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zenodo28/100

Figure 3 from: Li Y, Liu C, Lin L, Li Y, Xiao J, Loh K-H (2020) Pleistocene isolation caused by sea-level fluctuations shaped genetic characterization of Pampus minor over a large-scale geographical distribution. ZooKeys 969: 137-154. https://doi.org/10.3897/zookeys.969.52069

Figure 3 NJ tree and distribution of Cytb haplotypes among populations for P. minor. Bootstrap supports of > 50 in 1000 replicates are shown.

opencc-by-4.0Sep 2020View details →
zenodo28/100

A Large Scale Study On the Effectiveness of Manual and Automatic Unit Test Generation

<p>Recently, an increasingly large amount of effort has been devoted to implementing tools to generate unit test suites automatically. Previous studies have investigated the effectiveness of these tools by comparing automatically generated test suites (ATSs) to manually written test suites (MTSs). Most of these studies report that ATSs can achieve higher code coverage, or even mutation coverage, than MTSs, particularly when suites are generated from defective code. However, these studies usually consider a limited amount of classes or subject programs, while the adoption of such tools in the industry is still low. This work aims to compare the effectiveness of ATSs and MTSs when applied as regression test suites. We conduct an empirical study, using ten programs (1368 classes), written in Java, that already have MTSs and apply two sophisticated tools that automatically generate test cases: Randoop and EvoSuite. To evaluate the test suites&rsquo; effectiveness, we use line and mutation coverage. Our results indicate that MTSs are, in general, more effective than ATSs regarding the investigated metrics. Moreover, the number of generated test cases may not indicate test suites&rsquo; effectiveness. Furthermore, there are situations when ATSs are more effective, and even when ATSs and MTSs can be complementary.</p>

opencc-by-4.0Oct 2020View details →
dryad28/100

Data from: Latitudinal variation of arrival and breeding phenology of the pied flycatcher Ficedula hypoleuca using large-scale citizen science data.

<p class="gmail-">Many species have advanced the timing of annual reproductive cycles in response to climatic warming, sometimes leading to asynchrony between trophic levels, with negative population consequences. Long-distance migratory birds, reliant on short seasonal food pulses for breeding, are considered particularly susceptible to such disjunction because late arrival may preclude optimal timing of egg-laying. It is unknown whether the relative timing of arrival and egg-laying is sufficiently plastic, in time and space, to enable an adaptive response when arrival times change relative to local food resources. We used citizen science data, describing pied flycatcher <i>Ficedula hypoleuca</i> arrival and egg-laying dates, to explore temporal (2013-2016) and spatial (across Great Britain) variation in the phenology of arrival, laying and their difference. To assess the long-term trend in arrival and laying at a single location, we used data from a long-term field study. The arrival-laying interval was consistently shorter in the north, driven by the contrast between spatial variation in arrival date and spatial invariance in laying date. To understand whether a short arrival-laying interval may have consequences for productivity, we assessed the association between this interval and clutch size. We found no statistically significant correlation between these two variables. To examine long-term changes in arrival and laying dates, we focussed on a single location in southwestern England. Both dates of first male arrival and first egg laid in a season advanced since 1986, with no evidence of interval shortening. Together, our results demonstrate spatial and annual variation in the arrival-laying interval, with no detected effect on fecundity. Thus, the interval from arrival to laying is likely dictated by spatially and temporally varying local conditions, suggesting these migrant birds may have the ability to adapt this interval to align with local conditions and mitigate potential mismatch impacts.</p>

opencc-zeroNov 2020View details →
dryad28/100

Data from: Altitude shapes the environmental drivers of large-scale variation in abundance of a widespread mammal species

<p>Habitat quality and heterogeneity directly influence the distribution and abundance of organisms at different spatial scales. Determining the main environmental factors driving the variation in species abundance is crucial to understand the underlying ecological processes and this is especially important for widely distributed species living in contrasting environments. However, the responses to environmental variation are usually described at relatively small spatial scales. Here, we studied the variation in abundance of a widely distributed mustelid, the European badger (<i>Meles meles</i>), across France.<b> </b>We used (1) direct detections of 9,439 dead and living badgers, from 2006 to 2009, to estimate badger relative abundance in 703 small agricultural regions of metropolitan France and (2) a Bayesian modelling approach to identify the main environmental determinants influencing badger abundance.<b> </b>Despite a continuous distribution of badger in France, we found large variation in badger abundance between regions, explained by environmental factors. Among a set of 13 environmental variables, we demonstrated that badger abundance in lowlands (&lt; 400 m a.s.l.) was mostly driven by biotic factors such as potential food resources (earthworm abundance and fruits crops) and forest fragmentation. Conversely, in mountainous areas, abiotic factors (i.e. soil texture and climate) drove the variation in badger relative abundance.<b> </b>These results underline the importance of mapping the abundance of wildlife species based on environmental suitability, and highlight the complexity of drivers influencing species abundance at such large spatial scales. Altitude shaped the environmental drivers (biotic <i>vs.</i> abiotic) that most influenced relative abundance of a widespread species. In the case of badger, such abundance maps are crucial to identify critical areas for species management as this mustelid is a main wild vector of bovine tuberculosis in several countries.</p>

opencc-zeroNov 2020View details →
zenodo28/100

Figure 8 from: Avila-Poveda OH (2020) Large-scale project 'Chiton of the Mexican Tropical Pacific': Chiton articulatus (Mollusca: Polyplacophora). Research Ideas and Outcomes 6: e60446. https://doi.org/10.3897/rio.6.e60446

Figure 8 Schematic diagram of the methodological process through which the chitons will pass to fulfil each of the proposed themes.

opencc-by-4.0Nov 2020View details →
zenodo28/100

Figure 7 from: Avila-Poveda OH (2020) Large-scale project 'Chiton of the Mexican Tropical Pacific': Chiton articulatus (Mollusca: Polyplacophora). Research Ideas and Outcomes 6: e60446. https://doi.org/10.3897/rio.6.e60446

Figure 7 Group of volunteers and collaborators of the QUITÓN PROJECT in FACIMAR-UAS. The project has a logo registration (brand), which is used on the shirts. Shirts used in the field and presentations (congresses, workshops) are shown.

opencc-by-4.0Nov 2020View details →
zenodo28/100

Figure 6 from: Avila-Poveda OH (2020) Large-scale project 'Chiton of the Mexican Tropical Pacific': Chiton articulatus (Mollusca: Polyplacophora). Research Ideas and Outcomes 6: e60446. https://doi.org/10.3897/rio.6.e60446

Figure 6 Locations of Chiton articulatus collection. The star indicates the local headquarters of this project. The base map was taken from Instituto Nacional de Estadística, Geografía e Informática (INEGI). https://www.inegi.org.mx/

opencc-by-4.0Nov 2020View details →
zenodo28/100

Figure 3 from: Avila-Poveda OH (2020) Large-scale project 'Chiton of the Mexican Tropical Pacific': Chiton articulatus (Mollusca: Polyplacophora). Research Ideas and Outcomes 6: e60446. https://doi.org/10.3897/rio.6.e60446

Figure 3 The food menu of some restaurants in Acapulco, Guerrero, including a dish with chiton, common name "Cucaracha/cockroach".

opencc-by-4.0Nov 2020View details →
zenodo28/100

Figure 2 from: Avila-Poveda OH (2020) Large-scale project 'Chiton of the Mexican Tropical Pacific': Chiton articulatus (Mollusca: Polyplacophora). Research Ideas and Outcomes 6: e60446. https://doi.org/10.3897/rio.6.e60446

Figure 2 Example of sale and consumption of meat (foot, in colloquial Spanish "Lengua") of Chiton articulatus. Sale of chitons in beaches of Acapulco (left upper). Sale of chitons in streets of Pochutla, Oaxaca, close to Huatulco (left lower). Dish (Lengua a la Mexicana) in a restaurant in Huatulco (right upper). Artisanal fishing of chitons for a family weekend reunion at Puerto Angel, Oaxaca close to Huatulco (right lower).

opencc-by-4.0Nov 2020View details →
zenodo28/100

Figure 9 from: Avila-Poveda OH (2020) Large-scale project 'Chiton of the Mexican Tropical Pacific': Chiton articulatus (Mollusca: Polyplacophora). Research Ideas and Outcomes 6: e60446. https://doi.org/10.3897/rio.6.e60446

Figure 9 Collage (application letters) of the procedure to request the recognition and incorporation of this Chiton articulatus mollusc into the National Fisheries Chart.

opencc-by-4.0Nov 2020View details →
zenodo28/100

Multi-objective optimization data (large scale truss)

<p>The file contains data obtained from the multi-objective optimization of a large scale truss</p>

opencc-by-4.0Dec 2020View details →
zenodo28/100

Reproducible results for: pmparser and PMDB: resources for large-scale, open studies of the biomedical literature

<p>The zip file contains all code and results. See the included readme.</p>

opengpl-2.0-or-laterSep 2020View details →
dryad28/100

Data from: Towards large scale automated cage monitoring – Diurnal rhythm and impact of interventions on in-cage activity of C57BL/6J mice recorded 24/7 with a non-disrupting capacitive-based technique

Abstract Background and aims Automated recording of laboratory animal's home cage behavior is receiving increasing attention since such non-intruding surveillance will aid in the unbiased understanding of the normal animal cage behavior potentially improving animal experimental reproducibility. Material and methods Here we investigate activity of group held (5 mice/cage) female C57BL/6J mice (mus musculus) housed in standard Individually Ventilated Cages (IVC cages) across three test-sites: Consiglio Nazionale delle Ricerche (Rome, Italy), The Jackson Laboratory (Bar Harbor, USA) and Karolinska Insititutet (Stockholm, Sweden). Additionally, comparison of female and male C57BL/6J mice was done at KI. Activity was recorded using a capacitive-based sensor placed non-intrusively on the cage rack under the home cage collecting activity data every 250 msec, 24/7. The data collection was analyzed using non-parametric rank-based analysis of variance (nparLD) for longitudinal data comparing sites, weekdays and sex. Results The system detected an increase in activity preceding and peaking around lights-on followed by a decrease to a rest pattern. At lights off, activity increased substantially displaying a distinct temporal variation across this period. We also documented impact on mouse activity that standard animal handling procedures have, e.g. cage-changes, and show that even simple procedures are stressors impacting in-cage activity. These key observations replicated across the three test-sites, however, it is also clear that, apparently minor local environmental differences generate significant behavioral variances between the sites and within sites across weeks. Comparison of gender revealed differences in activity in the response to cage-change lasting for days in male but not female mice; and apparently also impacting the response to other events such as lights-on in males. Females but not males showed a larger tendency for week-to-week variance in activity possibly reflecting estrous cycling. Conclusions These data demonstrate that real-time home cage monitoring is scalable and run in real time, providing complementary information for animal welfare measures, experimental design and phenotype characterization.

opencc-zeroDec 2018View details →
dryad28/100

Data from: Large-scale functional networks identified from resting-state EEG using spatial ICA

Several methods have been applied to EEG or MEG signals to detect functional networks. In recent works using MEG/EEG and fMRI data, temporal ICA analysis has been used to extract spatial maps of resting-state networks with or without an atlas-based parcellation of the cortex. Since the links between the fMRI signal and the electromagnetic signals are not fully established, and to avoid any bias, we examined whether EEG alone was able to derive the spatial distribution and temporal characteristics of functional networks. To do so, we propose a two-step original method: 1) An individual multi-frequency data analysis including EEG-based source localisation and spatial independent component analysis, which allowed us to characterize the resting-state networks. 2) A group-level analysis involving a hierarchical clustering procedure to identify reproducible large-scale networks across the population. Compared with large-scale resting-state networks obtained with fMRI, the proposed EEG-based analysis revealed smaller independent networks thanks to the high temporal resolution of EEG, hence hierarchical organization of networks. The comparison showed a substantial overlap between EEG and fMRI networks in motor, premotor, sensory, frontal, and parietal areas. However, there were mismatches between EEG-based and fMRI-based networks in temporal areas, presumably resulting from a poor sensitivity of fMRI in these regions or artefacts in the EEG signals. The proposed method opens the way for studying the high temporal dynamics of networks at the source level thanks to the high temporal resolution of EEG. It would then become possible to study detailed measures of the dynamics of connectivity.

opencc-zeroDec 2015View details →
dryad28/100

Data from: Large-scale proteomics of the cassava storage root and identification of a target gene to reduce post-harvest deterioration

Cassava (Manihot esculenta) is the most important root crop in the tropics, but rapid postharvest physiological deterioration (PPD) of the root is a major constraint to commercial cassava production. We established a reliable method for image-based PPD symptom quantification and used label-free quantitative proteomics to generate an extensive cassava root and PPD proteome. Over 2600 unique proteins were identified in the cassava root, and nearly 300 proteins showed significant abundance regulation during PPD. We identified protein abundance modulation in pathways associated with oxidative stress, phenylpropanoid biosynthesis (including scopoletin), the glutathione cycle, fatty acid α-oxidation, folate transformation, and the sulfate reduction II pathway. Increasing protein abundances and enzymatic activities of glutathione-associated enzymes, including glutathione reductases, glutaredoxins, and glutathione S-transferases, indicated a key role for ascorbate/glutathione cycles. Based on combined proteomics data, enzymatic activities, and lipid peroxidation assays, we identified glutathione peroxidase as a candidate for reducing PPD. Transgenic cassava overexpressing a cytosolic glutathione peroxidase in storage roots showed delayed PPD and reduced lipid peroxidation as well as decreased H2O2 accumulation. Quantitative proteomics data from ethene and phenylpropanoid pathways indicate additional gene candidates to further delay PPD. Cassava root proteomics data are available at www.pep2pro.ethz.ch for easy access and comparison with other proteomics data.

opencc-zeroDec 2013View details →
dryad28/100

Data from: Improving short-term information spreading efficiency in scale-free networks by specifying top large-degree vertices as the initial spreaders.

The positive function of initially influential vertices could be exploited to improve spreading efficiency for short-term spreading in scale-free networks. However, the selection of initial spreaders depends on the specific scenes. The selection of initial spreaders needs to offer low complexity and low power consumption for short-term spreading. In this paper, we propose a selection strategy for efficiently spreading information by specifying a set of top large-degree vertices as the initially informed vertices. The essential idea behind the proposed selection strategy is to exploit the significant diffusion of the top large-degree vertices at the beginning of spreading. To evaluate the positive impact of initially influential vertices, we first build an information spreading model in the Barabási-Albert (BA) scale-free network; next, we design 54 comparative Monte Carlo experiments based on a benchmark strategy and the proposed selection strategy in different BA scale-free network structures. Experimental results indicate that (1) the proposed selection strategy significantly can improve spreading efficiency in the short-term spreading and (2) both network size and number of hubs have a strong impact on spreading efficiency, while the number of initially informed vertices has a weak impact. The proposed selection strategy can be employed in short-term spreading, such as sending warnings or crisis information spreading or information spreading in emergency training or realistic emergency scenes.

opencc-zeroDec 2017View details →
dryad28/100

Data from: Large-scale natural disturbance alters genetic population structure of the sailfin molly, Poecilia latipinna

Many inferences about contemporary rates of gene flow are based on the assumption that the observed genetic structure among populations is stable. Recent studies have uncovered several cases in which this assumption is tenuous. Most of those studies have focused on the effects that regular environmental fluctuations can have on genetic structure and gene flow patterns. Occasional catastrophic disturbances could also alter either the distribution of habitat or the spatial distribution of organisms in a way that affects population structure. However, evidence of such effects is sparse in the literature because it is difficult to obtain. Hurricanes, in particular, have the potential to exert dramatic effects on population structure of organisms found on islands or coral reefs or in near shore and coastal habitats. Here we draw on a historic genetic data set and new data to suggest that the genetic structure of sailfin molly (Poecilia latipinna) populations in north Florida was altered dramatically by an unusually large and uncommon type of storm surge associated with Hurricane Dennis in 2005. We compare the spatial pattern of genetic variation in these populations after Hurricane Dennis to the patterns described in an earlier study in this same area. We use comparable genetic data from another region of Florida, collected in the same two periods, to estimate the amount of change expected from typical temporal variation in population structure. The comparative natural history of sailfin mollies in these two regions indicates that the change in population structure produced by the storm surge is not the result of many local extinctions with recolonization from a few refugia but emerged from a pattern of mixing and redistribution.

opencc-zeroDec 2011View details →
dryad28/100

Data from: Large-scale genotyping of highly polymorphic loci by next generation sequencing: how to overcome the challenges to reliably genotype individuals?

Studying the different roles of adaptive genes is still a challenge in evolutionary ecology and requires reliable genotyping of large numbers of individuals. Next-generation sequencing (NGS) techniques enable such large-scale sequencing, but stringent data processing is required. Here, we develop an easy to use methodology to process amplicon-based NGS data and we apply this methodology to reliably genotype four major histocompatibility complex (MHC) loci belonging to MHC class I and II of Alpine marmots (Marmota marmota). Our post-processing methodology allowed us to increase the number of retained reads. The quality of genotype assignment was further assessed using three independent validation procedures. A total of 3069 high-quality MHC genotypes were obtained at four MHC loci for 863 Alpine marmots with a genotype assignment error rate estimated as 0.21%. The proposed methodology could be applied to any genetic system and any organism, except when extensive copy-number variation occurs (that is, genes with a variable number of copies in the genotype of an individual). Our results highlight the potential of amplicon-based NGS techniques combined with adequate post-processing to obtain the large-scale highly reliable genotypes needed to understand the evolution of highly polymorphic functional genes.

opencc-zeroDec 2014View details →
dryad28/100

Data from: Crowdsourced geometric morphometrics enable rapid large-scale collection and analysis of phenotypic data

1. Advances in genomics and informatics have enabled the production of large phylogenetic trees. However, the ability to collect large phenotypic datasets has not kept pace. 2. Here, we present a method to quickly and accurately gather morphometric data using crowdsourced image-based landmarking. 3. We find that crowdsourced workers perform similarly to experienced morphologists on the same digitization tasks. We also demonstrate the speed and accuracy of our method on seven families of ray-finned fishes (Actinopterygii). 4. Crowdsourcing will enable the collection of morphological data across vast radiations of organisms, and can facilitate richer inference on the macroevolutionary processes that shape phenotypic diversity across the tree of life.

opencc-zeroDec 2014View details →
dryad28/100

Data from: Large-scale fungal diversity assessment in the Andean Yungas forests reveals strong community turnover among forest types along an altitudinal gradient

The Yungas, a system of tropical and subtropical montane forests on the eastern slopes of the Andes, are extremely diverse and severely threatened by anthropogenic pressure and climate change. Previous mycological works focused on macrofungi (e.g., agarics, polypores) and mycorrhizae in Alnus acuminata forests, while fungal diversity in other parts of the Yungas has remained mostly unexplored. We carried out Ion Torrent sequencing of ITS2 rDNA from soil samples taken at 24 sites along the entire latitudinal extent of the Yungas in Argentina. The sampled sites represent the three altitudinal forest types: the piedmont (400–700 masl), montane (700–1500 masl), and montane cloud (1500–3000 masl) forests. The deep sequence data presented here (i.e. 4 108 126 quality-filtered sequences) indicate that fungal community composition correlates most strongly with elevation, with many fungi showing preference for a certain altitudinal forest type. For example, ectomycorrhizal and root endophytic fungi were most diverse in the montane cloud forests, particularly at sites dominated by Alnus acuminata, while the diversity values of various saprobic groups were highest at lower elevations. Despite the strong altitudinal community turnover, fungal diversity was comparable across the different zonal forest types. Besides elevation, soil pH, N, P, and organic matter contents correlated with fungal community structure as well, although most of these variables were co-correlated with elevation. Our data provide an unprecedented insight into the high diversity and spatial distribution of fungi in the Yungas forests.

opencc-zeroDec 2013View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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