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3,514 results for “cell therapy”
Stem Cell Educator Therapy in Diabetes
ClinicalTrials.gov study NCT03390231. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Intermittent Therapy in Metastatic Renal Cell Carcinoma Patients Treated With Ipilimumab and Nivolumab
ClinicalTrials.gov study NCT03126331. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Immune Response on Neoadjuvant Therapy in Non-small-cell Lung Cancer (NSCLC)
ClinicalTrials.gov study NCT00406302. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Hematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A
ClinicalTrials.gov study NCT05265767. IPD Sharing: NO. Countries: 1. Publications: 1.
Humanized CAR-T Therapy for Treatment of B Cell Malignancy
ClinicalTrials.gov study NCT02782351. IPD Sharing: YES. Countries: 1. Publications: 4.
Natural Killer-cell Therapy for Acute Myeloid Leukemia
ClinicalTrials.gov study NCT04347616. IPD Sharing: NO. Countries: 1. Publications: 1.
High-throughput screen to identify and optimize NOT gate receptors for cell therapy
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Adiponectin stimulates exosome release to enhance mesenchymal stem cell driven therapy of heart failure in mice
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SARS-CoV-2 infected host cell proteomics reveal potential therapy targets
<p>Determination of the SARS-CoV-2 infection profile by translatome and proteome proteomics at different times after infection; identification of drugs inhibiting viral replication.</p>
Data from: Cell therapy for chronic TBI: interim analysis of the randomized, controlled, double-blind STEMTRA trial
<p><b>Objective:</b> To determine if chronic motor deficits secondary to traumatic brain injury (TBI) can be improved by implantation of allogeneic modified bone marrow-derived mesenchymal stromal/stem cells (SB623).</p> <p><b>Methods:</b> This 6-month interim analysis of the 1-year double-blind, randomized, surgical sham-controlled, Phase 2 STEMTRA trial (NCT02416492) evaluated safety and efficacy of the stereotactic intracranial implantation of SB623 in patients with stable chronic motor deficits secondary to TBI. Patients in this multi-center trial (N=63) underwent randomization in a 1:1:1:1 ratio to 2.5x10<sup>6</sup>, 5.0x10<sup>6</sup>, 10x10<sup>6</sup> SB623 cells or control. Safety was assessed in patients who underwent surgery (N=61), and efficacy in the modified intent-to-treat population of randomized patients who underwent surgery (N=61; SB623=46, control=15).</p> <p><b>Results:</b> The primary efficacy endpoint of significant improvement from baseline of Fugl-Meyer Motor Scale score at 6 months for SB623-treated patients was achieved. SB623-treated patients improved by (LS mean [SE]) +8.3 (1.4) versus +2.3 (2.5) for control at 6 months, the LS mean difference was 6.0 (95% CI: 0.3-11.8); P=0.040. Secondary efficacy endpoints improved from baseline, but were not statistically significant versus control at 6 months. There were no dose-limiting toxicities or deaths, and 100% of SB623-treated patients experienced treatment-emergent adverse events versus 93.3% of control patients (P=0.25).</p> <p><b>Conclusions:</b> SB623 cell implantation appeared to be safe and well tolerated, and patients implanted with SB623 experienced significant improvement from baseline motor status at 6 months compared to controls.</p> <p><b>Classification of Evidence:</b> This study provides Class I evidence that implantation of SB623 was well tolerated and associated with improvement in motor status.</p>
Raw - EBV-specific CD8 T lymphocytes and B cells during glatiramer acetate therapy in patients with MS
<p>Intracellular staining overnight</p>
Dataset for "Label-free enrichment of human pluripotent stem cell-derived early retinal progenitor cells for cell-based regenerative therapies"
<p>The raw dataset for "Label-free enrichment of human pluripotent stem cell-derived early retinal progenitor cells for cell-based regenerative therapies"</p> <p><span>DOI:</span><a href="https://doi.org/10.1016/j.stemcr.2023.12.001">https://doi.org/10.1016/j.stemcr.2023.12.001</a></p>
Fig. 3 in Microstructural Impact of Ischemia and Bone Marrow-Derived Cell Therapy Revealed With Diffusion Tensor Magnetic Resonance Imaging Tractography of the Heart In Vivo
Fig. 3. Amblyomma variegatum female before engorgement
CAR T-cell therapy
SciDraw upload
Data repository for the article: Fluorescence lifetime imaging unravels the pathway of glioma cell death upon hypericin-induced photodynamic therapy.
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Lung-MAP: Durvalumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers
ClinicalTrials.gov study NCT02766335. IPD Sharing: Not stated. Countries: 1. Publications: 0.
UARK 2013-05 A Study of Autologous Expanded Natural Killer Cell Therapy for Asymptomatic Multiple Myeloma
ClinicalTrials.gov study NCT01884688. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study to Identify Barriers to Cellular Therapies for People With Plasma Cell Disorders
ClinicalTrials.gov study NCT06126341. IPD Sharing: YES. Countries: 1. Publications: 0.
Low Level Laser Therapy for Radiation Induced Dermatitis in H & N Squamous Cell Carcinoma
ClinicalTrials.gov study NCT02384434. IPD Sharing: NO. Countries: 1. Publications: 0.
Pembro Plus CAR T-cell Therapy in R/R in PMBCL
ClinicalTrials.gov study NCT05934448. IPD Sharing: YES. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.