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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Filovirus Infection Disrupts Epithelial Barrier Function and Ion Transport in Human iPSC-Derived Gut Organoids
GEO Series GSE298600. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Adolescent circadian rhythm disruption increases reward and risk-taking
GEO Series GSE282275. Mus musculus. 62 samples. Type: Expression profiling by high throughput sequencing.
Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer
GEO Series GSE267426. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β-cell function [scATAC-seq]
GEO Series GSE182937. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting CD206+ macrophages disrupts the establishment of a key anti-tumor immune axis [Bulk RNA-seq]
GEO Series GSE281471. Homo sapiens. 243 samples. Type: Expression profiling by high throughput sequencing.
Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modifications
GEO Series GSE278354. Mus musculus; Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing.
Genetic alterations of SENP6 disrupt DNA repair and proteostasis conferring sensitivity to proteasome inhibition in multiple myeloma
GEO Series GSE303255. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Genetic disruption of COX-1 inhibits multiple oncogenic pathways
GEO Series GSE66173. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Combined epigenetic therapy with FACT and BET inhibitors remodels chromatin and disrupts oncogenic transcription in Diffuse Midline Glioma [Xenium]
GEO Series GSE299434. Mus musculus. 4 samples. Type: Other.
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia
GEO Series GSE101791. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
KDM4 inhibition disrupts the core regulatory transcriptional circuitry in MYCN-driven neuroblastoma [Cut&Tag]
GEO Series GSE164454. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disruption of glucagon receptor increase α-cell glucagon expression and secretion beyond hyperplasia in zebrafish
GEO Series GSE179894. Danio rerio. 2 samples. Type: Expression profiling by high throughput sequencing.
High-throughput splicing assays identify missense and silent splice-disruptive POU1F1 variants underlying pituitary hormone deficiency
GEO Series GSE172504. Homo sapiens; Chlorocebus aethiops. 18 samples. Type: Other.
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy
GEO Series GSE97806. Mus musculus; Homo sapiens. 25 samples. Type: Expression profiling by high throughput sequencing.
Nuclear Protein Aggregates Disrupt RNA Processing and Alter Biomechanics in a Muscle Cell Model of OPMD
GEO Series GSE277571. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
A MYT1L Syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation [RNA-Seq]
GEO Series GSE173926. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
Pharmacological disruption of the Notch transcription factor complex
GEO Series GSE148228. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA]
GEO Series GSE81498. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
SETBP1 variants outside the degron disrupt DNA-binding, transcription and neuronal differentiation capacity to cause a heterogeneous neurodevelopmental disorder [fibroblast]
GEO Series GSE301238. Homo sapiens. 69 samples. Type: Expression profiling by high throughput sequencing.
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration [BLISS]
GEO Series GSE227438. Mus musculus. 6 samples. Type: Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.