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6,383 results for “isolates”
Simulations from: Formation of the first three gravitational-wave observations through isolated binary evolution
<p>The results of all simulations shown and discussed in "<a href="https://www.nature.com/articles/ncomms14906">Formation of the first three gravitational-wave observations through isolated binary evolution</a>", published in Nature Communications, 8, 14906 (<a href="https://arxiv.org/abs/1704.01352">arXiv</a>).</p> <p>Contents:</p> <p>README<br> Z0_002_LVT151012_1475624202.dat<br> Z0_001_GW150914_1394278271.dat<br> Z0_002_allMergers.dat<br> Z0_001_GW151226_294773844.dat<br> Z0_002_alphalambda0_01_allMergers.dat<br> Z0_001_LVT151012_784739229.dat<br> Z0_002_fLBV_10_allMergers.dat<br> Z0_001_allMergers.dat<br> Z0_005_GW151226_1432529107.dat<br> Z0_001_alphalambda0_01_allMergers.dat<br> Z0_005_LVT151012_1051180640.dat<br> Z0_001_fLBV_10_allMergers.dat<br> Z0_005_allMergers.dat<br> Z0_002_GW151226_997696601.dat</p> <p>All simulations made using <a href="http://compas.science/">COMPAS</a></p>
Bioprospecting for bioactive peptide production by lactic acid bacteria isolated from fermented dairy food
<p>Table S1 of the review article "Bioprospecting for bioactive peptide production by lactic acid bacteria isolated from fermented dairy food"</p> <p>by Davide Tagliazucchi, Serena Martini and Lisa Solieri</p>
A bioactive compound isolated from Duku (Lansium domesticum Corr) fruit peels exhibits cytotoxicity against T47D cell line
<p><strong>Background: </strong>Breast cancer is a major health problem for women globally. Many attempts have been promoted to cure cancer by finding new anticancer medicines from natural resources. Despite the richness of biodiversity discovered, there are some natural resources that remain unexplored. Fruit peels of Duku (<em>Lansium domesticum</em> Corr.) are rich with compounds that may have the potential to be developed as anticancer drugs. This study aimed to isolate cytotoxic compounds from the fruit peels of <em>L. domesticum</em> and assess their cytotoxic nature against T47D cells.</p> <p><strong>Methods: </strong>Powdered peels were macerated with ethyl acetate and the filtrate was evaporated to give EtOAc extract A. Dried extract A was triturated with n-hexane to give n-hexane soluble fraction B and insoluble fraction C. The cytotoxic nature of these three samples were assessed using MTT assay using T47D cells and doxorubicin as a control</p> <p><strong>Results: </strong>Fraction C that showed the smallest IC<sub>50</sub> (25.56 + 0.64µg/mL) value compared to extract A and fraction BFraction C was further fractionated by vacuum liquid chromatography to give 6 subfractions. Subfraction 2 showed a single compound based on thin layer chromatography, and this compound was identified as Lamesticumin A on the basis of its spectroscopic data. Lamesticumin A demonstrated cytotoxic activity against T47D cell lines with an IC<sub>50</sub> value of 15.68 + 0.30µg/mL.</p>
Fig. 2. Invaginated protoscoleces isolated from a in Cystic echinococcosis in wild boars (Sus scrofa) from southern Italy: Epidemiological survey and molecular characterization
Fig. 2. Invaginated protoscoleces isolated from a fertile hydatid cyst.
Figure 1 in Size estimation of Synbranchus marmoratus and Synbranchus madeirae (Teleostei) based on isolated cranial and post-cranial bones
Figure 1. – Original drawing of Pseudocaranx chilensis from the description of Guichenot (1848).
Fig. 1 in The importance of isolated patches for maintaining local bird biodiversity and ecosystem function: a case study from the Pernambuco Center of Endemism, Northeast Brazil
Fig. 1. Rarefaction curve based at Mata do Cedro abundance and richness, state of Alagoas, Brazil.
Fig. 2 in The importance of isolated patches for maintaining local bird biodiversity and ecosystem function: a case study from the Pernambuco Center of Endemism, Northeast Brazil
Fig. 2. Functional dendrogram of species of birds found at Mata do Cedro, state of Alagoas, Brazil.
Fig. 1 in Co-infection of Echinococcus equinus and Echinococcus canadensis (G6/7) in a gray wolf in Turkey: First report and genetic variability of the isolates
Fig. 1. Stereomicroscopic view of adult parasites obtained from gray wolf's intestine.
FIGURE 7. Isolated chambers. 1 in Neoichnology of the eastern spadefoot toad, Scaphiopus holbrookii (Anura: Scaphiopodidae): criteria for recognizing anuran burrows in the fossil record
FIGURE 7. Isolated chambers. 1, Side view (SH20). 2, Frontal view (SH20). 3, Frontal view (SH67).
Figure 1 in Isolation and characterization of Klebsiella oxytoca from the rhizosphere of Lotus corniculatus and its biostimulating features
Figure 1. Pure colonies of the LCK121 strain from the rhizosphere of L. corniculatus.
Figure 4 in Evaluation of chitosan and silver nanoparticles Against isolated pathogens from Mulberry Silkworm, Bombyx mori L. (Lepidoptera: Bombycidae) under laboratory conditions
Figure 4. Transmissiоn electron microscоpy micrоgraph of silver nanoparticles.
Figure 3 in Evaluation of chitosan and silver nanoparticles Against isolated pathogens from Mulberry Silkworm, Bombyx mori L. (Lepidoptera: Bombycidae) under laboratory conditions
Figure 3. Final dispersion formed after reduction (A) silver and (B) chitosan.
Ndufs4 knockout mice with isolated complex I deficiency engage a futile adaptive brain response - supplementary data
<p>This study aims to provide insight into the Leigh Syndrome pathomechanism at the sub-brain level. To this end, a comparative proteome analysis was performed on various brain regions of 6 wildtype (WT) and 6 whole body (WB) Ndufs4-/- (WB-KO) mice over two experiments. Samples were collected at six weeks after birth (i.e. ~ one week prior to WB-KO death). For the first experiment samples were collected from a brain slice (BrSl), which contained (parts of) the CC, HC, hypothalamus, thalamus, caudate putamen, and olfactory areas. For the second experiment the analysed brain regions consisted of cerebellum (CB), cerebral cortex (CC), hippocampus (HC), inferior colliculust (IC), and superior colliculus (SC).</p>
Rapid Identification of Bacterial isolates Using Microfluidic Adaptive Channels and Multiplexed Fluorescence Microscopy
<p>Dataset for: Rapid Identification of Bacterial isolates Using Microfluidic Adaptive Channels and Multiplexed Fluorescence Microscopy</p> <p>doi: <a title="Link to landing page via DOI" href="https://doi.org/10.1039/D4LC00325J">10.1039/D4LC00325J</a></p>
Identification of microplastics isolated from Rusanda peloid (Serbia) with ATR-FTIR
<p>This dataset contains unprocessed FTIR spectra from the isolated microplastic candidates from the peloid sample from Rusanda Lake (Serbia). The spectra were processed with OpenSpecy 1.0 (https://openanalysis.org/openspecy/), an open-source spectral processing and matching tool (Cowger et al., 2021). The processed spectra are included as a separate folder in the dataset, together with top library matches for each spectrum. </p>
Incompatible interaction experiment with Aegilops cylindrica infected with Zymoseptoria tritici isolate Zt 244 (IPO323) - CSLM images and videos
<p>Microscopic images and videos from convocal laser scannning microscopy (CLSM) analysis using maximum projections of confocal z-stacks. Cell nuclei and plant tissue are visible in purple, fungal hyphae in green.</p>
Supplementary dataset to publication: Whole-genome sequencing of Streptococcus uberis isolated from cows with mastitis in Thuringia
<p><span><strong>Introduction</strong>.</span> <em><span>Streptococcus uberis</span></em> is a common cause of mastitis in cattle, leading to significant economic losses. The widespread use of antimicrobials has contributed to the emergence of resistance, which poses a severe challenge in controlling <em><span>S. uberis</span></em> infection.</p> <p><span><strong>Aim</strong>.</span> The objective of this study was to gain insights into the antimicrobial resistance (AMR) and epidemiological typing of <em><span>S. uberis</span></em> isolated from milk collected from bovine mastitis on dairy farms in Thuringia.</p> <p><span><strong>Methodology</strong>.</span> In this study, 84 <em><span>S. uberis</span></em> isolates were obtained from cattle with clinical mastitis in Thuringia, their phenotypic and genotypic AMR were analyzed and their phylogenetic relationship was explored using whole-genome sequencing.</p> <p><span><strong>Results</strong>.</span> Genetically heterogeneous strains were found on the farms, but clusters of highly similar strains also circulated within the same farms. All isolates were sensitive to ampicillin, penicillin, ceftiofur, and vancomycin. However, 42.9%, 42.9%, 22.6%, 19.0%, and 13.0% were resistant to tetracycline, doxycycline, clindamycin, pirlimycin, and erythromycin, respectively. Thirty-nine strains were phenotypically resistant to two or more tested antibiotics. We identified a plasmid associated with macrolide and lincosamide resistance in 12% of the strains.</p> <p><span><strong>Conclusion</strong>.</span> The emergence of <em><span>S. uberis</span></em> strains resistant to multiple antibiotics highlights the importance of <em><span>S. uberis</span></em> surveillance and the prudent use of antimicrobials.</p>
Data from: Integrating Bayesian genomic cline analyses and association mapping of morphological and ecological traits to dissect reproductive isolation and introgression in a Louisiana Iris hybrid zone
Hybrid zones provide unique opportunities to examine reproductive isolation and introgression in nature. We utilized 45,384 Single Nucleotide Polymorphism (SNP) loci to perform association mapping of 14 floral, vegetative, and ecological traits that differ between Iris hexagona and Iris fulva, and to investigate, using a Bayesian Genomic Cline (BGC) framework, patterns of genomic introgression in a large and phenotypically diverse hybrid zone in southern Louisiana. Many loci of small effect-size were consistently found to be associated with phenotypic variation across all traits, and several individual loci were revealed to influence phenotypic variation across multiple traits. Patterns of genomic introgression were quite heterogeneous throughout the Louisiana Iris genome, with I. hexagona alleles tending to be favored over those of I. fulva. Loci that were found to have exceptional patterns of introgression were also found to be significantly associated with phenotypic variation in a small number of morphological traits. However, this was the exception rather than the rule, as most loci that were associated with morphological trait variation were not significantly associated with excess ancestry. These findings provide insights into the complexity of the genomic architecture of phenotypic differences and are a first step towards identifying loci that are associated with both trait variation and reproductive isolation in nature.
A greenhouse experiment partially supports inferences of ecogeographic isolation from niche models of Clarkia sister species
<p><b>Premise: </b>Ecogeographic isolation, or geographic isolation caused by ecological divergence, is thought to be of primary importance in speciation, yet is difficult to demonstrate and quantify. To determine whether distributions are limited by divergent adaptation or historical contingency, the gold standard is to reciprocally transplant taxa between their geographic ranges. Alternatively, ecogeographic isolation is inferred from species distribution models and niche divergence tests based on widely available environmental and occurrence data.</p> <p><b>Methods: </b>We test for ecogeographic isolation between two sister species of California annual wildflowers, <i>Clarkia concinna</i> and <i>C. breweri</i>, with a hybrid approach. We use niche models to predict water availability as the major axis of ecological divergence and then test that with a greenhouse experiment. Specifically, we manipulate water availability in field soils for two populations of each species and predict higher fitness in conditions representing home habitats to those representing the environment of each's sister species.</p> <p><b>Key Results: </b>Water availability and soil representing <i>C. concinna</i> generally increased both species' fitness. Thus, water and soil may indeed limit <i>C. concinna</i> from colonizing the range of C. breweri, but not vice versa. We suggest that the competitive environment and pollinator availability, which are not directly captured with either approach, may be key biotic factors correlated with climate that contribute to unexplained ecogeographic isolation for <i>C. breweri</i>.</p> <p><b>Conclusions:</b> Ours is a valuable approach to assessing ecogeographic isolation, in that it balances feasibility with model validation, and our results have implications for species distribution modeling efforts geared towards predicting climate change responses.</p>
PKHhigh/CD133+/CD24− Renal Stem-Like Cells Isolated from Human Nephrospheres Exhibit In Vitro Multipotency.
<p>The mechanism upon which human kidneys undergo regeneration is debated, though different lineage-tracing mouse models have tried to explain the cellular types and the mechanisms involved. Different sources of human renal progenitors have been proposed, but it is difficult to argue whether these populations have the same capacities that have been described in mice. Using the nephrosphere (NS) model, we isolated the quiescent population of adult human renal stem-like PKH<sup>high</sup>/CD133+/CD24− cells (RSC). The aim of this study was to deepen the RSC in vitro multipotency capacity. RSC, not expressing endothelial markers, generated secondary nephrospheres containing CD31+/vWf+ cells and cytokeratin positive cells, indicating the coexistence of endothelial and epithelial commitment. RSC cultured on decellularized human renal scaffolds generated endothelial structures together with the proximal and distal tubular structures. CD31+ endothelial committed progenitors sorted from nephrospheres generated spheroids with endothelial-like sprouts in Matrigel. We also demonstrated the double commitment toward endothelial and epithelial lineages of single RSC. The ability of the plastic RSC population to recapitulate the development of tubular epithelial and endothelial renal lineages makes these cells a good tool for the creation of organoids with translational relevance for studying the parenchymal and endothelial cell interactions and developing new therapeutic strategies.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.