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2,435
datasets available to search
ShareScore release 0.9.0
Dataset results
2,435 results for “Metastasis”
Gene signatures of progression and metastasis in renal cell cancer
GEO Series GSE15641. Homo sapiens. 92 samples. Type: Expression profiling by array.
Immune evasion in lung metastasis of leiomyosarcoma: upregulation of EPCAM inhibits CD8⁺ T cell infiltration
GEO Series GSE250089. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
The RhoA guanine nucleotide exchange factor Net1 is required for PyMT mediated mammary gland tumorigenesis and metastasis
GEO Series GSE99643. Mus musculus. 6 samples. Type: Expression profiling by array.
Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Breast Cancer Bone Metastasis
GEO Series GSE108250. Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing.
TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer
GEO Series GSE267533. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Single-cell profiling reveals altered immune landscape and impaired NK cell function in gastric cancer liver metastasis
GEO Series GSE246662. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Primary tumor grafts as advanced models for breast cancer that authentically reflect tumor histopathology, growth, metastasis, and patient outcomes (copy number)
GEO Series GSE32530. Homo sapiens. 24 samples. Type: Genome variation profiling by SNP array.
Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis [RNA-Seq]
GEO Series GSE215757. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis [ChIP-seq]
GEO Series GSE196897. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Macrophages reprogramming improves immunotherapy of IL-33 in peritoneal metastasis of gastric cancer
GEO Series GSE235526. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
llumina 450k array was used to identify DNA methylation data from formalin-fixed paraffine-embedded (FFPE) human uveal melanoma correlated to gene expression, metastasis and poor prognosis
GEO Series GSE156876. Homo sapiens. 23 samples. Type: Methylation profiling by array.
Fusobacterium nucleatum Promotes Metastasis of Breast Cancer via the miR-21-3p/FOXO3 Axis
GEO Series GSE298584. Homo sapiens. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Antagonizing miR-128 abrogates chemoresistance-associated metastasis and is therapeutic in non-small cell lung cancer
GEO Series GSE67729. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by array; Expression profiling by array.
Data from: Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis
Platelets modulate the process of cancer metastasis. However, current knowledge on the direct interaction of platelets and tumor cells is mostly based on findings obtained in vitro. We addressed the role of the platelet fibrinogen receptor glycoprotein IIb (integrin αIIb) for experimental melanoma metastasis in vivo. Highly metastatic B16-D5 melanoma cells were injected intravenously into GPIIb-deficient (GPIIb-/-) or wildtype (WT) mice. Acute accumulation of tumor cells in the pulmonary vasculature was assessed in real-time by confocal videofluorescence microscopy. Arrest of tumor cells was dramatically reduced in GPIIb-/- mice as compared to WT. Importantly, we found that mainly multicellular aggregates accumulated in the pulmonary circulation of WT, instead B16-D5 aggregates were significantly smaller in GPIIb-/- mice. While pulmonary arrest of melanoma was clearly dependent on GPIIb in this early phase of metastasis, we also addressed tumor progression 10 days after injection. Inversely, and unexpectedly, we found that melanoma metastasis was now increased in GPIIb-/- mice. In contrast, GPIIb did not regulate local melanoma proliferation in a subcutaneous tumor model. Our data suggest that the platelet fibrinogen receptor has a differential role in the modulation of hematogenic melanoma metastasis. While platelets clearly support early steps in pulmonary metastasis via GPIIb-dependent formation of platelet-tumor-aggregates, at a later stage its absence is associated with an accelerated development of melanoma metastases.
Data and code for "Genomic–transcriptomic evolution in lung cancer and metastasis"
<p>Processed data and code to generate all main figures and extended data figures for the manuscript "Genomic–transcriptomic evolution in lung cancer and metastasis" (transcriptomics_scripts_data_20230330.zip) as well as data and code to run the ensemble machine learning classifier to predict metastatic potential (pred_met_2023.zip).</p>
Recurrence and metastasis detection of breast cancer
<p>This dataset includes clinical data from 126 patients which were pathologically diagnosed as invasive cancer and all received adjuvant trastuzumab treatment. Among them, 31 patients suffered from recurrence or metastasis. In addition, 84 H&E stained whole slide images (WSI) of breast cancer were downloaded from TCGA (https://portal.gdc.cancer.gov/repository/), of which 19 cases have recurrence or metastasis. </p>
Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Trastuzumab in Breast Cancer With Leptomeningeal Metastasis
ClinicalTrials.gov study NCT07263425. IPD Sharing: YES. Countries: 1. Publications: 0.
Sorafenib-RT Treatment for Liver Metastasis (SLIM)
ClinicalTrials.gov study NCT00892424. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Artificial Intelligence-based Model for the Prediction of Occult Lymph Node Metastasis and Improvement of Clinical Decision-making in Non-small Cell Lung Cancer
ClinicalTrials.gov study NCT06684418. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma Following Local Ablation
ClinicalTrials.gov study NCT03356236. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.