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113 results for “sublethal”
Data from: Antagonistic responses of exposure to sublethal temperatures: adaptive phenotypic plasticity coincides with a reduction in organismal performance
A fitness benefit of phenotypic plasticity is the ability of an organism to survive short-term, deleterious environmental fluctuations. Yet, the influence of selection on plasticity in modulating shifts in phenotypic traits remains unclear. Short-term phenotypic plasticity in thermal tolerance traits is attained by exposure to sublethal hot or cold temperatures (i.e. the hardening response). Heat hardening is expected to buffer organisms from the unpredictability of extreme thermal fluctuations in the environment so as to minimize interruptions in activity and enhance survival. However, exposure to sublethal temperatures might entail other phenotypic costs that constrain or inhibit the prolonged use of hardening responses across longer timescales. Here, we estimated the onset of the heat hardening response, physiological and behavioral shifts during heat hardening, and geographic variation in heat hardening using tree lizards (Urosaurus ornatus). Peak heat hardening occurred 6h after exposure to sublethal temperatures. We found that both preferred body temperatures and locomotor performance diminished following exposure to sublethal temperatures, and performance levels did not approach pre-exposure levels until after the peak hardening response. We also found support for intraspecific variation in the hardening response along an environmental gradient, where populations in more thermally variable environments exhibited stronger plastic responses and populations with higher baseline heat tolerances exhibited weaker plastic responses. Sublethal temperature exposure might induce plasticity in thermal tolerance, however we have characterized other phenotypic shifts that might curtail chronic reliance on plasticity in thermal traits as a mechanism of responding to changes in thermal environments induced by climate warming.
Data from: Bacterial adaptation to sublethal antibiotic gradients can change the ecological properties of multitrophic microbial communities
Antibiotics leak constantly into environments due to widespread use in agriculture and human therapy. Although sublethal concentrations are well known to select for antibiotic-resistant bacteria, little is known about how bacterial evolution cascades through food webs, having indirect effect on species not directly affected by antibiotics (e.g. via population dynamics or pleiotropic effects). Here, we used an experimental evolution approach to test how temporal patterns of antibiotic stress, as well as migration within metapopulations, affect the evolution and ecology of microcosms containing one prey bacterium, one phage and two protist predators. We found that environmental variability, autocorrelation and migration had only subtle effects for population and evolutionary dynamics. However, unexpectedly, bacteria evolved greatest fitness increases to both antibiotics and enemies when the sublethal levels of antibiotics were highest, indicating positive pleiotropy. Crucially, bacterial adaptation cascaded through the food web leading to reduced predator-to-prey abundance ratio, lowered predator community diversity and increased instability of populations. Our results show that the presence of natural enemies can modify and even reverse the effects of antibiotics on bacteria, and that antibiotic selection can change the ecological properties of multitrophic microbial communities by having indirect effects on species not directly affected by antibiotics.
Data from: Combined exposure to sublethal concentrations of an insecticide and a fungicide affect feeding, ovary development and longevity in a solitary bee
Pollinators in agroecosystems are often exposed to pesticide mixtures. Even at low concentrations, the effects of these mixtures on bee populations are difficult to predict due to potential synergistic interactions. We orally exposed newly-emerged females of the solitary bee Osmia bicornis to environmentally-realistic levels of clothianidin (neonicotinoid insecticide) and propiconazole (fungicide), singly and in combination. The amount of feeding solution consumed was highest in bees exposed to the neonicotinoid, and lowest in bees exposed to the pesticide mixture. Ovary maturation and longevity of bees of the neonicotinoid and the fungicide treatments did not differ from those of control bees. In contrast, bees exposed to the pesticide mixture showed slow ovary maturation and decreased longevity. We found a synergistic interaction between the neonicotinoid and the fungicide on survival probability. We also found an interaction between treatment and emergence time (an indicator of physiological condition) on longevity. Longevity was negatively correlated to physiological condition only in the fungicide and the mixture treatments. Delayed ovary maturation and premature death imply a shortened nesting period (highly correlated to fecundity in Osmia). Our findings provide a mechanism to explain the observed dynamics of solitary bee populations exposed to multiple chemical residues in agricultural environments.
Changes in thermal sensitivity of tadpoles of Rhinella arenarum (Anura: Bufonidae) exposed to sublethal concentrations of different pesticide fractions (Lorsban® 75WG).
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Figure 1 in Sublethal effects of spiromesifen on life table traits ofTetranychus urticae (Acari: Tetranychidae) andNeoseiulus californicus (Acari: Phytoseiidae)
Figure 1 Age-stage survival rate (sx j) of two generations of Tetranychus urticaeexposed to LC20 of spiromesifen.
Data from: Sublethal streptomycin concentrations and lytic bacteriophage together promote resistance evolution
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Data from: Antagonistic responses of exposure to sublethal temperatures: adaptive phenotypic plasticity coincides with a reduction in organismal performance
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Data from: Predictors and immunological correlates of sublethal mercury exposure in vampire bats
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Data from: Combined exposure to sublethal concentrations of an insecticide and a fungicide affect feeding, ovary development and longevity in a solitary bee
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Data from: Parental sublethal insecticide exposure prolongs mating response and decreases reproductive output in offspring
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Data from: Bacterial adaptation to sublethal antibiotic gradients can change the ecological properties of multitrophic microbial communities
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Data from: Chronic impairment of bumblebee natural foraging behaviour induced by sublethal pesticide exposure
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Data from: Impact of sublethal exposure to a pyrethroid-neonicotinoid insecticide on mating, fecundity and development in the bed bug Cimex lectularius L. (Hemiptera: Cimicidae)
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Data from: The SOS response increases bacterial fitness, but not evolvability, under a sublethal dose of antibiotic
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Genome-wide transcriptomic profiling of cardiomyocyte differentiation from human ES cells and iPS cells under exposure to sublethal of isotretinoin (RNA-seq)
GEO Series GSE85880. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA sequencing of digested whole lungs of mb1Cre-/-ChATfl/fl and mb1Cre+/-Chatfl/fl mice taken before and at 24h after infection with a sublethal dose of Influenza A/Puerto Rico/8/24
GEO Series GSE290363. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Stress response in Escherichia coli following sublethal phenalene-1-one mediated antimicrobial photodynamic therapy: an RNA-Seq study
GEO Series GSE215798. Escherichia coli. 20 samples. Type: Expression profiling by high throughput sequencing.
Dose-dependent hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to sublethal doses of gamma radiation
GEO Series GSE59035. salmonid fish; Salmo salar. 16 samples. Type: Expression profiling by array.
Sublethal necroptosis signaling promotes inflammation and liver cancer
GEO Series GSE166875. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Responses of S. aureus to stress caused by sublethal concentration of cationic antimicrobial peptides
GEO Series GSE15800. Staphylococcus aureus. 12 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.