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restrictedIPD-UNDECIDEDFeb 2026View details →

Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder

ClinicalTrials.gov study NCT01430754. IPD Sharing: Not stated. Countries: 1. Publications: 1.

closedIPD-NOFeb 2026View details →

The Clinical Utility of Measuring the Circadian Clock in Treatment of Delayed Sleep-Wake Phase Disorder

ClinicalTrials.gov study NCT03715465. IPD Sharing: NO. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →

Efficacy and Safety of Tasimelteon Compared With Placebo in Totally Blind Subjects With Non-24-Hour Sleep-Wake Disorder

ClinicalTrials.gov study NCT01163032. IPD Sharing: Not stated. Countries: 2. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →

Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention With Trevo

ClinicalTrials.gov study NCT02142283. IPD Sharing: Not stated. Countries: 5. Publications: 6.

dryad36/100

Data from: Plasma refilling of the lunar wake: Plasma-vacuum interactions, electrostatic shocks, and electromagnetic instabilities

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publicJul 2025View details →

dryad36/100

Hovering flight in hummingbird hawkmoths: Kinematics, wake dynamics and aerodynamic power

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publicMay 2021View details →

dryad36/100

NREM sleep EEG and wake ERP summary: The first wave of the Global Research Initiative on the neurophysiology of schizophrenia (GRINS)

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publicMay 2022View details →

opencc-by-4.0Jul 2020View details →

Dataset for Supersaturation in the Wake of a Precipitating Hydrometeor and its Impact on Aerosol Activation

******************Dataset Details****************** 1. Article Title: Supersaturation in the Wake of a Precipitating Hydrometeor and its Impact on Aerosol Activation 2. Journal: Geophysical Research Letters, 47(22),  e2020GL091179, <a href="https://doi.org/10.1029/2020GL091179">https://doi.org/10.1029/2020GL091179</a>, 2020 3. Name and contact information:     Eberhard Bodenschatz,     Laboratory for Fluid Physics, Pattern Formation and Biocomplexity,     Max Planck Institute for Dynamics and Self-Organization,     Am Faßberg 17,     37077 Göttingen, Germany 4. Email: eberhard.bodenschatz@ds.mpg.de 5. Funding: This research was funded by the Marie - Sk lodowska Curie Actions (MSCA) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 675675), and an extension to programme COMPLETE by Department of Applied Science and Technology, Politecnico di Torino. 6. Abstract: The activation of aerosols impacts the life cycle of a cloud. A detailed understanding is necessary for reliable climate prediction. Recent laboratory experiments demonstrate that aerosols can be activated in the wake of precipitating hydrometeors. However, many quantitative aspects of this wake‐induced activation of aerosols remain unclear. Here, we report a detailed numerical investigation of the activation potential of wake‐induced supersaturation. By Lagrangian tracking of aerosols, we show that a significant fraction of aerosols are activated in the supersaturated wake. These “lucky aerosols” are entrained in the wake's vortices and reside in the supersaturated environment sufficiently long to be activated. Our analyses show that this wake‐induced activation of aerosols can contribute to the life cycle of the clouds. ******************Dataset Organization****************** 1. Datasets are organized in folders which correspond to Figures in the Letter or in the Supporting Information (e.g., Figure 1 or Figure S2). 2. Details of the entries can be found in the header of each dataset. 3. Details of the simulation setup can be found in the text of each Figure. ******************Software Details****************** 1. Open-source  LBM  library  Palabos  (Latt  et al., 2020). Link: https://palabos.unige.ch/ 2. Data visualization is achieved using open-source library ParaView version 5.7 and Gnuplot Version 5.2.

opencc-zeroAug 2020View details →

Velocity vector files from PIV measurements of the wake behind a flying beetle

These are the velocity vector files from the PIV measurements in the wake of Batocera rufomaculata flying tethered in a wind tunnel. The data correspond to the manuscript: The aerodynamics and power requirements of forward flapping flight in the mango stem borer beetle (Batocera rufomaculata), by Urca et al. published by the journal Integrative Organismal Biology. The abstract of the coresponding paper is: The need for long dispersal flights can drive selection for behavioral, physiological and biomechanical mechanisms to reduce the energy spent flying. However, some energy loss during the transfer of momentum from the wing to the fluid is inevitable, and inherent to the fluid-wing interaction. Here, we analyzed these losses during the forward flight of the mango stem borer (Batocera rufomaculata). This relatively large beetle can disperse substantial distances in search of new host trees, and laboratory experiments have demonstrated continuous tethered flights that can last for up to an hour. We flew the beetles tethered in a wind tunnel and used high-speed videography to estimate the aerodynamic power from their flapping kinematics and particle image velocimetry (PIV) to evaluate drag and kinetic energy from their unsteady wakes. To account for tethering effects, we measured the forces applied by the beetles on the tether arm holding them in place. The drag of the flying beetle over the flapping cycle, estimated from the flow fields in the unsteady wake, showed good agreement with direct measurement of mean horizontal force. Both measurements showed that total drag during flight is ~5-fold higher than the parasite drag on the body. The aerodynamic power estimated from both the motion of the wings, using a quasi-steady blade-element model, and the kinetic energy in the wake, gave mean values of flight-muscle mass-specific power of 87 and 65 W kg muscle-1, respectively. A comparison of the two values suggests that ~25% of the energy is lost within the fluid due to turbulence and heat. The muscle mass-specific power found here is low relative to the maximal power output reported for insect flight muscles. This can be attributed to reduced weight support during tethered flight or to operation at submaximal output that may ensure a supply of metabolic substrates to the flight muscles, thus delaying their fatigue during long-distance flights.

opencc-zeroDec 2014View details →

Data from: Competition in slow motion: the unusual case of benthic marine communities in the wake of the end-Permian mass extinction

Changes of community structure in response to competition usually take place on timescales that are much too short to be visible in the geological record. Here we report the notable exception of a benthic marine community in the wake of the end-Permian mass extinction, which is associated with the microbial limestone facies of the earliest Triassic of South China. The newly reported fauna is well preserved and extraordinarily rich (30 benthic macroinvertebrate species, including the new species Astartella? stefaniae (Bivalvia) and Eucochlis obliquecostata (Gastropoda)) and stems from an environmentally stable setting providing favourable conditions for benthic organisms. Whereas changes in the taxonomic composition are negligible over the observed time interval of 10–100 ka, three ecological stages are identified, in which relative abundances of initially rare species continuously increased at the cost of previously dominant species. Concomitant with the changes of dominant species is an increase in faunal evenness and heterogeneity. In the absence of both environmental and taxonomic changes, we attribute this pattern to the long-term effects of interspecific competition, which acted at an unusually slow pace because the number of competing species and potential immigrants was dramatically reduced by the end-Permian mass extinction. We suggest that these non-actualistic conditions led to decreased rates of niche differentiation and hence to the delayed rediversification of benthos that characterizes the aftermath of the greatest Phanerozoic mass extinction event. A hyperbolic diversification model is proposed, which accounts for the positive relationship between the intensity of interspecific competition and the rate of niche differentiation and resolves the conundrum of delayed rediversification at a time when niche space was largely vacated.

opencc-zeroDec 2015View details →

Data from: Litter microbial and soil faunal communities stimulated in the wake of a volcanic eruption in a semi-arid woodland in Patagonia, Argentina

Large-scale disturbances can be important components of the temporal landscape of natural ecosystems, but generalities regarding ecosystem impacts are difficult due to their infrequent and unpredictable nature. Volcanic eruptions figure as one of the most prominent of these natural disturbances, but the effects on microbes and ground-dwelling arthropods, which modulate carbon and nutrient turnover, are relatively unknown. We evaluated the effects of the 2011 Puyehue-Cordón Caulle eruption in Patagonia, Argentina, on the litter and soil microbial and faunal communities in natural and afforested semi-arid ecosystems located 70 km west of the epicentre of the eruption. We hypothesized that volcanic ash deposition would strongly reduce soil faunal and microbial communities due to insecticidal effects of ash on arthropods, with a concomitant reduction in ecosystem processes. Our objective was to quantify the impact of the volcanic eruption by comparing pre- and post-eruption time points in the same study site, with nearly identical field methodology. We measured environmental variables of soil and litter moisture, pH, microbial biomass, and soil and litter microbial enzymatic activity. We evaluated ground-dwelling arthropods and nematodes using pitfall traps and soil extraction, respectively. Additionally, a parallel, controlled-condition experiment of simulated ash deposition was conducted to evaluate ash effects on litter decomposition and enzymatic activity. In the field, post-eruption soils had lower soil water content, pH and soil organic matter. Additionally, nematode abundance and soil microbial enzyme activity were significantly reduced. In contrast, ground-dwelling arthropods and litter enzymatic activity increased significantly. Finally, with simulated ash deposition, litter decomposition increased fourfold for native litter decomposition. Large-scale disturbances may play a key role in biogeochemical cycling in affected natural ecosystems, but not necessarily due to their catastrophic effects. In contrast to our original predictions, we observed a marked stimulation of biotic activity and carbon turnover in the aftermath of the Puyehue volcanic eruption, which demonstrates that the biotic component of these ecosystems has a substantial capacity to respond to these disturbances in short time frames. These results can contribute to placing the role of these large-scale infrequent disturbances in a more robust ecological context.

opencc-zeroDec 2017View details →

Data from: Hawkmoth flight in the unsteady wakes of flowers

Flying animals maneuver and hover through environments where wind gusts and flower wakes produce unsteady flow. Although both flight maneuvers and aerodynamic mechanisms have been studied independently, little is known about how these interact in an environment where flow is already unsteady. Moths forage from flowers by hovering in the flower's wake.We investigated hawkmoths tracking a 3D-printed robotic flower in a wind tunnel.We visualized the flow in the wake and around the wings and compared tracking performance with previous experiments in a still-air flight chamber. As in still air, moths flying in the flower wake exhibit near-perfect tracking at low frequencies where natural flowers move. However, tracking in the flower wake results in a larger overshoot between 2 and 5 Hz. System identification of flower tracking reveals that moths also display reduced-order dynamics in wind compared with still air. Smoke visualization of the flower wake shows that the dominant vortex shedding corresponds to the same frequency band as the increased overshoot. Despite these large effects on tracking dynamics in wind, the leading edge vortex (LEV) remains bound to the wing throughout the wingstroke and does not burst. The LEV also maintains the same qualitative structure seen in steady air. Persistence of a stable LEV during decreased flower tracking demonstrates the interplay between hovering and maneuvering.

FIGURE 16 in A revision of the Hawaiian and Wake Island species of the genus Conchopus Takagi (Diptera, Dolichopodidae)

FIGURE 16. Conchopus pacificus sp. nov., male abdominal sterna: (a) 1st (top) to 5th (bottom); (b) pedunculate process in lateral view; (c) sternum 6.

FIGURE 18 in A revision of the Hawaiian and Wake Island species of the genus Conchopus Takagi (Diptera, Dolichopodidae)

FIGURE 18. Male wings of species of Conchopus: (a) Conchopus acrosticalis (Parent); (b) Conchopus ciliatus sp. nov.; (c) Conchopus crassinervis sp. nov.; (d) Conchopus minutus sp. nov.; (e) Conchopus menehune sp. nov.; (f) Conchopus pacificus sp. nov.

FIGURE 14 in A revision of the Hawaiian and Wake Island species of the genus Conchopus Takagi (Diptera, Dolichopodidae)

FIGURE 14. Conchopus menehune sp. nov., (a) ventral lobe; (b) cercus; (c) hypandrium in lateral view; (d) hypandrium in dorsal view.

FIGURE 15 in A revision of the Hawaiian and Wake Island species of the genus Conchopus Takagi (Diptera, Dolichopodidae)

FIGURE 15. Conchopus pacificus sp. nov., legs of male: (a) left foreleg in posterior view; (b) distal part of tibia, tarsal segments 1–2 of right foreleg in anterior view; (c) left middle femur in anterior view.

FIGURE 13 in A revision of the Hawaiian and Wake Island species of the genus Conchopus Takagi (Diptera, Dolichopodidae)

FIGURE 13. Conchopus menehune sp. nov., legs of male: (a) distal part of tibia, tarsal segments 1–2 of left foreleg in posterior view; (b) right foreleg in anterior view.

FIGURE 12 in A revision of the Hawaiian and Wake Island species of the genus Conchopus Takagi (Diptera, Dolichopodidae)

FIGURE 12. Conchopus minutus sp. nov., male genitalia: (a) hypopygium; (b) ventral lobe; (c) cercus; (d) hypandrium in lateral view; (e) hypandrium in dorsal view.

FIGURE 11 in A revision of the Hawaiian and Wake Island species of the genus Conchopus Takagi (Diptera, Dolichopodidae)

FIGURE 11. Conchopus minutus sp. nov., male abdominal sterna: (a) 1st (top) to 5th (bottom); (b) pedunculate process in lateral view; (c) sternum 6.

FIGURE 10 in A revision of the Hawaiian and Wake Island species of the genus Conchopus Takagi (Diptera, Dolichopodidae)

FIGURE 10. Conchopus minutus sp. nov., legs of male: (a) left foreleg in posterior view; (b) distal part of tibia, tarsal segments 1–2 of right foreleg in anterior view; (c) left middle femur in anterior view.