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ShareScore release 0.9.0
Dataset results
164 results for “vasculitis”
Hematopoietic Stem Cell Support in Vasculitis
ClinicalTrials.gov study NCT00278512. IPD Sharing: NO. Countries: 1. Publications: 0.
Single-cell transcriptional analysis of human pluripotent stem cell-derived heart epicardium-myocardium organoids uncover principals of human epicardial-derived cells specification and coronary vascul
GEO Series GSE309829. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Kidney transcriptomic profiling of immune-related genes in ANCA-associated vasculitis
GEO Series GSE298999. Homo sapiens. 224 samples. Type: Expression profiling by array.
Blood transcriptome indicates different disease etiology in pediatric ANCA-associated vasculitis subtypes.
GEO Series GSE129752. Homo sapiens. 52 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNAseq (10x Genomics) analysis of the abdominal aorta in a murine model of Kawasaki disease vasculitis
GEO Series GSE178765. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
The Role of FOXO4/NFAT2 Signaling Pathway in Dysfunction of Human Coronary Endothelial Cells and Inflammatory Infiltration of Vasculitis in Kawasaki Disease
GEO Series GSE210094. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Spatial transcriptomics (Visium, Spatial 3' V1, 10x Genomics) analysis of heart tissues in a murine model of Kawasaki disease vasculitis
GEO Series GSE178799. Mus musculus. 2 samples. Type: Other.
Spatial transcriptome landscape of systemic vasculitis
GEO Series GSE233214. Homo sapiens. 3 samples. Type: Other; Expression profiling by high throughput sequencing.
Comprehensive Profiling of Peripheral Blood Mononuclear Cells Reveals Monocyte-CD8+ T cell-B cell Communication as Central Cell-cell Interaction and pathogenesis in IgA Vasculitis
GEO Series GSE243002. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing; Other.
Focused transcription profiling of peripheral blood mononuclear cells from vasculitis patients
GEO Series GSE18247. Homo sapiens. 14 samples. Type: Expression profiling by array.
Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced exudative vasculitis and predicts COVID-19 severity
GEO Series GSE208337. Homo sapiens. 105 samples. Type: Expression profiling by high throughput sequencing; Other.
Data from: Exploratory proteomic analysis implicates the alternative complement cascade in Primary CNS Vasculitis
Objective: To identify molecular correlates of primary angiitis of the central nervous system (PACNS) through proteomic analysis of cerebrospinal fluid (CSF) from a biopsy-proven patient cohort. Methods: Using mass spectrometry, the CSF proteome of biopsy-proven PACNS patients (n=8) was quantitatively compared to CSF from individuals with non-inflammatory conditions (n=11). Significantly enriched molecular pathways were identified using a gene ontology workflow, and high confidence hits within enriched pathways (fold change >1.5 and concordant Benjamini-Hochberg-adjusted p-value <0.05 on DeSeq and t-test) were identified as differentially regulated proteins. Results: Compared to non-inflammatory controls, 283 proteins were differentially expressed in PACNS patient CSF, with significant enrichment of the complement cascade pathway (C4-binding protein, CD55, CD59, properdin, complement C5, complement C8 and complement C9) and neural cell adhesion molecules. A subset of clinically relevant findings was validated by western blot and commercial ELISA. Conclusions: In this exploratory study we found evidence of deregulation of the alternative complement cascade in CSF from biopsy-proven PACNS as compared to non-inflammatory controls. More specifically, several regulators of the C3 and C5 convertases and components of the terminal cascade were significantly altered. These preliminary findings shed light on a previously unappreciated similarity between PACNS and systemic vasculitides, especially Anti-Neutrophil Cytoplasmic Antibody (ANCA)-associated vasculitis. The therapeutic implications of this common biology, and the diagnostic and/or therapeutic utility of individual proteomic findings warrant validation in larger cohorts.
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
ClinicalTrials.gov study NCT06072482. IPD Sharing: YES. Countries: 5. Publications: 0.
Rituximab Plus Corticosteroids in Non-infectious Active Mixed Cryoglobulinemia Vasculitis
ClinicalTrials.gov study NCT02556866. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Early-access Avacopan in Real-world ANCA-associated Vasculitis
ClinicalTrials.gov study NCT06794827. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
PRO Development for ANCA Associated Vasculitis
ClinicalTrials.gov study NCT01729624. IPD Sharing: Not stated. Countries: 1. Publications: 0.
PRagmatic Analysis of Vitamin D in ANCA-Associated Vasculitis
ClinicalTrials.gov study NCT04280601. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluate the Remission MAINtenance Using Extended Administration of Prednisone in Systemic Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis.
ClinicalTrials.gov study NCT03290456. IPD Sharing: NO. Countries: 1. Publications: 0.
Reproductive Health in Men and Women With Vasculitis
ClinicalTrials.gov study NCT02176070. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pediatric ANCA Associated-vasculitis
ClinicalTrials.gov study NCT05383573. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.