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728 results for “urine”
Automatic unsupported electromembrane extraction followed by on-line electrochemical detection of diclofenac in urine
<p>Raw voltammograms (including calibration) of data presented in Table 1 of the article entitled "Programmable millifluidic platform integrating automatic electromembrane extraction clean-up and in-line electrochemical detection: A proof of concept"<strong> </strong>published in ACS Sensors (<a href="https://doi.org/10.1021/acssensors.2c01648">10.1021/acssensors.2c01648</a>)</p>
Urinary metabolic dysregulations associated to thirdhand smoke exposure in mice: Implications for human urine biomonitoring
<p>This dataset contains all raw LC-MS and GC-MS data of urine extracts from mice exposed to thirdhand smoke (THS) used in the paper<em> Urinary metabolic dysregulations associated to thirdhand smoke exposure in mice: Implications for human urine biomonitoring</em>.</p> <p><strong>Objective:</strong> The goal of this study is to characterize the THS-induced molecular alterations in urine using an LC-MS and GC-MS based untargeted metabolomic approaches. We have selected urine as a target matrix because it is a non-invasive valuable diagnostic biofluid, rich in metabolites that reflect dysregulations of all biochemical pathways, which also has been one of the most widely used biofluid to assess human exposure to tobacco smoke.</p> <p><strong>Experimental groups:</strong> Urine extracts were from two mice groups: control group (CTRL, n=5), which was never exposed to THS; and THS exposed group (THS, n=5), which was exposed to THS from weaning (three weeks of age) to 24 weeks weeks without exposure to SHS during the study.</p> <p><strong>Sample extraction:</strong> Metabolites were extracted using a mixture of methanol and Milli-Q water. In the case of GC-MS, samples were pre-treated with urease prior metabolite extraction and dried under nitrogen, lyophilized, and derivatized after extraction. Quality control samples (QCs) were prepared by pooling equal volumes of each extract and analysed every five samples to ensure data quality and reproducibility.</p> <p><strong>LC-MS analysis: </strong>LC-MS urine extracts were analysed using a 1290 UHPLC system coupled to a 6550 quadrupole time of flight (QTOF) mass spectrometer from Agilent Technologies operated in ESI+ mode. Chromatographic separation was conducted on a ACQUITY UPLC HSS T3 C18 column (1.8 µm, 150 × 2.1 mm, Waters). MS/MS was performed in targeted mode, and the instrument was set to acquire over the m/z range 50-1000, with a default iso width of 4 m/z. The collision energy was fixed at 20 V.</p> <p><strong>GC-MS analysis:</strong> GC-MS urine extracts were analysed using a 7890A gas chromatograph coupled to a 7200 QTOF mass spectrometer from Agilent Technologies. The MS was operated in the electron impact ionization mode at 70 eV, with a fixed emission current of 20 µA.</p> <p><strong>Files are named following this code:</strong></p> <ol> <li><strong>Folders: </strong>mzDATA: contains GC-MS and LC-MS raw data in mzXML format; LC-MSMS: contains LC-MS/MS data used for identification of metabolites in mzXML format.</li> <li><strong>Analytical approaches:</strong> GCMS: data from GC-MS urine extracts; LCMS: data from LC-MS urine extracts.</li> <li><strong>Samples: </strong>CTRL: control group; THS: THS exposed group.</li> </ol> <p><strong>Technical information</strong></p> <ol> <li>Sample extraction and data acquisition (single date, range, approximate date): 2016-2017</li> <li>Data analysis (single date, range, approximate date): 2017-2021</li> <li>Geographic location of data collection: <ul> <li>Mice exposure: Department of Molecular, Cell and Systems Biology, University of California, Riverside CA 92521, U.S.A.</li> <li>Sample extraction and data acquisition: Universitat Rovira i Virgili, Departament d’Enginyeria Electrònica, Elèctrica i Automàtica, Tarragona, Spain.</li> </ul> </li> <li>Information about funding sources that supported the collection of the data: This research was funded by the European Union’s Horizon 2020 research and innovation pro-gramme under the Marie Sklodowska-Curie grant agreement No. 660034; the Secretaria d’Universitats i Recerca del Departament d’Empresa i Coneixement de la Generalitat de Catalunya through C.M.’s predoctoral grant number 2020 FI_B2 00118; the Spanish Ministry of Science & Innovation through N.R.’s Juan de la Cierva Incorporación grant No. (IJCI- 2015-23158); N.R.’s Miguel Servet contract (CP19/00060) from Instituto de Salud Carlos III, co-financed by Fondo Europeo de Desarrollo Regional (FEDER), Unión Europea, “Una manera de hacer Europa”; and the Tobacco-Related Disease Research Program (TRDRP) of the University of California under projects 22RT- 0121 and 23DT-0103.</li> </ol>
1H-NMR-based urine metabolomics of prostate cancer and benign prostatic hyperplasia
<p>This dataset was collected from patients diagnosed with prostate cancer (R-sample_number) and benign prostatic hyperplasia (T-sample_number) using 1H-NMR spectroscopy.</p> <p>For more details check our paper: https://doi.org/10.1016/j.heliyon.2024.e28949</p>
Effect of Urine Alkalinazation on Urinary Inflammatory Markers in Patients With Cystinuria
ClinicalTrials.gov study NCT03836144. IPD Sharing: NO. Countries: 1. Publications: 2.
PrevenTion of Contrast-inducEd nephroAThy With urinE Alkalinization
ClinicalTrials.gov study NCT02980003. IPD Sharing: NO. Countries: 1. Publications: 5.
Ethyl Glucuronide in Urine Samples of Pregnant Women Within the HUS ja PHHYKY Area
ClinicalTrials.gov study NCT04571463. IPD Sharing: YES. Countries: 1. Publications: 1.
Prevent Inability To Control Urination
ClinicalTrials.gov study NCT00075114. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Effect of Non-invasive Bladder Stimulation Technique on Collecting Urine Specimen in Infants Under One Year Old
ClinicalTrials.gov study NCT05394454. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Comparison Between Effects of Two Iron Preparations on Protein in the Urine
ClinicalTrials.gov study NCT00534144. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Risk Factors for Pediatric Emergence Agitation and Analysis of Serum or Urine Metabonomics in Children With Agitation
ClinicalTrials.gov study NCT04807998. IPD Sharing: NO. Countries: 1. Publications: 1.
Urin-based Point-of-Care Testing for Direct Oral Anticoagulants in Stroke Patients
ClinicalTrials.gov study NCT06037200. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Urine Iodine Levels of Surgical Staff
ClinicalTrials.gov study NCT03845777. IPD Sharing: NO. Countries: 1. Publications: 3.
Multimodal Spectroscopy to Detect Urothelial Cancer in Urine
ClinicalTrials.gov study NCT04718948. IPD Sharing: NO. Countries: 1. Publications: 1.
Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING PUMA)
ClinicalTrials.gov study NCT06423612. IPD Sharing: YES. Countries: 1. Publications: 6.
Urine Metabolites in the Diagnosis of Disease
ClinicalTrials.gov study NCT06710067. IPD Sharing: NO. Countries: 1. Publications: 5.
Diagnosis of Pancreatic Cancer by Purine Metabolite (Hypoxanthine, Xanthine) in Urine
ClinicalTrials.gov study NCT06291779. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Effect of Bladder Stimulation Technique on Urine Specimen Collection in Newborns
ClinicalTrials.gov study NCT05416736. IPD Sharing: Not stated. Countries: 1. Publications: 14.
Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer
ClinicalTrials.gov study NCT07187063. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Cranberry Juice for Preventing Bacteria in Urine During Pregnancy
ClinicalTrials.gov study NCT00093938. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Urine Proteome of Surgical Patients and Healthy Volunteers
ClinicalTrials.gov study NCT01538823. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.