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Dataset results
978 results for “instabilities”
Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy
GEO Series GSE273576. Homo sapiens. 62 samples. Type: Expression profiling by high throughput sequencing.
Ablation of Id1 Reduces Clonal Hematopoiesis, Genomic Instability and Delays Leukemia in Mice with Tet2 Loss of Function [RNA-seq]
GEO Series GSE266580. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Vhl and Rassf1a mutations cause DNA damage, chromosomal instability and induce gene expression changes characteristic of ccRCC [scRNA-seq]
GEO Series GSE280281. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Hepatitis B virus pre-S2 mutant LHBS induced DNA breakages and genomic instability.
GEO Series GSE61378. Mus musculus. 11 samples. Type: Genome variation profiling by genome tiling array.
Triploid causes genome instability in tumorigenesis
GEO Series GSE32449. Mus musculus. 9 samples. Type: Expression profiling by array.
Vhl and Rassf1a mutations cause DNA damage, chromosomal instability and induce gene expression changes characteristic of ccRCC [bulk RNA-seq]
GEO Series GSE280300. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Maternal mRNA Clearance Prevents Precocious Transcription and Genome Instability in Mouse Early Embryos [S4U-seq]
GEO Series GSE279466. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
PRAME induces genomic instability in uveal melanoma [RNA-seq]
GEO Series GSE231395. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
The data for "Entrapment risk precedes and is more fatal than instability risk in mountainous flash floods"
<p><span>The DEM and inundation depth data of the central area of Liulin Town were obtained by field measurement after the “8.12” flood event.</span></p>
Dataset related to article "Genomic instability analysis in DNA from Papanicolaou test provides proof-of-principle early diagnosis of high-grade serous ovarian cancer"
<p>This record contains data related to the article "Genomic instability analysis in DNA from Papanicolaou test provides proof of principle early diagnosis of high-grade serous ovarian cancer".</p><p>Abstract</p><p>Late diagnosis and the lack of screening methods for early detection define high-grade serous ovarian cancer (HGSOC) as the gynecological malignancy with the highest mortality rate. In the work presented here, we investigated a retrospective and multicentric cohort of 250 archival Papanicolaou (Pap) test smears collected during routine gynecological screening. Samples were taken at different time points (from 1 month to 13.5 years before diagnosis) from 113 presymptomatic women who were subsequently diagnosed with HGSOC (pre-HGSOC) and from 77 healthy women. Genome instability was detected through low-pass whole-genome sequencing of DNA derived from Pap test samples in terms of copy number profile abnormality (CPA). CPA values of DNA extracted from Pap test samples from pre-HGSOC women were substantially higher than those in samples from healthy women. Consistently with the longitudinal analysis of clonal pathogenic <i>TP53</i> mutations, this assay could detect HGSOC presence up to 9 years before diagnosis. This finding confirms the continual shedding of tumor cells from fimbriae toward the endocervical canal, suggesting a new path for the early diagnosis of HGSOC. We integrated the CPA score into the EVA (early ovarian cancer) test, the sensitivity of which was 75% (95% CI, 64.97 to 85.79), the specificity 96% (95% CI, 88.35 to 100.00), and the accuracy 81%. This proof-of-principle study indicates that the early diagnosis of HGSOC is feasible through the analysis of genomic alterations in DNA from endocervical smears.</p>
DRAIC mediates hnRNPA2B1 stability and m6A-modified IGF1R instability to inhibit tumor progression [RNA-seq]
GEO Series GSE244891. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Ribodysgenesis: sudden genome instability in the yeast Saccharomyces cerevisiae arising from RNase H2 cleavage at genomic-embedded ribonucleotides
GEO Series GSE199262. Saccharomyces cerevisiae. 10 samples. Type: Other.
Histone H3G34R mutation causes replicative stress, defective homologous recombination and genomic instability in Fission Yeast
GEO Series GSE96842. Schizosaccharomyces pombe. 9 samples. Type: Expression profiling by high throughput sequencing.
The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability [INDUCE-seq]
GEO Series GSE291629. Homo sapiens. 18 samples. Type: Other.
Overexpression of GLI2 induces genomic instability
GEO Series GSE10132. Homo sapiens. 41 samples. Type: Genome variation profiling by genome tiling array.
Characterization of a clival chordoma xenograft model reveals inherent tumor genomic instability
GEO Series GSE103342. Homo sapiens. 3 samples. Type: Genome variation profiling by SNP array.
Transient genomic instability drives tumorigenesis through accelerated clonal evolution
GEO Series GSE161728. Mus musculus. 81 samples. Type: Expression profiling by high throughput sequencing.
Radiation-Induced Genomic Instability in Caenorhabditis Elegans
GEO Series GSE29979. Caenorhabditis elegans. 8 samples. Type: Expression profiling by array.
Genomic instability induced by furfural-treated in S. cerevisiae [sectored colonies]
GEO Series GSE104880. Saccharomyces cerevisiae. 38 samples. Type: Genome variation profiling by array; Genome variation profiling by SNP array.
Swc4 protects nucleosome free chromatin of telomeres, tRNA genes and rDNA loci to inhibit genome instability [ChIP-Seq]
GEO Series GSE215374. Saccharomyces cerevisiae. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.