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927
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ShareScore release 0.9.0
Dataset results
927 results for “genetic study”
A PLURIPOTENT STEM CELL PLATFORM FOR IN VITRO SYSTEMS GENETICS STUDIES OF MOUSE DEVELOPMENT [ATAC-seq]
GEO Series GSE270007. Mus musculus. 31 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metas
ClinicalTrials.gov study NCT04135092. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in Escherichia coli
GEO Series GSE23526. Escherichia coli; Escherichia coli str. K-12 substr. MG1655. 12 samples. Type: Expression profiling by array.
Prediction of Peripheral neuropathy in multiple myeloma patients receiving Bortezomib and Thalidomide: A Genetic Study based on Single Nucleotide Polymorphism Array
GEO Series GSE80278. Homo sapiens. 172 samples. Type: SNP genotyping by SNP array.
Genetic Studies of Osteosarcoma
Investigators in the Clinical Genetics Branch (CGB) are conducting genetic studies of osteosarcoma to better understand the role that genetic variation plays in risk and patient outcomes, and to identify new genes or genomic regions that may be important in osteosarcoma pathogenesis. We estimate that approximately 35,000 germline (blood or buccal cell) DNA samples will be genotyped at the NCI Cancer Genomics Research (CGR) Laboratory and subsequently available for genome-wide association analyses and whole-exome sequencing studies. A team of biostatisticians have created a common control set derived from existing studies that will be used to match controls to the cases. We are conducting large genomic case-control and case-case studies to identify novel common and rare germline variants predisposing to osteosarcoma susceptibility and poor patient outcomes.
A PLURIPOTENT STEM CELL PLATFORM FOR in VITRO SYSTEMS GENETICS STUDIES of MOUSE DEVELOPMENT
GEO Series GSE272490. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing; Other.
Re-evaluating the genetic variation of the COI gene of Insecta: Implications for DNA barcoding, metabarcoding and species delimitation studies
<p>To analyze the genetic variation of the <i>cytochrome c oxidase subunit I</i> (<i>COI</i>) gene of Insecta, the <i>COI</i> data of Insecta was downloaded from GenBank and the intraspecific Kimura-2 -parameter (K2P) distance of 40,782 species was calculated (each species with three or more sequences). Our result indicated that the maximum intraspecific genetic distance of 8,928 (21.89%) species was over 3%. Using a threshold of 3% in the clustering analysis, 7,123 (17.47%) species can be divided into two or more clusters. We also analyzed 3,189 genera with over three species (25,283 species) and found that the optimal thresholds for these genera ranged from 0.1%-15.7% (average value: 0.03531, median value: 0.02900). In clustering analysis, if the threshold values were set to 0.01, 0.02, 0.022, and 0.03, the numbers of clusters were 39,860, 31,024, 29,954, and 26,527, respectively. In metabarcoding studies, a threshold of 0.03 was recommended to estimate the species diversity of insects in a certain environment. However, using the empirical thresholds mentioned above for operational taxonomic unit (OTU) picking, the average match ratios of the 3,189 genera were 0.5137, 0.6338, 0.6440, and 0.6587. By contrast, if the possible thresholds from the distance matrix, the minimum interspecific genetic distance of congeneric species, and the optimal thresholds were used in clustering analysis, the average match ratios of them were 0.6626 0.7530, and 0.7549. Herein, we recommended the utilizations of the minimum interspecific genetic distance (when it was greater than or equal to 2%) and the optimal thresholds for OTU picking in DNA barcoding and species delimitation studies based on the <i>COI</i> gene of insects.</p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.