Find research datasets worth reusing

Inter-spike Intervals Data for pulsed an dsinusoidal modulation

In this dataset you can find the inter-spike intervals experimental data recorded under pulsed and sinusoidal modulation and a given Idc value for a semiconductor laser under optical feedback and current modulation. The DC pump current ranges from 25.5 to 27.5mA and the modulation amplitude from 30 to 100 (arb units) while the modulation frequency ranges from 1 to 80 MHz.

Using Powder Diffraction Patterns to Calibrate the Module Geometry of a Pixel Detector

Powder diffraction data and jupyter notebooks to accompany the publication:  "Using Powder Diffraction Patterns to Calibrate the Module Geometry of a Pixel Detector" <a href="https://sciprofiles.com/profile/142400">Jonathan P. Wright</a>, <a href="https://sciprofiles.com/profile/author/Wjg3TE9sVlJleUs2bC9IaVdNeXczVFlwK2p6eW9JTWhoREJiSEZnaWw1TT0=">Carlotta Giacobbe</a> and <a href="https://sciprofiles.com/profile/author/V3JYR2UvT1pjTFdPMWF6Y0pidGdNcHlaQndxMHJOK3pNTkFaRmZaMkU5UT0=">Eleanor Lawrence Bright</a> Crystals 2022, 12(2), 255; <a href="https://doi.org/10.3390/cryst12020255">https://doi.org/10.3390/cryst12020255</a>

opencc-zeroMar 2022View details →

Data from: Host sex modulates the energetics of pathogen proliferation and its dependence on environmental resources

Sex differences in immunity are predicted to underlie much of the frequently observed sex differences in the prevalence or severity of infection. We propose the additional hypothesis that differences in the ability of males and females to acquire and use resources will also affect how readily a pathogen can convert host energy into transmission stages, thereby contributing to sex differences in infection dynamics. To test this we manipulated the resource environment of male and female Daphnia magna by altering the availability of food and then exposed hosts to a bacterial pathogen. We measured the production of transmission spores and virulence via the reduction in life span, together with feeding rates and changes in mass-independent metabolic rate, as a measure of the intake and expenditure of energy during infection. When raised in the presence of high resource levels, females more readily allowed for resources in the environment to be translated to pathogen exploitation, as represented by increased spore production, greater virulence, and higher energy use. In contrast, the traits of infected males were robust to changes in resource availability. High food availability thus exaggerated the degree of sexual dimorphism observed between the sexes. It also modified the relationship between host energy use, virulence, and pathogen spore production for each sex. These results suggest that a host's resource environment can affect how a male or female is exploited by a pathogen and may thus be an additional factor driving sex-specific patterns of disease susceptibility or severity.

Skin stretch modulates tactile distance perception without central correction mechanisms

Data and analysis code accompanying the manuscript.

Walking stride modulations in Drosophila HS cells, data and MATLAB analysis codes

Data and MATLAB analysis codes for an article titled: Walking strides direct rapid and flexible recruitment of visual circuits for course control in Drosophila.

opencc-zeroApr 2022View details →

Plant landscape abundance and soil fungi modulate drought effects on plant-soil feedbacks

Plant-soil feedbacks (PSF) play an important role in determining plant community structure and dynamics. However, previous studies have provided mixed results for the relationship between PSF and plant landscape abundance (i.e., abundance across local communities). This may reflect the mediation of climate factors on PSF. Here, we tested how PSF of tree species varied with local abundances by growing seedlings in conspecific versus heterospecific soil and how simulated drought altered PSF-plant abundance relationships. Six tree species were selected and half of the seedlings were grown under ambient moisture conditions, while the others experienced a 2-month period of drought following 3-months of growth under ambient moisture conditions. Fungal communities in the rhizosphere soil were analysed using DNA amplicon sequencing to link shifts in soil fungi to the observed PSF. We found that drought reduced negative PSF for all plant species except one species (Lithocarpus lohangwu). In the drought treatments, PSF were positively correlated with the relative abundance of total putative pathogens, but negatively correlated with the proportion of unique pathogens (those pathogens that were present in conspecific soil rather than heterospecific soil, thereby potentially species-specific). In addition, we found that PSF only significantly predicted plant relative abundance in the drought treatment, indicating that abiotic stress made PSF a stronger predictor of plant landscape abundance. This finding also implies that future extreme drought events could promote the dominance of the abundant plant species, thereby leading to the loss of biodiversity. Collectively, our results provide evidence for microbial mechanisms of PSF and suggest that accounting for abiotic stress can make PSF a stronger predictor of plant landscape abundance due to the omnipresence of stress under natural conditions.

Data and code for figures of "Gigahertz free-space electro-optic modulators based on Mie resonances" by Benea-Chelmus et al.

This upload contains the main dataset represented in the figures of the following publication: "Gigahertz free-space electro-optic modulators based on Mie resonances"" by Benea-Chelmus et al.

Micromagnetics of magnetic chemical modulations in soft-magnetic cylindrical nanowires

Abstract: We analyze the micromagnetics of short longitudinal modulations of a high magnetization material in cylindrical nanowires made of a soft-magnetic material of lower magnetization such as Permalloy, combining magnetic microscopy, analytical modeling and micromagnetic simulations. The mismatch of magnetization induces curling of magnetization around the axis in the modulations, in an attempt to screen the interfacial magnetic charges. The curling angle increases with modulation length, until a plateau is reached with nearly full charge screening for a specific length scale, larger than the dipolar exchange length of any of the two materials. The curling circulation can be switched by the &OElig;rsted field arising from a charge current with typical magnitude 1012A/m2.

opencc-by-4.0May 2021View details →

Data from: Olfactory modulation of barrel cortex activity during active whisking and passive whisker stimulation

Rodents depend on olfaction and touch to meet many of their fundamental needs. The joint significance of these sensory systems is underscored by an intricate coupling between sniffing and whisking. However, the impact of simultaneous olfactory and tactile inputs on sensory representations in the cortex remains elusive. To study these interactions, we recorded large populations of barrel cortex neurons using 2-photon calcium imaging in head-fixed mice during olfactory and tactile stimulation. We find that odors alter barrel cortex activity in at least two ways, first by enhancing whisking, and second by central cross-talk that persists after whisking is abolished by facial nerve sectioning. Odors can either enhance or suppress barrel cortex neuronal responses, and while odor identity can be decoded from population activity, it does not interfere with the tactile representation. Thus, barrel cortex represents olfactory information which, in the absence of learned associations, is coded independently of tactile information.

Data used in "Topographic Modulation of the Wind Stress Impact on Eddy Activity in the Southern Ocean"

These are the data used in the creation of figures (Fig3,4,S2) in Cai et al. 2022: "Topographic Modulation of the Wind Stress Impact on Eddy Activity in the Southern Ocean", including 9 experiments. It is obtained from NEMO output.

opencc-by-4.0Jun 2022View details →

Self-assembling peptide nanofiber HIV vaccine elicits robust vaccine-induced antibody functions and modulates Fc glycosylation.

To develop vaccines for certain key global pathogens such as HIV, it is crucial to elicit both neutralizing and non-neutralizing Fc-mediated effector antibody functions. Clinical evidence indicates that non-neutralizing antibody functions including antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) contribute to protection against several pathogens. In this study, we demonstrated that conjugation of HIV Envelop (Env) antigen gp120 to a self-assembling nanofiber material named Q11 induced antibodies with higher breadth and functionality when compared to soluble gp120. Immunization with Q11-conjugated gp120 vaccine (gp120-Q11) demonstrated higher tier 1 neutralization, ADCP and ADCC as compared to soluble gp120. Moreover, Q11 conjugation altered the Fc N-glycosylation profile of antigen-specific antibodies, leading to a phenotype associated with increased ADCC in animals immunized with gp120-Q11. Thus, this nanomaterial vaccine strategy can enhance non-neutralizing antibody functions possibly through modulation of IgG Fc N-glycosylation.

opencc-by-4.0Jul 2022View details →

Data Archive of 'Hadley Cell Edge Modulates the Role of Ekman Heat Flux in a Future Climate'

Output data used to create figures in ' Hadley Cell Edge Modulates the Role of Ekman Heat Flux in a Future Climate ' is archived. Original data sources from which the output data are generated are Reanalysis Products (ERA5, JRA55, NCEP/NCAR reanalysis) and 8 CMIP6 model simulations.

opencc-by-4.0Aug 2022View details →

Modulation of Cyclones with Tropical and Extratropical Origins by Mesoscale SSTs in the Kuroshio Extension Region

Datasets for Modulation of Cyclones with Tropical and Extratropical Origins by Mesoscale SSTs in the Kuroshio Extension Region.

Data for "Syntactic modulation of rhythm in Australian pied butcherbird song"

Australian pied butcherbird song data necessary for reproducing results in "Syntactic modulation of rhythm in Australian pied butcherbird song".  Code to reproduce results are found in: https://github.com/xingjeffrey/syntax_rhythm_pbb All WAV files in this data repository have been transformed into .pickle format to respect the wishes of the author who contributed the field recordings. The WAV files were only involved in generating spectrograms for computation/manual annotations, and are not absolutely necessary for reproducing the statistical analyses of this study. If needed, the .pickle files corresponding to the WAV files may be used to generate waveforms of the analyzed Australian pied butcherbird songs. If you have any concerns or questions, contact the corresponding author (Jeffrey Xing) at j8xing@ucsd.edu

opencc-zeroSep 2022View details →

Head and mandible shapes are highly integrated yet represent two distinct modules within and among worker sub-castes of the ant genus Pheidole

Ants use their mandibles for a wide variety of tasks related to substrate manipulation, brood transport, food processing, and colony defence. Due to constraints involved in colony upkeep, ants evolved a remarkable diversity of mandibular forms, often related to specific roles such as specialized hunting and seed milling. Considering these varied functional demands, we focused on understanding how the mandible and head shape vary within and between Pheidole sub-castes. Using x-ray microtomography and 3D geometric morphometrics, we tested if these structures are integrated and modular, and how ecological predictors influenced these features. Our results showed that mandible and head shape of majors and minor workers tend to vary from robust to slender, with some more complex changes related to the mandibular base. Additionally, we found that head and mandible shapes are characterized by a high degree of integration, but with little correlation with feeding and nesting habits. Our results suggest that a combination of structural (allometric) constraints and the behavioural flexibility conferred by caste dimorphism might largely buffer selective pressures that would otherwise lead to a fine-tuning between ecological conditions and morphological adaptation.

opencc-zeroSep 2022View details →

Locomotor resilience through load-dependent modulation of muscle co-contraction

Terrestrial locomotor behavior in variable environments requires resilience to sudden changes in substrate properties. For example, walking animals can adjust to substantial changes in slope and corresponding changes in load distribution among legs. In insects, slope-dependent adjustments have mainly been examined under steady-state conditions, whereas the transition dynamics have been largely neglected. In a previous study, we showed that steady-state adjustments of stick insects to ±45° slopes involve substantial changes in joint torques and muscle activity with only minor changes in leg kinematics. Here, we take a close look at the time course of these adjustments as stick insects compensate for various kinds of disturbances to load distribution. In particular, we test whether the transition from one steady state to another involves distinct transition steps or follows a graded process. To resolve this, we combined simultaneous recordings of whole-body kinematics and hind leg muscle activity to elucidate how freely walking Carausius morosus negotiated a step-change in substrate slope. Step-by-step adjustments reveal that muscle activity changed in a graded manner as a function of body pitch relative to gravity. We further show analogous transient adjustment of muscle activity in response to destabilizing lift-off events of neighboring legs and the disappearance of antagonist co-activation during crawling episodes. Given these three examples of load-dependent regulation of antagonist muscle co-contraction, we conclude that stick insects respond to both transient and sustained changes in load distribution by regulating joint stiffness rather than through distinct transition steps.

opencc-by-4.0Jul 2021View details →

Modulation of 5-LOX activity and comparison with COX-2 activity by (poly)phenols in cellular models.

5-Lipoxygenase (5-LOX) plays a key role in inflammation through the biosynthesis of leukotrienes and other lipid mediators. Current evidence suggests that dietary (poly)phenols exert a beneficial impact on human health through anti-inflammatory activities. Their mechanisms of action have mostly been associated with the modulation of pro-inflammatory cytokines (TNF-α, IL-1β), prostaglandins (PGE2), and the interaction with NF-κB and cyclooxygenase 2 (COX-2) pathways. Much less is known about the 5-lipoxygenase (5-LOX) pathway as a target of dietary (poly)phenols. This systematic review aimed to summarize how dietary (poly)phenols target the 5-LOX pathway in preclinical and human studies. The number of studies identified is low (5, 24, and 127 human, animal, and cellular studies, respectively) compared to the thousands of studies focusing on the COX-2 pathway. Some (poly)phenolics such as caffeic acid, hydroxytyrosol, resveratrol, curcumin, nordihydroguaiaretic acid (NDGA), and quercetin have been reported to reduce the formation of 5-LOX eicosanoids in vitro. However, the in vivo evidence is inconclusive because of the low number of studies and the difficulty of attributing effects to (poly)phenols. Therefore, increasing the number of studies targeting the 5-LOX pathway would largely expand our knowledge on the anti-inflammatory mechanisms of (poly)phenols.

opencc-by-4.0Aug 2017View details →

Spectral characterization of a supercontinuum source based on self-phase modulation in an aqueous K$_{2}$ZnCl$_{4}$ salt solution

Spectral data and Matlab scripts for analysis, associated with the article "Spectral characterization of a supercontinuum source based on self-phase modulation in an aqueous K$_{2}$ZnCl$_{4}$ salt solution", submitted to Applied Optics.

opencc-by-4.0Jan 2018View details →

Role of the horizontal SST structure in the modulation of heavy precipitations over the Ligurian Sea - time averaged data

Time averaged data used in the analysis the paper Meroni, A. N., A. Parodi and C. Pasquero "Role of the horizontal SST structure in the modulation of heavy precipitations over the Ligurian Sea". The variables are SST,  downwind SST gradient, SST laplacian, surface wind magnitude and convergence.