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2,009 results for “Disruption”

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geo24/100

Intracellular Cryptococcus neoformans Disrupts the Transcriptome Profile of M1- and M2-Polarized Host Macrophages

GEO Series GSE150802. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2020View details →
geo24/100

Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity [Total RNA-seq, SLAM-seq]

GEO Series GSE153972. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenFeb 2021View details →
geo24/100

Disease-related AUTS2 disruption causes an imbalance of neuronal/glial lineage specification through the WNT/β-catenin pathway (scRNA-Seq).

GEO Series GSE255184. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2024View details →
geo24/100

Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human adult erythroid cells

GEO Series GSE121992. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2020View details →
geo24/100

Mechanistic models position ceritinib as a nuclear integrity disrupting therapy in pediatric liver tumors

GEO Series GSE306477. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo24/100

Mutations disrupting the kinase domain of IKKα lead to immunodeficiency and immune dysregulation in humans

GEO Series GSE267600. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2024View details →
geo24/100

Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors

GEO Series GSE107261. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2018View details →
geo24/100

Dibromoacetonitrile exposure induces neurobehavioral toxicity in adult zebrafish via disruption of multiple neural pathways

GEO Series GSE306907. Danio rerio. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo24/100

Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia [RNA-seq]

GEO Series GSE178306. Homo sapiens. 108 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2022View details →
geo24/100

[RNP-MaP] U1 snRNP regulates recruitment of early spliceosomal components by disrupting SRSF1-pre-mRNA interactions

GEO Series GSE188650. Human adenovirus 2. 6 samples. Type: Other.

openGEO-OpenJul 2022View details →
geo24/100

CRISPR modeling reveals transcriptional and functional changes associated with structural variant disruption to MEF2C and 5q14.3 topological organization in neuronal lineages

GEO Series GSE204778. Homo sapiens. 327 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.

openGEO-OpenJun 2022View details →
geo24/100

Floral transition in maize infected with Sporisorium reilianum disrupts compatibility with this biotrophic fungal pathogen

GEO Series GSE41916. Zea mays subsp. mays; Zea mays. 4 samples. Type: Expression profiling by array.

openGEO-OpenJan 2013View details →
geo24/100

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

GEO Series GSE24505. Homo sapiens. 757 samples. Type: Expression profiling by array; Methylation profiling by genome tiling array.

openGEO-OpenDec 2010View details →
geo24/100

Complex Balanced Translocation Disrupting TCF4 and Altering TCF4 Isoform Expression Segregates as Mild Autosomal Dominant Intellectual Disability

GEO Series GSE77742. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2016View details →
geo24/100

Human naïve-like T follicular regulatory cells are primed for differentiation into mature Tfr and disrupted during severe infections.

GEO Series GSE287876. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2025View details →
geo24/100

Inflammation of gill epithelia in fish causes increased permeation of polar organic chemicals from OSPW via disruption of tight junctions

GEO Series GSE182953. Oncorhynchus mykiss. 7 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2022View details →
geo24/100

Combination targeted therapy to disrupt aberrant oncogenic signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia

GEO Series GSE78692. Mus musculus. 54 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.

openGEO-OpenFeb 2017View details →
geo24/100

Disordered breathing in Pitt Hopkins syndrome involves disruption of parafacial respiratory neurons and aberrant expression of Nav1.8.

GEO Series GSE174417. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2021View details →
geo24/100

Obesity disrupts innate-adaptive immune network patterning in adipose tissue

GEO Series GSE198012. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2022View details →
geo24/100

RUNX1-EVI1 disrupts lineage determination and the cell cycle by interfering with RUNX1 and EVI1 driven gene regulatory networks

GEO Series GSE143460. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2020View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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