phenotypic data to evaluate alternative phylogenetic and species delimitation hypotheses in a recent evolutionary radiation of grasshoppers
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Data from: The effects of male social environment on sperm phenotype and genome integrity
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Data from: Phenotypic integration of the cervical vertebrae in the Hominoidea (Primates)
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Data from: The evolution of phenotypic integration: how directional selection reshapes covariation in mice
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Data from: Testing the link between phenotypic evolution and speciation: an integrated paleontological and phylogenetic analysis
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Data from: An integrated model of phenotypic trait changes and site-specific sequence evolution
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Data from: Phenotypic and genetic integration of personality and growth under competition in the sheepshead swordtail, Xiphophorus birchmanni
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Data from: Ontogenetic and stratigraphic influence on observed phenotypic integration in the limb skeleton of a fossil tetrapod
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Integrated transcriptional and phenotypic analysis of peripheral blood to capture the immunomodulating properties of pazopanib in rena; cell carcinoma patients
GEO Series GSE146163. Homo sapiens. 23 samples. Type: Expression profiling by array.
Integrative Proteome, Transcriptome and DNA Methylome Analysis of Regulatory Networks During U937-derived Macrophage Polarization from an M2 to M1 Phenotype [array]
GEO Series GSE127981. Homo sapiens. 6 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Integrative analysis of the lncRNA-miRNA-mRNA Interactions in Smooth Muscle Cell Phenotypic Transitions II
GEO Series GSE249983. Mus musculus. 12 samples. Type: Non-coding RNA profiling by array.
Integrative Proteome, Transcriptome and DNA Methylome Analysis of Regulatory Networks During U937-derived Macrophage Polarization from an M2 to M1 Phenotype
GEO Series GSE128007. Homo sapiens. 14 samples. Type: Expression profiling by array; Non-coding RNA profiling by array; Methylation profiling by high throughput sequencing.
Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer
GEO Series GSE188548. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Integrative genotyping of cancer and immune phenotypes by long-read sequencing
GEO Series GSE243227. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
Integration of M. tuberculosis phenotype with single cell RNA-seq to interrogate host macrophage heterogeneity in vivo.
GEO Series GSE167232. Mus musculus; Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
A molecular and phenotypic integrative approach to identify a no effect dose level for anti-androgen induced testicular toxicity
GEO Series GSE28202. Rattus norvegicus. 42 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.