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2,245 results for “risk factors”
Risk factors modifying familial aggregation for lung cancer in affected individuals
<p>Base de Datos</p>
Associations of serum uric acid with cardiovascular disease risk factors: a retrospective cohort study in Southeastern China
<p class="MsoNormal"><span>Objective: To evaluate the associations between serum uric acid (SUA) levels and cardiovascular disease (CVDs) risk factors, focusing on potential sex-specific differences.</span></p> <p class="MsoNormal"><span>Design: A retrospective cohort study.</span></p> <p class="MsoNormal"><span>Setting: A large community-based survey was conducted every two years from 2010 to 2018 in Hangzhou, Zhejiang Province, Southeastern China.</span></p> <p class="MsoNormal"><span>Participants: 6119 participants aged 40 years and above who underwent at least three times of physical examinations were enrolled. </span></p> <p class="MsoNormal"><span>Methods: Participants were categorized into four groups (Q1-Q4) based on baseline SUA quartiles within the normal range, with hyperuricemia (HUA) as the fifth group. The Q1 was the reference. By stratifying participants by gender, the relationships between SUA levels and systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), and total cholesterol (TC) were investigated using linear regression models in the generalized estimating equation (GEE). Additionally, the associations of elevated SUA levels and HUA with hypertension, hyperglycemia, and dyslipidemia were correspondingly examined using multivariate logistic regression models.</span></p> <p class="MsoNormal"><span>Results: After adjusting for confounding variables, we found positive associations between SUA levels and SBP, DBP, FBG, and TC in women, and with TC in men (P < 0.01). Likewise, Elevated SUA quartiles and HUA were linked to increased dyslipidemia risk in both sexes, and increased hyperglycemia risk only in women, with HRs (95%CI) of 1.64 (1.05-2.55) and 2.37 (1.47-3.81) in the Q4 and HUA group, respectively. Women with HUA had higher hypertension risk (HR=1.45, 95% CI 1.21-1.73), while no such association was observed in men. Stratified analyses revealed significant associations between elevated SUA levels and CVDs risk factors in postmenopausal and non-obese women.</span></p> <p class="MsoNormal"><span>Conclusions: Elevated SUA levels increase the risk of dyslipidemia in both sexes. SUA levels within normal-range and HUA are positively associated with hyperglycemia and hypertension in postmenopausal women, but not in men.</span></p>
Emergent factors of cardiovascular risk epidemiology and global cardiovascular risk
<p><strong>Introduction:</strong> Risk factors determine important clinical implications for cardiovascular prevention. <strong>Objective:</strong> Determine the epidemiology of emerging cardiovascular risk factors and global cardiovascular risk. Method: an observational, analytical, longitudinal and retrospective, case/control investigation was carried out from the individuals evaluated in the cardiology clinic of the Darío Calzadilla Angulo Polyclinic, Banes municipality, Holguín province during May 2021- May 2022. By sampling simple random, the sample was obtained (113 cases). The bioethical requirements were met. Inclusion/exclusion criteria were applied. The following statisticians were used: Chi square, Odd Ratio (OR), including p and confidence interval. The variables were operationalized: sex, age, risk factors, cardiovascular disease, and global cardiovascular risk. The control group was formed at a ratio of 2:1. <strong>Results:</strong> The age groups 60-69 years and 40-49 years prevailed. The female sex predominated. The clinical forms of ischemic cardiomyopathy and arrhythmias had a higher incidence. The associated diseases expressed a significant statistical association for cardiovascular disease, with a predominance of arterial hypertension (OR=2.38), obesity (OR=1.64) and diabetes mellitus (OR=1.79); with increased risk. Emerging cardiovascular risk factors expressed a very significant statistical association for cardiovascular disease with a predominance of high triglyceride quantification values (X2=24.8 OR=3.93 95% CI (2.25;6.86) p=0.000). High global cardiovascular risk was more frequent. <strong>Conclusions:</strong> Emerging cardiovascular risk factors and global cardiovascular risk are mostly modifiable.</p><p><strong>Keyword:</strong> CARDIOVASCULAR DISEASE; EPIDEMIOLOGY; RISK FACTOR'S; GLOBAL CARDIOVASCULAR RISK</p>
Omega-3 for Depression and Other Cardiac Risk Factors - 2
ClinicalTrials.gov study NCT02021669. IPD Sharing: NO. Countries: 1. Publications: 1.
Dementia and Kidney Disease: Epidemiological Approaches to Risk Factors and Treatment Strategies
ClinicalTrials.gov study NCT07093684. IPD Sharing: NO. Countries: 1. Publications: 7.
Effect of a Unique Web-based Behaviour Change Program on Weight Loss and Cardiovascular Risk Factors
ClinicalTrials.gov study NCT01472276. IPD Sharing: Not stated. Countries: 1. Publications: 1.
α-lipoic Acid (ALA), Magnesium, Vitamin B6 and Vitamin D and Risk Factor for Pre-term Birth
ClinicalTrials.gov study NCT03952533. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
Prospective Multicenter Cohort Study Evaluating the Incidence and Risk Factors for Problem Gambling Among Young Adults With First-episode Psychosis
ClinicalTrials.gov study NCT05686772. IPD Sharing: NO. Countries: 1. Publications: 7.
The Prevalence and Risk Factors of Coagulopathy in Pediatric Epilepsy Surgery Patients
ClinicalTrials.gov study NCT05675254. IPD Sharing: NO. Countries: 1. Publications: 1.
Effect of Risk Factors Likely to Influence Immuno of Combined Hepatitis A & B Vacc vs Monovalent Hepatitis A & B Vacc
ClinicalTrials.gov study NCT00289731. IPD Sharing: YES. Countries: 3. Publications: 1.
Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL)
ClinicalTrials.gov study NCT04017754. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Prevalence and Risk Factors of Hyperkalemia in Non-Dialysis Chronic Kidney Disease Patients in Community
ClinicalTrials.gov study NCT06940414. IPD Sharing: YES. Countries: 1. Publications: 8.
Study of TAK-875 in Adults With Type 2 Diabetes and Cardiovascular Disease or Risk Factors for Cardiovascular Disease
ClinicalTrials.gov study NCT01609582. IPD Sharing: Not stated. Countries: 32. Publications: 2.
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
ClinicalTrials.gov study NCT05527509. IPD Sharing: NO. Countries: 1. Publications: 2.
Growth Mindset Psychoeducation for Modifiable Risk Factors for CMD
ClinicalTrials.gov study NCT03707522. IPD Sharing: NO. Countries: 1. Publications: 6.
A Proof-of-Activity Study With Orticumab in Subjects With Psoriasis and Cardiometabolic Risk Factors
ClinicalTrials.gov study NCT04776629. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso
ClinicalTrials.gov study NCT04695197. IPD Sharing: YES. Countries: 2. Publications: 1.
Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese Adolescents
ClinicalTrials.gov study NCT00858247. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors
ClinicalTrials.gov study NCT01331837. IPD Sharing: Not stated. Countries: 31. Publications: 1.
Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression
ClinicalTrials.gov study NCT01212900. IPD Sharing: Not stated. Countries: 1. Publications: 4.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.