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7,518 results for “screenings”
Screen of ESK1 TCR mimic antibody against a library of HLA-A*02:01 MHC-I peptides
<p>Minigene sequencing of T2 cells sorted for high and low binding to the TCR mimic antibody "ESK1."</p>
Microscope Image Analysis Course Sept 2109 -- Images siRNA Screen
<p>Contains 380 Fluorescence images of DAPI stained HeLa nuclei, acquired in 42 wells of a 384 well plate. individual wells were treated with siRNA. Images were acquired with an Olympus ScanR system at 10x magnification.</p>
Microscope Image Analysis Course Sept 2109 -- Images siRNA Screen
<p>Contains 380 Fluorescence images of DAPI stained HeLa nuclei, acquired in 42 wells of a 384 well plate. individual wells were treated with siRNA. Images were acquired with an Olympus ScanR system at 10x magnification.</p>
Buffer screen by DSLS of C-HEAT and N-HEAT domains
<p>Raw data and summary of results of DSLS data recorded for C-HEAT_2088-3144 (TOC019 C01), and constructs of the N-HEAT domain: N-HEAT_76-404 (TOC019 B02), N-HEAT_93-404 (TOC019 A03), <a href="https://zenodo.org/record/3462496#.XY4U1mYpA2x">N-HEAT_81-1643 (TOC019 B08)</a>, N-HEAT_76-1715 (TOC019 A08).</p>
Identification of Mitoxantrone as a Potent Inhibitor of Transcriptional Cyclin-Dependent Kinase 7 via Structure-based Virtual Screening
<p>Data associated with the manuscript - Identification of Mitoxantrone as a Potent Inhibitor of Transcriptional Cyclin-Dependent Kinase 7 via Structure-based Virtual Screening </p>
Virtual screening data sets for fragmented interaction fingerprint
<p>Data sets containing docking poses, structure-activity relationship matrix (SARM) train-test splitting, and 2048 bits extended connectivity fingerprint (ECFP) descriptors for six biological targets. Poses were generated by employing molecular docking using Molecular Operating Environment (MOE) software. Details will be described in the original publication.</p>
Fluorescence-activated droplet sequencing (FAD-seq) directly provides sequences of screening hits in antibody discovery
<p>Contains source datas (e.g. uncropped gels, FASTQ nanopore sequences, numeric data) and the python scripts for Fluorescence-activated droplet sequencing (FAD-seq) publication</p>
PanDDA analysis of ligand screen against the NSP3 macrodomain of SARS-CoV-2: ligands from FrankenROCS fragment-linking pipeline and subsequent optimization of AVI-313
<p>This deposition contains the X-ray diffraction data used to run PanDDA in the ligand screen against the NSP3 macrodomain of SARS-CoV-2 described in Correy et al. 2024 (doi: https://doi.org/10.1101/2024.08.25.609621). Compounds were from fragment linking using FrankenROCS and subsequent optimization of AVI-313. </p> <p>frankenROCS_mac1.tar.gz contains structure factor intensities, PanDDA input/output and refined models/maps.</p> <p>frankenROCS_mac1_ligand-bound-states.tar.gz contains the ligand-bound states extracted from the multi-state PDB files.</p>
Verus: A Practical Foundation for Systems Verification -- Artifact -- Set 2 Screen Capture
<p>A screen capture of the experiment in Set 2 of the artifact for the SOSP24 conditionally accepted paper "Verus: A Practical Foundation for Systems Verification": the experiment was performed on an Amazon AWS c5.4xlarge machine running Windows.</p>
Supplemental Data- Figures and Tables-Soft Red Winter Wheat Elite Germplasm Screening and Evaluation for Strip Rust in the US Southeast Region
Open the record for dataset details and reuse information.
Phytochemical Screening and Microbial Activity of Essential Oil from Aerial Parts of Murraya paniculata (L.) Orange Jasmine
<p>Phytochemical Screening and Microbial Activity of Essential Oil from Aerial Parts of Murraya paniculata (L.) Orange Jasmine </p>
Dataset of Easy screen P300 speller brain–computer interface design
<p><span>This study tested an application on 30 subjects, comprising 11 healthy women and 19 healthy men. Brain signals were recorded using a Brain Products V-Amp 16 Channel EEG system, with electrodes positioned according to the International 10-20 system. The signals were filtered using a 1-12 Hz Butterworth band-pass and a 50 Hz Notch filter, then digitized at a sampling frequency of 2 kHz and transferred to a computer for further analysis.</span></p>
Supplemantal tables for "A Non-targeted Proteomics Newborn Screening Platform for Genetic Disorders".
<p>Table S1 (List of proteins identified in DBS samples analyzed in the study).</p> <p>The list includes identified proteins with peptide and protein false discovery rates < 1%. Proteins shown in black are those identified by unique peptide sequences that were clearly distinguishable from others. Proteins shown in blue represent grouped master proteins. Proteins shown in grey represent grouped proteins. A quantitative value of “0” indicates that the protein was detected, but did not reach a level sufficient for quantification.</p> <p>Table S2 (Proteins identified in DBS samples that are listed in OMIM)</p> <p>List of proteins identified in every healthy newborn sample that are included in the OMIM database. The list includes identified proteins with peptide and protein false discovery rates < 1%. AD, autosomal dominant; AR, autosomal recessive; ARLOF, autosomal recessive loss of function; XL, X-linked; IUIS2022, 2022 Classification of Human Inborn Errors of Immunity by the International Union of Immunological Societies Expert Committee.</p>
reseach data for the paper RAPID METHOD FOR SCREENING OF BOTH CALCIUM AND MAGNESIUM CHELATION WITH COMPARISON OF 21 KNOWN METAL CHELATORS
<p>research data usef for the paper RAPID METHOD FOR SCREENING OF BOTH CALCIUM AND MAGNESIUM CHELATION WITH COMPARISON OF 21 KNOWN METAL CHELATORS in Journal of Biological Inorganic Chemistry</p>
Phytochemical Screening and Microbial Activity of Essential Oil from Aerial Parts of Murraya paniculata (L.) Orange Jasmine
<p>Phytochemical Screening and Microbial Activity of Essential Oil from <br>Aerial Parts of Murraya paniculata (L.) Orange Jasmine </p>
Screening Process and Eligibility Decision for SR Anticancer Effects Curcumin, Shogaols, and Gingerols
<p>A dataset consisting of list of studies together with their inclusion/exclusion decision for</p> <p>a. Sheet 1: Excluded studies with reason(s) from electronic database search</p> <p>b. Sheet 2: Included studies from electronic database search</p> <p>c. Sheet 3: Decision on full-text screening</p> <p>d. Sheet 4: Decision on studies retrieved from other sources</p>
Data from: Transcriptome characterization and screening of molecular markers in ecologically important Himalayan species (Rhododendron arboreum)
Rhododendron arboreum is an ecologically prominent species, which also lends commercial and medicinal benefits in the form of palatable juices and useful herbal drugs. Local abundance and survival of the species under a highly fluctuating climate make it an ideal model for genetic structure and functional analysis. However, a lack of genomic data has hampered additional research. In the present study, cDNA libraries from floral and foliar tissues of the species were sequenced to provide a foundation for understanding the functional aspects of the genome and to construct an enriched repository that will promote genomics studies in the genera. Illumina's platform facilitated the generation of ∼100 million high-quality paired-end reads. De novo assembly, clustering, and filtering out of shorter transcripts predicted 113 167 non-redundant transcripts with an average length of 1164.6 bases. Of these, 71 961 transcripts were categorized based on functional annotations in the Gene Ontology database, whereby 5710 were grouped into 141 pathways and 23 746 encoded for different transcription factors. Transcriptome screening further identified 35 419 microsatellite regions, of which, 43 polymorphic loci were characterized on 30 genotypes. Seven hundred and nineteen transcripts had 811 high-quality single-nucleotide polymorphic variants with a minimum coverage of 10, a total score of 20, and SNP% of 50.
Data from: Screening test for neutralizing antibodies against yellow fever virus, based on a flavivirus pseudotype
Given the possibility of yellow fever virus reintroduction in epidemiologically receptive geographic areas, the risk of vaccine supply disruption is a serious issue. New strategies to reduce the doses of injected vaccines should be evaluated very carefully in terms of immunogenicity. The plaque reduction test for the determination of neutralizing antibodies (PRNT) is particularly time-consuming and requires the use of a confinement laboratory. We have developed a new test based on the use of a non-infectious pseudovirus (WN/YF17D). The presence of a reporter gene allows sensitive determination of neutralizing antibodies by flow cytometry. This WN/YF17D test was as sensitive as PRNT for the follow-up of yellow fever vaccinees. Both tests lacked specificity with sera from patients hospitalized for acute Dengue virus infection. Conversely, both assays were strictly negative in adults never exposed to flavivirus infection or vaccination, and in patients sampled some time after acute Dengue infection. This WN/YF17D test will be particularly useful for large epidemiological studies and for screening for neutralizing antibodies against yellow fever virus.
fasta for screening of lncRNA
<p>fasta for screening of lncRNA</p>
Data from: Wide range screening of algorithmic bias in word embedding models using large sentiment lexicons reveals underreported bias types
<p>Concerns about gender bias in word embedding models have captured substantial attention in the algorithmic bias research literature. Other bias types however have received lesser amounts of scrutiny. This work describes a large-scale analysis of sentiment associations in popular word embedding models along the lines of gender and ethnicity but also along the less frequently studied dimensions of socioeconomic status, age, physical appearance, sexual orientation, religious sentiment and political leanings. Consistent with previous scholarly literature, this work has found systemic bias against given names popular among African-Americans in most embedding models examined. Gender bias in embedding models however appears to be multifaceted and often reversed in polarity to what has been regularly reported. Interestingly, using the common operationalization of the term bias in the fairness literature, novel types of so far unreported bias types in word embedding models have also been identified. Specifically, the popular embedding models analyzed here display negative biases against middle and working-class socioeconomic status, male children, senior citizens, plain physical appearance and intellectual phenomena such as Islamic religious faith, non-religiosity and conservative political orientation. Reasons for the paradoxical underreporting of these bias types in the relevant literature are probably manifold but widely held blind spots when searching for algorithmic bias and a lack of widespread technical jargon to unambiguously describe a variety of algorithmic associations could conceivably be playing a role. The causal origins for the multiplicity of loaded associations attached to distinct demographic groups within embedding models are often unclear but the heterogeneity of said associations and their potential multifactorial roots raises doubts about the validity of grouping them all under the umbrella term bias. Richer and more fine-grained terminology as well as a more comprehensive exploration of the bias landscape could help the fairness epistemic community to characterize and neutralize algorithmic discrimination more efficiently.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.