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21,320 results for “Transcription”
Transcriptional analysis of spleens from mice preserved with the Rapid Freeze hardware
Data from the NASA Rodent Research-1 (RR-1) mission showed that gene-expression levels in mouse livers are different depending on what tissue preservation protocol is used and that slow freezing is not an effective method for preserving signals in gene-expression data. In response to these and other observations the Rapid Freeze hardware was built for use on the International Space Station. The Rapid Freeze hardware freezes mouse tissues (Glovebox freezer) and whole carcasses (Cryochiller) at rates closely mimicking those attained with immersion in liquid nitrogen. Because this hardware will be used extensively on future rodent research missions it is crucial to understand whether or not it preserves signals in gene expression data in order to maximize the value of these rare and expensive spaceflight experiments. Therefore this study was designed with three goals: 1) To evaluate the temperature profile of the Cryochiller and Glovebox freezer cartridges (Rapid Freeze hardware) over time during mock on-orbit procedures; 2) To determine the freezing profiles of tissues and carcasses using Rapid Freeze hardware at both optimal and sub-optimal temperatures (to mimic on-orbit operations) compared with those frozen in liquid nitrogen (the laboratory gold standard) or frozen in at -80 C (the current standard method); 3) To identify gene expression changes in a) tissues that were frozen via the Glovebox freezer and b) tissues dissected from whole or partial carcasses that were frozen via the Cryochiller versus tissues that were frozen via control methods (liquid nitrogen or -80C slow freeze) to assess how the Rapid Freeze hardware compares with laboratory gold standard practices and our current standard methods.
Transcriptional Profiles of Pulmonary Artery Endothelial Cells in Pulmonary Hypertension
GEO Series GSE243193. Homo sapiens. 55 samples. Type: Expression profiling by high throughput sequencing.
Global transcript analysis of quantitative trait loci (QTL) associated with meat tenderness in pigs
GEO Series GSE75707. Sus scrofa. 32 samples. Type: Expression profiling by high throughput sequencing.
Alteration of CTCF associated chromatin neighborhood inhibits TAL1-driven oncogenic transcription program and leukemogenesis
GEO Series GSE135320. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
SS18::SSX redistributes BAF chromatin remodelers selectively to activate and repress transcription [ChIP-Seq, Hi-ChIP]
GEO Series GSE269770. Mus musculus. 71 samples. Type: Other.
The transcription factor Gli3 promotes B cell development in the fetal liver through repression of Shh
GEO Series GSE81467. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional atlas of the cytokine drivers and cellular contributors mediating enhanced SARS-CoV-2 lung pathology in hamsters after non-protective immunization
GEO Series GSE195939. Mesocricetus auratus. 16 samples. Type: Expression profiling by high throughput sequencing.
Single-cell transcriptional analysis of human pluripotent stem cell-derived heart epicardium-myocardium organoids uncover principals of human epicardial-derived cells specification and coronary vascul
GEO Series GSE309829. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Generation of transcriptional regulatory network of Lgr5+ small and large intestinal stem cells from mouse [scRNA-seq]
GEO Series GSE196915. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Tbx5-dependent transcripts of the embryonic left ventricle
GEO Series GSE125823. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Mycobacterium tuberculosis transcriptional response to Pretomanid
GEO Series GSE165671. Mycobacterium tuberculosis. 27 samples. Type: Expression profiling by high throughput sequencing.
Molecular basis of NFIB-Mediated Regulation of Oncogenic Transcription
GEO Series GSE304865. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional Reprogramming during Floral Fate Acquisition III
GEO Series GSE205298. Arabidopsis thaliana. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional competence defines the heterochromatin nucleating potential of isolated MSR copies. [RNA-Seq]
GEO Series GSE299895. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Global transcriptional profiles of primary and secondary cellular senescence in vivo by oncogene-induced senescence (OIS) and stress-induced senescence (SIS) [Bulk RNA-seq]
GEO Series GSE242704. Mus musculus. 70 samples. Type: Expression profiling by high throughput sequencing.
High-throughput discovery of post-transcriptional cis-regulatory elements
GEO Series GSE75161. Homo sapiens. 4 samples. Type: Other; Non-coding RNA profiling by high throughput sequencing.
The C-terminal region of Xpc is dispensable for the transcriptional activity of Oct3/4 in mouse embryonic stem cells
GEO Series GSE69640. Mus musculus. 9 samples. Type: Expression profiling by array.
Tracking transcript abundance changes of D. vulgaris co-cultures with M. maripaludis in fluctuating resource environment
GEO Series GSE79022. Nitratidesulfovibrio vulgaris str. Hildenborough. 29 samples. Type: Expression profiling by high throughput sequencing.
A Unified Framework for Systematic Identification of Post-Transcriptional Regulatory Modules [TAF_15_KO_splicing ]
GEO Series GSE274252. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Integrated transcriptional and phenotypic analysis of peripheral blood to capture the immunomodulating properties of pazopanib in rena; cell carcinoma patients
GEO Series GSE146163. Homo sapiens. 23 samples. Type: Expression profiling by array.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.