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6,699 results for “DEPRESSION”
FIGURE 2 in Stephanodiscus Ehr. species from Holocene sediments in the Faiyum Depression (Middle Egypt)
FIGURE 2. Gross sediment stratigraphies of the three cores, QARU9, QARU10 and GARK1 (see text for sediment descriptions). Note the basal sands below finely laminated diatom marl sediment in QARU9 & 10.
FIGURES 9–14. Stephanodiscus neoaegypticus, SEM. Fig. 9. Iconotype, external valve showing small concentric convex undulation with out spines. Fig. 10 in Stephanodiscus Ehr. species from Holocene sediments in the Faiyum Depression (Middle Egypt)
FIGURES 9–14. Stephanodiscus neoaegypticus, SEM. Fig. 9. Iconotype, external valve showing small concentric convex undulation with out spines. Fig. 10. External valve showing small concentric concave undulation and external rimoportula opening (arrowed). Fig. 11. Internal valve showing sub-marginal rimoportulae (arrowed). Fig. 12. Detail of the same valve showing two sub-marginal rimoportulae and marginal ring fultoportulae. Fig. 13. Detail of the central ring of fultoportulae (each with two satellite pores). Stephanodiscus neoaegypticus v. fekrii SEM. Fig. 14. Iconotype, external valve with a concave central area, marginal ring of fultoportula apertures and external opening of a rimoportula (arrowed). Scale bars = 10 µm (Figs 9–11, 14), 1 µm (Fig. 12), and 2 µm (Fig. 13).
FIGURE 1 in Stephanodiscus Ehr. species from Holocene sediments in the Faiyum Depression (Middle Egypt)
FIGURE 1. Lake Qarun situated in northern part of the Faiyum Depression, Egypt. Three terrestrial sediment core locations are shown with QARU9 and 10 on the southern shore of the lake and GARK1 in the Gharak region of south west Faiyum. Note diatomite exposures are indicated to the west and northeast of the modern lake.
Volitional Action Control and Depression in Chronic Pain: Does Action versus State Orientation Moderate the Relations of Pain-Related Cognitions to Depression?
<p>The rationale of this study was to better understand the interplay between content- and function-focused variables that are assumed to contribute to depression due to motivational and volitional deficits. Therefore, we stepwise examined the conditional indirect and direct relations of pain-related cognitions to depression. Subjective helplessness was included as presumably mediating the relations of catastrophizing and thought suppression to depression due to motivational deficits. In addition, moderating effects of dispositional action versus state orientation were analyzed, whereby state orientation indicates volitional deficits in coping with distress<strong>. </strong></p> <p>The data acquisition for this project was funded by the German Pension Insurance (Deutsche Rentenversicherung Bund) and the Federal Ministry of Education and Research (BMBF) within the research priority “Chronic diseases and patient orientation” - Grant number: 0421-FSCP-0529.</p>
No relationship between frontal alpha asymmetry and depressive disorders in a multiverse analysis of five studies
<p>For decades, the frontal alpha asymmetry (FAA) – a disproportion in EEG alpha oscillations power between right and left frontal channels – has been one of the most popular measures of depressive disorders (DD) in electrophysiology studies. Patients with DD often manifest a left-sided FAA: relatively higher alpha power in the left versus right frontal lobe. Recently, however, multiple studies failed to confirm this effect, questioning its reproducibility. Our purpose is to thoroughly test the validity of FAA in depression by conducting a multiverse analysis – running many related analyses and testing the sensitivity of the effect to changes in the analytical approach – on data from five independent studies. Only 13 of the 270 analyses revealed significant results. We conclude the paper by discussing theoretical assumptions underlying the FAA and suggest a list of guidelines for improving and expanding the EEG data analysis in future FAA studies.</p>
Parental effects on inbreeding depression in a beetle with obligate parental care
<p><span>Inbreeding depression occurs when individuals who are closely related mate and produce offspring with reduced fitness. Although inbreeding depression is a genetic phenomenon, the magnitude of inbreeding depression can be influenced by environmental conditions and parental effects. In this study, we tested whether size-based parental effects influence the magnitude of inbreeding depression in an insect with elaborate and obligate parental care (the burying beetle, <em>Nicrophorus</em> <em>orbicollis</em>). We first tested for size-dependent maternal effects on offspring size using a phenotypic manipulation experiment where we created large and small adults by manipulating the amount of time they fed as larvae. Consistent with studies of other <em>Nicrophorus</em> species, we found that larger mothers produced larger offspring. We next tested for size-dependent parental effects on the magnitude of inbreeding depression in two traits: mean larval mass and survival from larval dispersal to eclosion. As in our first experiment, we found that larger parents produced larger offspring. However, larval mass was also influenced by the interaction between parental body size and inbreeding status: when parents were small, inbred larvae were smaller than outbred larvae, but when parents were large this pattern was reversed. In contrast, survival from larval dispersal to adult emergence showed inbreeding depression that was unaffected by parental body size. Our results suggest that size-based parental effects can generate variation in the magnitude of inbreeding depression. However, further work is needed to dissect the mechanisms through which this might occur and to better understand why parental size influences inbreeding depression in some traits but not others.</span></p>
Female genital lichen sclerosus is connected with a higher depression rate, decreased sexual quality of life and diminished work productivity.
<p>Data from the survey including: Work Productivity and Activity Impairment: General Health (WPAI:GH), Patient Health Questionnaire-9 (PHQ-9), The Sexual Quality of Life-Female (SQOL-F) questionnaires collected between January and December 2021 from the study and the control group. Fifty-one adult female patients with genital LS, filled out an online questionnaire and were enrolled in the study group. The corresponding control group consisted of 45 healthy women with a similar demographic status.</p>
Posterior default mode network activity underlies distracted interoceptive attention and provides an objective basis for low mindfulness and depression
<p>Interoceptive attention to internal sensory signals is fundamental to mindfulness. However, it is difficult to measure objectively, and the vast majority of investigations of the neural correlates of mindfulness-based attention rely on subjective and retrospective measures of distraction. In this study, we measured consistency of response times on a breath-monitoring task (instruction to respond every 2 breath cycles) to objectively measure interoceptive attention in individuals across the lifespan (15–91 years of age, n=324). Consistently timed responses were indicative of on-task attention, whereas variable delayed responses indicated distraction or mind-wandering. Signifying the importance of interoceptive attention consistency, we observed that this measure was positively correlated across subjects with performance across several exteroceptive cognitive tasks. Electroencephalographic (EEG) source reconstruction demonstrated that distraction on the eyes-closed task was associated with elevated alpha band (8–12 Hz) brain activity, particularly in posterior default mode network (pDMN) brain regions. The neural data revealed four important findings: 1) pDMN brain activity was inversely linked with functional connectivity to the fronto-parietal network (FPN), suggesting that pDMN-FPN interactions play a key role in the regulation of pDMN activity during interoceptive attention. 2) pDMN activity on distracted trials was inversely correlated with trait-level mindfulness. 3) A key hub of the pDMN, the isthmus region of the posterior cingulate cortex (ICC), showed elevated activity on distracted trials in individuals with self-reported depressive symptoms. 4) In an independent second experiment, pDMN activity was adaptively modulated by task difficulty that invoked different levels of distraction. These results identify an EEG-based neurophysiological marker (elevated pDMN alpha activity) underlying interoceptive distraction, which is correlated with subjective markers of mindfulness and depression and that can be adaptively modulated. Our findings, thus, provide a direct link between a neurophysiological substrate of interoceptive attention, and subjective ratings of mindfulness and depressed mood.</p>
Clinical Features, Socio-Cultural Characteristics, Sleep Patterns, and Depression in Fibromyalgia Patients from India: A Cross-Sectional Study
<p><strong>Introduction</strong>: Fibromyalgia is a complex and chronic disease with significant regional variation and lack of studies from Indian population.</p> <p><strong>Objective</strong>: Aim to investigate the clinical features of fibromyalgia patients in India, including the prevalence and distribution of comorbidities, sleep patterns, and depression.</p> <p><strong>Method</strong>: Cross-sectional analysis of consecutive patients attending outpatient Rheumatology clinic from 2019-2020 satisfying ACR2016 criteria for fibromyalgia.</p> <p><strong>Results:</strong></p> <p>Of the 121 patients enrolled in the study, the majority (93.4%) were female, with a female-to-male ratio of 14:1. The mean age of the patients was 45 ±11 years. The socio-cultural profile of the patients revealed that the majority were married (88%) and homemakers (68.8%), lived in nuclear families (56%) and were middle to upper middle class (68.6%). Contrary to the existing literature, a higher prevalence of fibromyalgia has been observed in people with a higher educational status. Common clinical symptoms were extensive body aches (100%), fatigue (88%), difficulty concentrating (69.4%), irritability and gastrointestinal complaints (58.5%). We observed a high prevalence of primary headache (76%), mainly migraine (42%) and compulsive behaviour (OCB) (71%). Sleep disturbances and depression were found to be significant factors associated with fibromyalgia. The patients reported various sleep problems, such as snoring, waking up at night, daytime sleepiness, and taking daytime naps. Most of the patients had mild (50.8%) to moderate (29%) depression, while a smaller proportion experienced severe (6.6%) symptoms. Most of the patients had low vitamin D(91%).</p> <p><strong>Conclusion</strong>: The demographic profile of Indian patients was similar to that reported in the literature but had varied socio-cultural profiles needing further community-based studies. The high prevalence of psychological comorbidities and sleep disturbances highlights their importance in managing FM patients.</p>
A Study to Describe Routine Treatment Pathways in Participants With Major Depression and Active Suicidal Ideation With Intent in Italy
ClinicalTrials.gov study NCT04463108. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Transcranial Direct Current Stimulation (tDCS) for Depression in Pregnancy: A Pilot Study
ClinicalTrials.gov study NCT02116127. IPD Sharing: Not stated. Countries: 1. Publications: 106.
Better Sleep in Psychiatric Care - Depression, Anxiety and PTSD
ClinicalTrials.gov study NCT04136054. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Telehealth Depression Treatments for Older Adults
ClinicalTrials.gov study NCT02600754. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Online Training for Addressing Perinatal Depression
ClinicalTrials.gov study NCT04919967. IPD Sharing: YES. Countries: 1. Publications: 7.
rTMS for Military TBI-related Depression
ClinicalTrials.gov study NCT05426967. IPD Sharing: YES. Countries: 1. Publications: 1.
Brief Group Intervention Using EFT (Emotional Freedom Techniques) for Depression in College Students
ClinicalTrials.gov study NCT01117532. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Journey to Balance: Development and Validation of Individualized Life Balance Intervention for Depression
ClinicalTrials.gov study NCT06975098. IPD Sharing: NO. Countries: 1. Publications: 41.
Pharmacogenomics on Individualized Precise Treatment of Patients with Depression
ClinicalTrials.gov study NCT05669391. IPD Sharing: NO. Countries: 1. Publications: 11.
Confirmatory Efficacy Trial of Attention Bias Modification for Depression
ClinicalTrials.gov study NCT06361095. IPD Sharing: YES. Countries: 1. Publications: 1.
Comparing the Effects of Four Types of Electroconvulsive Therapy on Mood and Thinking in People With Depression
ClinicalTrials.gov study NCT00487500. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.