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910 results for “Headache”
Dataset related to article "Profiling the Spectrum of Headache Disorders on 440 Breast Cancer Patients: Highlights on Clinical and Pathological Mechanisms"
<p>This record contains raw data related to article "Profiling the Spectrum of Headache Disorders on 440 Breast Cancer Patients: Highlights on Clinical and Pathological Mechanisms"</p><p>Abstract</p><p>Although widely studied, the association between migraines (M) and breast cancer (BC) risk remains evasive. In this prospective single-center study, 440 early or locally advanced BC patients were enrolled at IRCCS Humanitas Research Hospital. Clinical and demographical data were collected. Those who suffered from headaches were evaluated with the International Classification of Headache Disorders. M was found to be significantly more prevalent in BC patients: 56.1% versus an expected prevalence of 17% in the global population. M patients showed a higher risk of having stage II or III BC than stage I, which was more frequently found in the non-headache population. Interestingly, the frequency of headache attacks was positively correlated with estrogen (<i>r</i> = 0.11, <i>p</i> = 0.05) and progesterone (<i>r</i> = 0.15, <i>p</i> = 0.007) expression, especially in patients with migraine without aura. The higher the expression of hormone receptors in BC, the higher the headache frequency. Moreover, patients suffering from headaches showed an overall earlier onset of BC. Our findings challenge the idea of a net preventive role of M on BC, suggesting a rather complex interaction in which M mostly influences some BC subtypes and vice versa. Further multi-center studies with extended follow-up are needed.</p>
Dataset related to article "Imaging Correlates between Headache and Breast Cancer: An [18F]FDG PET Study"
<p>This record contains raw data related to article "Imaging Correlates between Headache and Breast Cancer: An [18F]FDG PET Study"</p><p><strong>Abstract</strong></p><p>This study aimed to examine brain metabolic patterns on [18F]Fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) in breast cancer (BC), comparing patients with tension-type headache (TTH), migraine (MiG), and those without headache. Further association with BC response to neoadjuvant chemotherapy (NAC) was explored. In this prospective study, BC patients eligible for NAC performed total-body [18F]FDG PET/CT with a dedicated brain scan. A voxel-wise analysis (two-sample <i>t</i>-test) and a multiple regression model were used to compare brain metabolic patterns among TTH, MiG, and no-headache patients and to correlate them with clinical covariates. A single-subject analysis compared each patient's brain uptake before and after NAC with a healthy control group. Primary headache was diagnosed in 39/46 of BC patients (39% TTH and 46% MiG). TTH patients exhibited hypometabolism in specific brain regions before NAC. TTH patients with a pathological complete response (pCR) to NAC showed hypermetabolic brain regions in the anterior medial frontal cortex. The correlation between tumor uptake and brain metabolism varied before and after NAC, suggesting an inverse relationship. Additionally, the single-subject analysis revealed that hypometabolic brain regions were not present after NAC. Primary headache, especially MiG, was associated with a better response to NAC. These findings suggest complex interactions between BC, headache, and hormonal status, warranting further investigation in larger prospective cohorts.</p>
dataset related to article "Comorbidities of primary headache disorders: a literature review with meta-analysis"
<p><strong>Raw data extracted from the different manuscripts included in the review with meta-analysis</strong></p> <p> </p>
Anodal transcranial direct current stimulation in chronic migraine and medication overuse headache: A pilot double-blind randomized sham-controlled trial
<p>This dataset includes raw data from the article “Anodal transcranial direct current stimulation in chronic migraine and medication overuse headache: A pilot double-blind randomized sham-controlled trial”.</p> <p>In this study, we enrolled 20 patients with chronic migraine (CM) and medication overuse headache (MOH). They were hospitalized for a 7-day detoxification treatment and were randomly assigned to anodal tDCS or sham stimulation delivered over the primary motor cortex contralateral to the prevalent migraine pain side every day for 5 days. Clinical data were recorded at baseline (T0), after 1 month (T2) and 6 months (T3). EEG recording was performed at T0, at the end of the tDCS/Sham treatment, and at T2.</p> <p>At T2 and T3, we found a significant reduction in monthly migraine days (p = 0.001), which were more pronounced in the tDCS group when compared to the sham group (p = 0.016). At T2, we found a significant increase of alpha rhythm in occipital leads, which was significantly higher in tDCS group when compared to sham group. In conclusion, tDCS showed adjuvant effects to detoxification in the management of patients with CM and MOH. The EEG recording showed a significant potentiation of alpha rhythm, which may represent a correlate of the underlying changes in cortico-thalamic connections.</p>
Dataset related to article "Different Personality Profiles In Patients With Chronic Cluster Headache: A Data-Driven Approach"
<p>dataset contains clinical information on patient involved in the study described at article at title</p>
20210804_erenumab_Headache_SB_01
<p>Dataset refers to the evaluation of psychological predictors of the outcome of 12-month of treatment with Erenumab in Chronic Migraine patients: Responders (reduction ≥ 50% in migraine days) vs Non Responders (reduction < 50% in migraine days). To this end, patients at baseline received a full psychological evaluation using The Structured Clinical Interview for DSM-5 Clinician Version (SCID-5-CV) to assess mood, anxiety, and personality disorders as well specific questionnaires to evaluate alexithymia traits, childhood traumas, and current life-event stressors. Results highlighted that the presence of current stressors, anxiety and Cluster C personality disorders represent negative predictors of treatment outcome.</p>
20210716_SDS_Headache_SB_01
<p>Dataset refers to the validation of the Severity of Dependence Scale (SDS) in detecting dependence behaviors in patients with chronic migraine and medication overuse using the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) and the Leeds Dependence Questionnaire (LDQ) as gold standard measures. In the dataset are reported scores in single items of the SDS and LDQ according to the diagnosis made by DSM-IV. Results highlighted significantly higher SDS scores in patients with substance dependence with respect to those without this diagnosis.</p>
Dataset related to Article "A SINGLE-GROUP STUDY ON THE EFFECT OF ONABOTULINUMTOXINA IN PATIENTS WITH CHRONIC MIGRAINE ASSOCIATED TO MEDICATION OVERUSE HEADACHE: PAIN CATASTROPHIZING PLAYS A ROLE"_ submitted
<p>THIS DATASET INCLUDES INFORMATION ON HEADACHE FREQUENCY, MEDICATION INTAKE, MIDAS SCORE, AVERAGE PAIN, HIT-6, ASC-12 AND PCS REFERRED TO PATIENTS RECEIVING ONABOTULINUMTOXINA AS PROPHYLAXIS FOR CM-MOH OVER 12 MONTHS.</p>
Data related to article EFFICACY OF MINDFULNESS ADDED TO TREATMENT AS USUAL IN PATIENTS WITH CHRONIC MIGRAINE AND MEDICATION OVERUSE HEADACHE: A PHASE-III SINGLE-BLIND RANDOMIZED-CONTROLLED TRIAL (THE MIND-CM STUDY) - submitted
<p>DATA ON PATIENTS INCLUDED IN THE MIND-CM STUDY. TWO ARMS (TAU AND TAU+MIND), AND FOUR EVALUATIONS: BASELINE, 3-MONTHS, 6-MONTHS AND 12-MONTS FOLLOW-UP.</p>
Personality in chronic headaches: A systematic review with meta-analysis
<p>Dataset refers to a systematic review on the personality traits associated to Chronic Headache (CH) compared to healthy controls and to a quantitative meta-analysis with the studies using the same instrument to assess personality traits. Thirteen studies were included in the systematic review but only three studies were deeply explored in a meta-analysis since the only ones using a common instrument to assess personality dimensions. According to the results of the meta-analysis, different subtypes of CH patients scored higher than healthy controls on Hypochondriasis and Hysteria scales highlighting that these personality traits are common across CH categories. The systematic review showed higher levels of depressive and anxious personality dimensions and pain catastrophizing in CH compared to healthy controls. Moreover, frequent-chronic forms and Medication Overuse Headache were the most symptomatic and frail categories showing higher levels of dysfunctional personality traits and psychopathological symptoms</p>
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International Brain Laboratory public data
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OpenNeuro
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