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2,009 results for “Disruption”

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geo24/100

A mixture of chemicals found in human amniotic fluid disrupts brain gene expression and behavior in Xenopus laevis

GEO Series GSE223829. Xenopus laevis. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2023View details →
geo24/100

HDAC5 Deficiency Induces Intrinsic Resistance to KRASG12D Inhibition by Disrupting c-Myc Acetylation-Ubiquitination Homeostasis [RNA-seq]

GEO Series GSE309499. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo24/100

Rorc disruption in human FG pancreatic cancer cells

GEO Series GSE126537. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2019View details →
geo24/100

Limb reduction in an Esco2 cohesinopathy mouse model is mediated by p53-dependent apoptosis and vascular disruption [scRNA-Seq]

GEO Series GSE230492. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo24/100

Astrocyte-Derived Clusterin Disrupts Glial Physiology to Obstruct Remyelination in Mouse Models of Demyelinating Diseases

GEO Series GSE275514. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo24/100

Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease

GEO Series GSE60487. Mus musculus; Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2014View details →
geo24/100

Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy due to sarcomere disruption and protein aggregate formation

GEO Series GSE166862. Mus musculus. 234 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2021View details →
geo24/100

Mitochondrial dysfunction, disruption of F-actin polymerization, and transcriptomic alterations in zebrafish larvae exposed to trichloroethylene

GEO Series GSE72918. Danio rerio. 8 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2016View details →
geo24/100

Prolonged FOS Activity Disrupts A Global Myogenic Transcriptional Program By Altering 3D Chromatin Architecture in Primary Muscle Progenitor Cells

GEO Series GSE166241. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo24/100

Transcriptional alteration in malaria parasite after disruption of PfPRMT5 [Array]

GEO Series GSE199419. Plasmodium falciparum. 24 samples. Type: Expression profiling by array.

openGEO-OpenJun 2023View details →
geo24/100

Disruption of dNTPs Homeostasis by Ribonucleotide Reductase Hyperactivation Overcomes AML Differentiation Blockade

GEO Series GSE193721. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2023View details →
geo24/100

Loss of 3-O-sulfotransferase enzymes, Hs3st3a1 and Hs3st3b1, reduces kidney and glomerular size and disrupts glomerular architecture

GEO Series GSE261059. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo24/100

Klf4 gene disruption is linked to enhanced cellular proliferation and tumor formation

GEO Series GSE21768. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenNov 2010View details →
geo24/100

Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation

GEO Series GSE67931. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2016View details →
geo24/100

Disruption of GRIN2B impairs differentiation in human neurons

GEO Series GSE114685. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2018View details →
geo24/100

BET inhibition disrupts transcription but retains enhancer-promoter contact

GEO Series GSE139437. Homo sapiens. 77 samples. Type: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenOct 2020View details →
geo24/100

Ribosome biogenesis disruption mediated chromatin structure changes in C. elegans larvae revealed by SRAtac, an integrated, customizable end to end analysis pipeline for ATAC-seq

GEO Series GSE218280. Caenorhabditis elegans. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2022View details →
geo24/100

Tet inactivation disrupts YY1 binding and long-range chromatin interactions to cause developmental defects in embryonic heart

GEO Series GSE121671. Mus musculus; Homo sapiens. 23 samples. Type: Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other.

openGEO-OpenAug 2019View details →
geo24/100

Activation of alveolar epithelial ER stress by b-coronavirus infection disrupts surfactant homeostasis in mice: implications for COVID-19 respiratory failure

GEO Series GSE244820. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2024View details →
geo24/100

Cancer cells with genetic disruption of DNA methyltransferases

GEO Series GSE93136. Homo sapiens. 48 samples. Type: Methylation profiling by genome tiling array; Expression profiling by array.

openGEO-OpenJan 2017View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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