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5,061 results for “access”
Systematic review of marine environmental DNA metabarcoding studies: Toward best practices for data usability and accessibility
<p>The emerging field of environmental DNA (eDNA) research lacks universal guidelines for ensuring data produced are FAIR–findable, accessible, interoperable, and reusable–despite growing awareness of the importance of such practices. In order to better understand these data usability challenges, we systematically reviewed 60 peer-reviewed articles conducting a specific subset of eDNA research: metabarcoding studies in marine environments. For each article, we characterized approximately 90 features across several categories: general article attributes and topics, methodological choices, types of metadata included, and availability and storage of sequence data. Analyzing these characteristics, we identified several barriers to data accessibility, including a lack of common context and vocabulary across the articles, missing metadata, supplementary information limitations, and a concentration of both sample collection and analysis in the United States. While some of these barriers require significant effort to address, we also found many instances where small choices made by authors and journals could have an outsized influence on the discoverability and reusability of data. Promisingly, articles also showed consistency and creativity in data storage choices as well as a strong trend toward open access publishing. Our analysis underscores the need to think critically about data accessibility and usability as marine eDNA metabarcoding studies, and eDNA projects more broadly, continue to proliferate.</p>
Genova - Urban green space accessibility and distribution
<p>Results of the evaluation of urban green space accessibility and distribution in Genova.</p>
Eindhoven - Urban green space accessibility and distribution
<p>Results of the evaluation of urban green space accessibility and distribution in Eindhoven.</p>
Accessible light-controlled knockdown of cell-free protein synthesis using phosphorothioate-caged antisense oligonucleotides (Raw data)
<p>Raw data for publication "Accessible light-controlled knockdown of cell-free protein synthesis using phosphorothioate-caged antisense oligonucleotides" (https://chemrxiv.org/engage/chemrxiv/article-details/6389f2dbe6f9a1754b2876d7)</p>
Proteome-wide structure-based accessibility analysis of ligandable and detectable cysteines in chemoproteomic datasets
<p>Covalent drug discovery, in particular targeting reactive cysteines, has undergone a resurgence over the past two decades, demonstrated by recent clinical successes of covalent inhibitors for high-priority cancer targets. Reactive cysteine profiling, first pioneered by the Cravatt lab, has emerged in parallel as a powerful approach for proteome-wide on- and off-target profiling. Thus far however, structural analysis of liganded cysteines has been restricted to experimentally determined protein structures. We combined AlphaFold-predicted amino acid side chain accessibilities for >95% of the human proteome with a meta-analysis of thirteen public cysteine profiling datasets, totalling 40,070 unique cysteine residues, revealing accessibility biases in sampled cysteines primarily dictated by warhead chemistry. Analysis of >3.5 million cysteine-fragment interactions further suggests that exposed cysteine residues are preferentially targeted by elaborated fragments and drug-like compounds. We finally propose a framework for benchmarking coverage of ligandable cysteines in future cysteine profiling approaches, considering both selectivity for high-priority residues and quantitative depth. All analysis and produced resources (freely available at <a href="http://www.github.com/TateLab">www.github.com/TateLab</a>) are readily extendable to reactive amino acids beyond cysteine, and related questions in chemical biology.</p>
Open access and international co-authorship: a longitudinal study of the United Arab Emirates research output
<p>Enriched data from Scopus used for the article: Open access and international co-authorship: a longitudinal study of the United Arab Emirates research output</p>
Access to Opioid Agonist Treatment during COVID-19 Project
<p>Data on methadone clinics and travel times used for research on opioid treatment access during COVID-19 public transport disruptions. For data on 2020 neighbourhood-level ambulance calls in Toronto, please contact "edau@toronto.ca".</p>
Data for: "Access to global reserves determines vulnerability to supply disruption of Ukrainian wheat"
<p>Repository with dataset and R scripts accompanying the paper "Access to global reserves determines vulnerability to supply disruption of Ukrainian wheat" by Bertassello, Muller and Winters.</p>
Deciphering the structural dynamics in molten salt-promoted MgO-based CO2 sorbents and their role in the CO2 uptake. Open data access
<p><strong>Open data for publication "Deciphering the structural dynamics in molten salt-promoted MgO-based CO<sub>2</sub> sorbents and their role in the CO<sub>2</sub> uptake" </strong></p>
Code & Data for Moving the 15-minute city beyond the urban core: the role of accessibility and public transport in The Netherlands
<p>Code & Data for Moving the 15-minute city beyond the urban core: the role of accessibility and public transport in The Netherlands</p>
Structures and data for minimalistic models of cage-like molecules in "Systematic exploration of accessible topologies of cage molecules via minimalistic models"
<p>Archives of .csv files containing data of lowest energy conformers for all cage configurations tested and associated .mol files. </p><p> </p><p>For paper: Systematic exploration of accessible topologies of cage molecules via minimalistic models with DOI: <a href="https://doi.org/10.1039/D3SC03991A">10.1039/D3SC03991A</a> </p>
Fig. 4 in Glandular trichome-derived sesquiterpenes of wild tomato accessions (Solanum habrochaites) affect aphid performance and feeding behavior
Fig. 4. Effect of pure β-caryophyllene and α-humulene on M. euphorbiae feeding performance (A–C) and choice behavior (D). Different amounts of a mix of pure β-caryophyllene and α-humulene (3:1 ratio) were added to the feeding diet. The data in (A), (B), and (C) show the comparison of Kaplan-Meier survival curves (logrank test, α =0.05), gel saliva density (Tukey's HSD, α =0.05), and number of honeydew drops (ANOVA, α = 0.05), respectively, upon addition of different amounts of pure sesquiterpenes to the artificial diet. The data in (D) represent the behavioral responses of aphid alatae to odors from leaves of c.v. M82 alone (right bars) or from leaves of c.v. M82 leaves in combination with different amounts of a mix of pure β-caryophyllene and α-humulene (left bars) (Chi-square goodness of fit; *, P <0.05; **, P <0.01).
Fig. 5 in Glandular trichome-derived sesquiterpenes of wild tomato accessions (Solanum habrochaites) affect aphid performance and feeding behavior
Fig. 5. α-Santalene and α-bergamotene producing tomato introgression line affects performance, feeding and choice behavior of M. euphorbiae. (A) Performance of M. euphorbiae apterae arrested on the leaf surface of S. lycopersicum LA4024, S. habrochaites LA1777, and the introgression lines LA3935, LA3934, LA3936, and LA3937. Values for longevity and fecundity are presented as mean ± SE and compared by Tukey's HSD test (α =0.05). (B) Kaplan-Meier estimates of survivorship of M. euphorbiae apterae feeding on artificial diets containing leaf dip extracts of S. lycopersicum LA4024, S. habrochaites LA1777, and the introgression line LA3935 (logrank test, α = 0.05). (C) and (D) Box plots represent means ± SE of gel saliva density (cm 2) and number of honeydew drops, respectively. Tukey's HSD tests (α = 0.05) are used for post-hoc analysis. (E) Choice of M. euphorbiae alatae between odors from LA4024 leaves alone (left bars) and from LA4024 leaves with added leaf dip extracts (100 and 300 μL) from the introgression line LA3935 or S. habrochaites LA1777 (right bars) (Chi-square goodness of fit; *, P <0.05; **, P <0.01).
Fig. 3 in Glandular trichome-derived sesquiterpenes of wild tomato accessions (Solanum habrochaites) affect aphid performance and feeding behavior
Fig. 3. Choice behavior of M. euphorbiae alatae in an open Y-track olfactometer. (A) Choice of aphids between air and odors from leaves of different S. lycopersicum cultivars or S. habrochaites accessions. (B) Choice of aphids between odors from leaves of c.v. M82 and different S. habrochaites accessions. (C) Choice of aphids between odors from leaves of c.v. M82 leaves alone (left bars) and from leaves of c.v. M82 leaves with added S. habrochaites leaf dip extracts (right bars). Asterisks following each pair of bars indicates significant differences according to Chi-square goodness of fit (⋅, P <0.07; *, P <0.05; **, P <0.01).
Fig. 2 in Glandular trichome-derived sesquiterpenes of wild tomato accessions (Solanum habrochaites) affect aphid performance and feeding behavior
Fig. 2. Feeding performance of M. euphorbiae apterae on artificial diets containing leaf dip extracts of S. lycopersicum c.v. M82 and different S. habrochaites accessions (MTBE solvent control). (A) Kaplan-Meier estimates of survivorship and analysis of log-rank test (α =0.05). (B) Box and violin plots represent mean ± SE of gel saliva density (cm 2) and the probability density, respectively. (C) Number of honeydew drops accumulated in the feeding chambers. Asterisks in (B) and (C) represent significant differences between diets with leaf dip extracts and control based on Dunnett's test (⋅, P <0.08; *, P <0.05; **, P <0.01; ***, P <0.001).
Fig. 1 in Glandular trichome-derived sesquiterpenes of wild tomato accessions (Solanum habrochaites) affect aphid performance and feeding behavior
Fig. 1. Longevity (A) and fecundity (B) of M. euphorbiae apterae arrested on the leaf surface of two S. lycopersicum cultivars and different S. habrochaites accessions. Solanum habrochaites accessions represent five chemotypes characterized by the production of different sesquiterpenes in their glandular trichomes. Values for longevity and fecundity are presented as mean ± SE. Different letters indicate that logarithmic values were significantly different (Tukey's HSD test, α = 0.05).
Dataset: Context-based Access Control and Attack Modelling and Analysis
<p>This repository contains the dataset for my PhD thesis "Context-based Access Control and Attack Modelling and Analysis". For the description, please look at the included README.md for further description.</p>
Ditte Laursen: Developing a legal agreement for research-access to a web archive
<p>Ditte Laursen: Developing a legal agreement for research-access to a web archive</p> <p>WARcnet Luxembourg meeting Thursday 5 November 2020</p>
Genome assemblies for Hadza Prevotella Require Diet-derived Microbiota Accessible Carbohydrates to Persist in mice.
<p>Genome scaffolds, annotations, and CAZy prediction for Gellman et al., 2023.</p>
Open access journals in the field of library and information sciences (LIS)
<p>List of foreign open access journals in the field of LIS is presented</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.