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6,699 results for “DEPRESSION”
Astrocytic PERK deficiency drives prefrontal circuit dysfunction and depressive-like behaviors
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Data from: Parasite-driven cascades or hydra effects: susceptibility and foraging depression shape parasite-host-resource interactions
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The effect of sertraline on depression and associations with persistent depression in survivors of HIV-related cryptococcal meningitis
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Data from: Predicting heterosis and inbreeding depression from population size and density to inform management efforts
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Data from: Virulent disease epidemics can increase host density by depressing foraging of hosts
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Patient-reported outcomes via electronic health record portal vs. telephone: process and retention data in a pilot trial of anxiety or depression symptoms in epilepsy
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Limited inbreeding avoidance at the gamete level despite inbreeding depression in Atlantic salmon (Salmo salar)
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Inbreeding depression contributes to the maintenance of habitat segregation between closely related monkeyflower species
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Data from: An experimental paradigm for triggering a depressive syndrome
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Data and code from: Parasite-mediated inbreeding depression in wild red deer
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Data from: Inbreeding depression across multiple life history traits in a long-lived mammal
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Data from: The conservation value of small population remnants: variability in inbreeding depression and heterosis of a perennial herb, the narrow-leaved purple coneflower (Echinacea angustifolia)
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PLATE VII. Species of the low elevation deserts in China (A-D) and northern Caspian Basin in Russia (E-F). (A) P. przewalskii-3; (B) habitat of A, Shapatou (foreground), Yellow River, Gobi Desert, Ningxia; (C) P. salenskyi-1; (D) habitat of C, near Jimsar, Junggar Depression, Xinjiang; (E) P. guttatus; and (F) habitat of E, west side of Caspian Sea in Dagestan. in A molecular phylogenetic hypothesis for the Asian agamid lizard genus Phrynocephalus reveals discrete biogeographic clades implicated by plate tectonics
PLATE VII. Species of the low elevation deserts in China (A-D) and northern Caspian Basin in Russia (E-F). (A) P. przewalskii-3; (B) habitat of A, Shapatou (foreground), Yellow River, Gobi Desert, Ningxia; (C) P. salenskyi-1; (D) habitat of C, near Jimsar, Junggar Depression, Xinjiang; (E) P. guttatus; and (F) habitat of E, west side of Caspian Sea in Dagestan.
Data from: Measuring the effect of environmental stress on inbreeding depression alone obscures the relative importance of inbreeding-stress interactions on overall fitness in Callosobruchus maculatus
<p>Environmental stress can have a profound effect on inbreeding depression. Quantifying this effect is of particular importance in threatened populations, which are often simultaneously subject to both inbreeding and environmental stress. But while the prevalence of inbreeding-stress interactions is well known, the importance and broader applicability of such interactions in conservation are not clearly understood. We used seed beetles, Callosobruchus maculatus, as a model system to quantify how environmental stressors (here host quality and temperature stress) interact with inbreeding as measured by changes in the magnitude of8inbreeding depression, δ, as well as the relative importance of inbreeding-stress interactions to overall fitness. We found that while both environmental stressors caused substantial inbreeding-stress interactions as measured by change in δ, the relative importance of these interactions to overall survival was modest. This suggests that assessing inbreeding-stress interactions within the framework of δ alone may give an inaccurate representation of the relevance of interactions to population persistence. Furthermore, we found that the effect of environmental stress on fitness, but not inbreeding depression, varied strongly among populations. These results suggest that the outcomes of inbreeding-stress interactions are not easily generalized, an important consideration in conservation settings.</p>
Dataset and analysis script for the manuscript "Status, rivalry and admiration-seeking in narcissism and depression: a behavioral study"
<p><em>Datasets and analysis script for the manuscript "Status, rivalry and admiration-seeking in narcissism and depression: a behavioral study".</em></p> <p><em>The attached R script begins with a read-me section with a short explanation of all variables present in the datasets. This information is also uploaded as a separate readMe in .txt format. Analyses are organized with respect to their order of appearance in the preprint (<a href="https://doi.org/10.31234/osf.io/mxve9">https://doi.org/10.31234/osf.io/mxve9</a>).</em></p> <p><em>The data is uploaded in two datasets: a long-format one (ds_pooled.csv) employed in the trial-by-trial regression models and a wide-format one for supplemental subject-level analyses (ds_pooled_wide.csv). The script contains code to further generate separate datasets for Samples 1 and 2 in both the long- and the wide-format. Please, refer to the manuscript for detailed information about how the data has been collected and analyzed.</em></p> <p><em>Note: The ds_items.zip file contains datasets with item scores of the included psychometric scales (trait-dominance, narcissism scales and depression scales). These files are only used in a short section of the script to compute reliability coefficients.</em></p>
Data from: Sibling competition does not magnify inbreeding depression in North American Arabidopsis lyrata
About half of all angiosperms have some form of molecular self-incompatibility to promote outcrossing. If self-incompatibility breaks down, inbreeding depression (δ) is the main barrier to the evolution of self-fertilization (selfing). If inbreeding depression is lower than 50% (δ<0.5), the inherent transmission advantage of selfers should drive the evolution of selfing. However, this does not always happen in practice. For example, despite frequent breakdowns of self-incompatibility in North American Arabidopsis lyrata, selfing has only evolved in few populations. This is surprising given that previous inbreeding-depression estimates were well below the 0.5 threshold. Here, we test whether this could be due to underestimation of true inbreeding depression in competition-free environments. Specifically, we tested whether direct competition between crossed and selfed siblings magnified inbreeding-depression estimates in A. lyrata. We found that this was neither the case for below-, nor for aboveground biomass. For reproductive traits, there was hardly any significant inbreeding depression regardless of competition. Combined with previous findings that drought stress and inducing defense also did not magnify inbreeding depression, our results suggest that the relatively low estimates of inbreeding depression for biomass are indeed realistic estimates of the true inbreeding depression in North American A. lyrata.
Depression and Stress among Bangladeshi Students during COVID-19 Lockdown
<p>This data was collected during COVID-19 pandemic (lockdown) from Bangladesh. The dataset contains social, financial, educational and other information including "Depression" and "Stress" (DASS-21 Scale) questions form tertiary level students. It was collected via google forms (e-questionnaire). </p>
Data from: Sleep, major depressive disorder and Alzheimer's disease: a Mendelian randomisation study
<div class="WordSection1"> <span><span>Objective</span></span> <p><span>To explore the causal relationships between sleep, major depressive disorder (MDD), and Alzheimer's disease (AD).</span></p> <span><span>Methods</span></span> <p><span>We conducted bi-directional two-sample Mendelian randomisation analyses. Genetic associations were obtained from the largest genome-wide association studies currently available in UK Biobank (N=446,118), the Psychiatric Genomics Consortium (N=18,759), and the International Genomics of Alzheimer's Project (N=63,926). We used the inverse variance weighted Mendelian randomisation method to estimate the causal effects, and the weighted median and MR-Egger for sensitivity analyses to test for pleiotropic effects. </span></p> <span><span>Results</span></span> <p><span>We found that higher risk of AD was significantly associated with being a "morning person" (odds ratio (OR)=1.01, P=0.001), shorter sleep duration (self-reported: β=-0.006, P=1.9×10<sup>-4</sup>; accelerometer-based: β=-0.015, P=6.9×10<sup>-5</sup>), less likely to report long sleep (β=-0.003, P=7.3×10<sup>-7</sup>), earlier timing of the least active 5 hours (β=-0.024, P=1.7×10<sup>-13</sup>), and a smaller number of sleep episodes (β=-0.025, P=5.7×10<sup>-14</sup>) after adjusting for multiple comparisons. We also found that higher risk of AD was associated with lower risk of insomnia (OR=0.99, P=7×10<sup>-13</sup>). However, we did not find evidence that these abnormal sleep patterns were causally related to AD or a significant causal relationship between MDD and risk of AD. </span></p> <span><span>Conclusion</span></span> <p><span>We found that AD may causally influence sleep patterns. However, we did not find evidence supporting a causal role of disturbed sleep patterns in AD or evidence for a causal relationship between MDD and AD risk.</span></p> </div> <p> </p>
ENDES2019 Dataset with interpretation on depressive symptomatology in Peruvian adults with HTA
<p>ENDES2019 Dataset with interpretation on depressive symptomatology in Peruvian adults with HTA</p>
Data from: How depressed? Estimates of inbreeding effects during seed development depend on reproductive conditions
Inbreeding depression can reduce the performance of offspring produced by mating between relatives, with consequences for population dynamics and sexual-system evolution. In flowering plants, inbreeding depression commonly acts most intensely during seed development. This predispersal component is typically estimated by comparing seed production following exclusive self- and cross-pollination, but such estimates are unbiased only if seed production is limited by ovule availability, rather than by pollen receipt or seed-development resources. To overcome this problem, we propose experimental and statistical methods based on a model of ovule fertilization and seed development that accounts for differential fertilization by self- and cross-pollen, limited ovule viability or receptivity, differential survival of self- and cross-zygotes and limited resource availability. Simulations illustrate that the proposed methods eliminate bias in estimated predispersal inbreeding depression caused by pollen limitation and can improve estimates under resource limitation. Application of these methods to two orchid species further demonstrates their utility in identifying and estimating diverse influences on reproductive performance under typical conditions. Although our theoretical results raise questions about the reported intensity of predispersal inbreeding depression, our proposed methods guard against bias while also providing insight into plant reproduction.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.