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2,098 results for “acting”
Human decisions about when to act originate within a basal forebrain-nigral circuit
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Data from: When to monitor and when to act: value of information theory for multiple management units and limited budgets
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Data for: Immigration counter-acts local micro-evolution of a major fitness component: migration-selection balance in free-living song sparrows
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Data from: A prezygotic transmission distorter acting equally in female and male zebra finches Taeniopygia guttata
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Data from: Enhancement of optical force acting on vesicles via the binding of gold nanoparticles
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Data from: Regulation of transposable elements: interplay between TE-encoded regulatory sequences and host-specific trans-acting factors in Drosophila melanogaster
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Data from: Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis
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ACT-America: L1 Raw, Uncalibrated In-Situ CO2, CO, and CH4 Mole Fractions from Towers
This dataset provides Level 1 (L1) in situ atmospheric carbon dioxide (CO2), carbon monoxide (CO), and methane (CH4) concentrations as measured on a network of instrumented communications towers across the central and eastern USA operated by the Atmospheric Carbon and Transport-America (ACT-America) project. There were 11 towers instrumented with cavity ring-down spectrometers (CRDS; Picarro Inc.) with measurements beginning in January 2015 and continuing to October 2019. The measurement period varied by tower site. The Picarro analyzers continuously measured total CH4, isotopic ratio of CH4, CO2, CO, and other greenhouse gas concentrations. Not all species were measured at all sites. Complete tower location, elevation, instrument height, and date/time information are also provided. Determination of greenhouse gas fluxes and uncertainty bounds is essential for the evaluation of the effectiveness of mitigation strategies. These L1 data are raw instrument outputs from the Picarro instruments. A Level 2 (L2) product derived from this L1 data is available and generally would be the preferred data for most use cases.
ACT-America: L1 Meteorological and Aircraft Navigational Data
This dataset provides aircraft navigational parameters and related meteorological data (often referred to as "housekeeping" data) in support of the research activities for the two aircrafts that flew for the NASA Atmospheric Carbon and Transport-America (ACT-America) project. ACT-America's mission spans five years and includes five 6-week intensive field campaigns covering all 4 seasons and 3 regions of the central and eastern United States. Two instrumented aircraft platforms, the NASA Langley Beechcraft B200 King Air and the NASA Goddard Space Flight Center's C-130H Hercules, were used to collect high-quality in situ measurements across a variety of continental surfaces and atmospheric conditions. During these flights, aircraft positional, meteorological, and environmental data are recorded by a variety of instruments. For this dataset, measurements include, but are not limited to: latitude, longitude, altitude, ground speed, air temperature, and wind speed and direction. These data are incorporated into related ACT-America flight-instrumented datasets to provide geotrajectory file information for position, attitude, and altitude awareness of instrumented sampling.
ACT-America: L2 In Situ CO2, CO, and CH4 Concentrations from Towers, Eastern USA
This dataset provides atmospheric carbon dioxide (CO2), carbon monoxide (CO), and methane (CH4) concentrations as measured on a network of instrumented communications towers operated by the Atmospheric Carbon and Transport-America (ACT-America) project. ACT-America's mission spans five years and includes five 6-week intensive field campaigns covering all 4 seasons and 3 regions of the central and eastern United States. Tower-based measurements began in early 2015 and are continuously collecting CO2, CO, and CH4 data to characterize ground-level (>100 m) carbon background conditions to support the periodic airborne measurement campaigns and transport modeling conducted by ACT-America. The towers are instrumented with infrared cavity ring-down spectrometer systems (CRDS; Picarro Inc.). Data are reported for the highest sampling port on each tower. The averaging interval standard deviation and uncertainty derived from periodic flask sample to in-situ measurement comparisons are provided. Complete tower location, elevation, instrument height, and date/time information are also provided.
ACT-America: L3 Merged In Situ Atmospheric Trace Gases and Flask Data, Eastern USA
This dataset provides merged data products acquired during flights over the central and eastern United States as part of the Atmospheric Carbon and Transport - America (ACT-America) project. Two aircraft platforms, the NASA Langley Beechcraft B200 King Air and the NASA Goddard Space Flight Center's C-130H Hercules, were used to collect high-quality in situ measurements across a variety of continental surfaces and atmospheric conditions. The merged data products are composed of continuous in situ measurements of atmospheric carbon dioxide (CO2), methane (CH4), carbon monoxide (CO), ozone (O3), and ethane (C2H6, B200 aircraft only) that were averaged to uniform intervals and merged with aircraft navigation and meteorological variables as well as trace gas concentrations from discrete flask samples collected with the Programmable Flask Package (PFP). These merged data products provide integrated measurements at intervals useful to the modeling community for studying the transport and fluxes of atmospheric carbon dioxide and methane across North America.
FLEXPART Influence Functions for ACT-America, 2016-2017
This dataset contains a set of Lagrangian particle dispersion simulations of carbon dioxide concentrations using the FLEXible PARTicle (FLEXPART) model. FLEXPART quantified the source-receptor relationships, so-called "influence functions", in a backward mode. The simulations were constructed for five Atmospheric Carbon and Transport America (ACT-America) deployments over the eastern U.S. that occurred in 2016-2019. Each receptor of the influence function is the 30-second or 10-minute interval along flight tracks, characterized by a box with boundaries between the maximum and minimum latitude/longitude as well as between the maximum and minimum altitudes during the interval. Each receptor box released 5,000 particles and simulated their transport and dispersion backward for 10 or 20 days. The simulations were driven by 27-km meteorology provided by the WRF-Chem simulation or by ERA-Interim data from the European Centre for Medium-Range Weather Forecasts (ECMWF). Background levels of carbon dioxide were obtained from CarbonTracker and OCO-2 v9 MIP. The data are provided in netCDF and FLEXPART binary formats.
ACT-America: L2 Remotely Sensed Column-avg CO2 by Airborne Lidar, Lite, Eastern USA
This dataset provides a direct subset (i.e., the Lite version) of the Level 2 (L2) remotely sensed column-average carbon dioxide (CO2) concentrations measured during airborne campaigns in Summer 2016, Winter 2017, Fall 2017, and Spring 2018 conducted over central and eastern regions of the U.S. for the Atmospheric Carbon and Transport (ACT-America) project. Column-average CO2 concentrations were measured at a 0.1-second frequency during flights of the C-130 Hercules aircraft at altitudes up to 8 km with a Multi-functional Fiber Laser Lidar (MFLL; Harris Corporation). The MFLL is a set of Continuous-Wave (CW) lidar instruments consisting of an intensity-modulated multi-frequency single-beam synchronous-detection Laser Absorption Spectrometer (LAS) operating at 1571 nm for measuring the column amount of CO2 number density and range between the aircraft and the surface or to cloud tops, and surface reflectance and a Pseudo-random Noise (PN) altimeter at 1596 nm for measuring the path length from the aircraft to the scattering surface and/or cloud tops. The MFLL was onboard all ACT-America seasonal campaigns, except Summer 2019. Complete aircraft flight information, interpolated to the 0.1-second column CO2 reporting frequency, is included, but not limited to, latitude, longitude, altitude, and attitude.
Non-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after exposure. Gene expression that is modified under these parameters were compared between Tgfb1 wild type and heterozygote littermates in order to determine which genes induced or repressed by radiation were mediated via Tgfb1 status. Differential gene expression was analyzed in Tgfb1 heterozygote and wild type littermate 4th mammary glands after whole body exposure to an acute dose of 10cGy ionizing radiation. Estrus cycle was normalized in all mice two days prior to irradiation by injection with an estrogen and progesterone mixture. It is widely believed that the carcinogenic action of ionizing radiation is due to targeted DNA damage and resulting mutations but there is also substantial evidence that non-targeted radiation effects alter epithelial phenotype and the stromal microenvironment. Activation of transforming growth factor beta 1 (TGFbeta) is a non-targeted radiation effect that mediates cell fate decisions following DNA damage and regulates microenvironment composition; it could either suppress or promote cancer. Gene expression profiling shown herein demonstrates that low dose radiation (10 cGy) elicits persistent changes in Tgfb1 wild type and heterozygote murine mammary gland that are highly modulated by TGFbeta. We asked if such non-targeted radiation effects contribute to carcinogenesis by using a novel radiation chimera model. Unirradiated Trp53 null mammary epithelium was transplanted to the mammary stroma of mice previously exposed to a single low (10 -100 cGy) radiation dose. By 300 days 100% of transplants in irradiated hosts at either 10 or 100 cGy had developed Trp53 null breast carcinomas compared to 54% in unirradiated hosts. Tumor growth rate was also increased by high but not low dose host irradiation. In contrast irradiation of Tgfb1 heterozygote mice prior to transplantation failed to decrease tumor latency or increase growth rate at any dose. Host irradiation significantly reduced the latency of invasive ductal carcinoma compared to spindle cell carcinoma as well as those tumors negative for smooth muscle actin in wild type but not Tgfb1 heterozygote mice. However irradiation of either host genotype significantly increased the frequency of estrogen receptor negative tumors. These data demonstrate two concepts critical to understanding radiation risks. First non-targeted radiation effects can significantly promote the frequency and alter the features of epithelial cancer. Second radiation-induced TGFbeta activity is a key mechanism of tumor promotion. Keywords: Differential gene expression after low dose irradiation Two genotypes: TGBbeta1 heterozygote and wildtype mouse mammary glands. Two time points post-10cGy-irradiation per genotype (1 week 4 weeks); control time point was 1 week post-sham-irradiation. Two or three replicates per time point.
ACT-America: L1 DAOD Measurements by Airborne CO2 Lidar, Eastern USA
This dataset provides Level 1 (L1) remotely sensed differential absorption optical depth (DAOD) measurements made through the Multi-Functional Fiber Laser Lidar (MFLL; Harris Corporation) during airborne campaigns in Summer 2016, Winter 2017, Fall 2017, and Spring 2018 conducted over central and eastern regions of the United States for the Atmospheric Carbon and Transport (ACT-America) project. DAOD were measured at 0.1 second frequency during flights of the C-130 Hercules aircraft at altitudes up to 8 km with MFLL. The MFLL is a set of Continuous-Wave (CW) lidar instruments consisting of an intensity modulated multi-frequency single-beam synchronous-detection Laser Absorption Spectrometer (LAS) operating at 1571 nm for measuring the column amount of CO2 number density and range between the aircraft and the surface or to cloud tops, and surface reflectance and a Pseudo-random Noise (PN) altimeter at 1596 nm for measuring the path length from the aircraft to the scattering surface and/or cloud tops. The MFLL was onboard all ACT-America seasonal campaigns, except Summer 2019. Complete aircraft flight information, interpolated to the 0.1 second column CO2 reporting frequency, are included, but not limited to, latitude, longitude, altitude, and attitude. Data users should note that a Level 2 (L2) MFLL data product is available (related dataset) that contains all data variables (plus the column-average CO2) included in this L1 MFLL data product but has undergone additional processing and calibrations and is recommended for most use cases.
ACT-America: L2 In Situ Atmospheric CO2, CO, CH4, and O3 Concentrations, Eastern USA
This dataset provides atmospheric carbon dioxide (CO2), carbon monoxide (CO), methane (CH4), water vapor (H2O), and ozone (O3) concentrations collected during airborne campaigns conducted by the Atmospheric Carbon and Transport-America (ACT-America) project. ACT-America's mission spanned 4 years and included five 6-week airborne campaigns covering all 4 seasons and 3 regions of the central and eastern United States. This dataset provides results from all five campaigns, including Summer 2016, Winter 2017, Fall 2017, Spring 2018, and Summer 2019. Two instrumented aircraft platforms, the NASA Langley Beechcraft B200 King Air and the NASA Goddard Space Flight Center's C-130H Hercules, were used to collect high-quality in situ measurements across a variety of continental surfaces and atmospheric conditions. CO2, CO, CH4, and H2O were collected with an infrared cavity ring-down spectrometer system (CRDS; Picarro Inc.). Ozone data were collected with a dual beam differential UV absorption ozone monitor (Model 205; 2B Technologies). Both aircraft hosted identical arrays of in situ sensors. Complete aircraft flight information including, but not limited to, latitude, longitude, altitude, and meteorological conditions are also provided.
ACT-America: L2 Remotely Sensed Column-average CO2 by Airborne Lidar, Eastern USA
This dataset provides Level 2 (L2) remotely sensed column-average carbon dioxide (CO2) concentrations measured during airborne campaigns in Summer 2016, Winter 2017, Fall 2017, and Spring 2018 conducted over central and eastern regions of the United States for the Atmospheric Carbon and Transport (ACT-America) project. Column-average CO2 concentrations were measured at 0.1 second frequency during flights of the C-130 Hercules aircraft at altitudes up to 8 km with a Multi-functional Fiber Laser Lidar (MFLL; Harris Corporation). The MFLL is a set of Continuous-Wave (CW) lidar instruments consisting of an intensity modulated multi-frequency single-beam synchronous-detection Laser Absorption Spectrometer (LAS) operating at 1571 nm for measuring the column amount of CO2 number density and range between the aircraft and the surface or to cloud tops, and surface reflectance and a Pseudo-random Noise (PN) altimeter at 1596 nm for measuring the path length from the aircraft to the scattering surface and/or cloud tops. The MFLL was onboard all ACT-America seasonal campaigns, except Summer 2019. Complete aircraft flight information, interpolated to the 0.1 second column CO2 reporting frequency, are included, but not limited to, latitude, longitude, altitude, and attitude. Processing for this Level 2 (L2) product included additional processing and calibration procedures described in this document as applied to retrieval of column CO2 from L1 MFLL data. Data users should use this L2 data unless different CO2 retrieval criteria are preferred.
ACT-America: Profile-based Planetary Boundary Layer Heights, Eastern USA
This dataset provides profile-based estimates of the height to the top of the planetary boundary layer (PBL), also known as the atmospheric boundary layer (ABL), in meters above mean sea level estimated from meteorological measurements acquired during ascending or descending vertical profile flight segments during NASA's Atmospheric Carbon and Transport - America (ACT-America) airborne campaign. ACT-America flights sampled the atmosphere over the central and eastern United States seasonally from 2016 - 2019. Two aircraft platforms, the NASA Langley Beechcraft B-200 King Air and the NASA Goddard Space Flight Center's C-130 Hercules, were used to collect high-quality in situ measurements across a variety of continental surfaces and atmospheric conditions.
ACT-America: Gridded Ensembles of Surface Biogenic Carbon Fluxes, 2003-2019
This data set provides gridded, model-derived gross primary productivity (GPP), ecosystem respiration (RECO), and net ecosystem exchange (NEE) of CO2 biogenic fluxes and their uncertainties at monthly and 3-hourly time scales over 2003-2019 on a 463-m spatial resolution grid for the conterminous United States (CONUS) and on both 5-km and half-degree spatial resolution grids for North America (NA). The biogeochemical model Carnegie Ames Stanford Approach (CASA) was used.
ACT-America: L2 In Situ Atmospheric Gas Concentrations from Flasks, Eastern USA
This dataset provides atmospheric carbon dioxide (CO2), methane (CH4), carbon monoxide (CO), molecular hydrogen (H2), nitrous oxide (N2O), sulfur hexafluoride (SF6), and other trace gas mole fractions (i.e., concentrations) from airborne campaigns over North America for the NASA Atmospheric Carbon and Transport - America (ACT-America) project. ACT-America's mission spanned five years and included five six-week field campaigns covering all four seasons and three regions of the central and eastern United States. Two instrumented aircraft platforms, the NASA Langley Beechcraft B-200 King Air and the NASA Goddard Space Flight Center's C-130 Hercules, were used to collect high-quality in situ measurements across a variety of continental surfaces and atmospheric conditions. The data were derived from laboratory measurements of whole air samples collected by Programmable Flask Packages (PFP) onboard the two ACT-America aircraft. Approximately 10 - 12 discrete flask samples were captured during each of the 195 flights. This dataset provides results from all five campaigns, including Summer 2016, Winter 2017, Fall 2017, Spring 2018, and Summer 2019.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.